Hanes, Justin

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

Suk, J. S., Xu, Q., Kim, N., Hanes, J., & Ensign, L. M. (2016) · Advanced Drug Delivery Reviews

Nanoparticle-Based Drug DeliveryAdvanced Drug Delivery Systems

Cited by 4,523

Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus

Lai, S. K., O'Hanlon, D. E., Harrold, S., Man, S. T., Wang, Y.-Y., Cone, R., & Hanes, J. (2007) · Proceedings of the National Academy of Sciences

Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery

Cited by 1,050

A Dense Poly(Ethylene Glycol) Coating Improves Penetration of Large Polymeric Nanoparticles Within Brain Tissue

Nance, E. A., Woodworth, G. F., Sailor, K. A., Shih, T.-Y., Xu, Q., Swaminathan, G., Xiang, D., Eberhart, C., & Hanes, J. (2012) · Science Translational Medicine

Nanoparticle-Based Drug DeliveryBarrier Structure and Function Studies

Cited by 649

Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo

Xu, Q., Ensign, L. M., Boylan, N. J., Schön, A., Gong, X., Yang, J.-C., Lamb, N. W., Cai, S., Yu, T., Freire, E., et al. (2015) · ACS Nano

Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery

Cited by 568

Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier

Tang, B. C., Dawson, M., Lai, S. K., Wang, Y.-Y., Suk, J. S., Yang, M., Zeitlin, P., Boyle, M. P., Fu, J., & Hanes, J. (2009) · Proceedings of the National Academy of Sciences

Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery

Cited by 453

A Theoretical Model of Erosion and Macromolecular Drug Release from Biodegrading Microspheres

Batycky, R. P., Hanes, J., Langer, R., & Edwards, D. A. (1997) · Journal of Pharmaceutical Sciences

Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery

Cited by 374

Mucus-Penetrating Nanoparticles for Vaginal Drug Delivery Protect Against Herpes Simplex Virus

Ensign, L. M., Tang, B. C., Wang, Y.-Y., Tse, T. A., Hoen, T., Cone, R., & Hanes, J. (2012) · Science Translational Medicine

Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery

Cited by 368

Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer

Elgogary, A., Xu, Q., Poore, B., Alt, J., Zimmermann, S. C., Zhao, L., Fu, J., Chen, B., Xia, S., Liu, Y., et al. (2016) · Proceedings of the National Academy of Sciences

Cancer, Hypoxia, and MetabolismPancreatic and Hepatic Oncology Research

Cited by 234

Highly compacted biodegradable DNA nanoparticles capable of overcoming the mucus barrier for inhaled lung gene therapy

Mastorakos, P., da Silva, A. L., Chisholm, J., Song, E., Choi, W. K., Boyle, M. P., Morales, M. M., Hanes, J., & Suk, J. S. (2015) · Proceedings of the National Academy of Sciences

RNA Interference and Gene DeliveryInhalation and Respiratory Drug Delivery

Cited by 210

Nanoparticles Coated with High Molecular Weight PEG Penetrate Mucus and Provide Uniform Vaginal and Colorectal Distribution in Vivo

Maisel, K., Reddy, M., Xu, Q., Chattopadhyay, S., Cone, R., Ensign, L. M., & Hanes, J. (2016) · Nanomedicine

Advanced Drug Delivery SystemsNanoparticle-Based Drug Delivery

Cited by 147

Protein nanocages that penetrate airway mucus and tumor tissue

Huang, X., Chisholm, J., Zhuang, J., Xiao, Y., Duncan, G., Chen, X., Suk, J. S., & Hanes, J. (2017) · Proceedings of the National Academy of Sciences

Nanoparticle-Based Drug DeliveryInhalation and Respiratory Drug Delivery

Cited by 131

N-acetylcysteine Enhances Cystic Fibrosis Sputum Penetration and Airway Gene Transfer by Highly Compacted DNA Nanoparticles

Suk, J. S., Boylan, N. J., Trehan, K., Tang, B. C., Schneider, C. S., Lin, J.-M. G., Boyle, M. P., Zeitlin, P. L., Lai, S. K., Cooper, M. J., et al. (2011) · Molecular Therapy

RNA Interference and Gene DeliveryInhalation and Respiratory Drug Delivery

Cited by 94

Highly PEGylated DNA Nanoparticles Provide Uniform and Widespread Gene Transfer in the Brain

Mastorakos, P., Zhang, C., Berry, S., Oh, Y., Lee, S., Eberhart, C. G., Woodworth, G. F., Suk, J. S., & Hanes, J. (2015) · Advanced Healthcare Materials

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 80

DNA nanoparticle-mediated thymulin gene therapy prevents airway remodeling in experimental allergic asthma

da Silva, A. L., Martini, S. V., Abreu, S. C., Samary, C. D. S., Diaz, B. L., Fernezlian, S., de Sá, V. K., Capelozzi, V. L., Boylan, N. J., Goya, R. G., et al. (2014) · Journal of Controlled Release

RNA Interference and Gene DeliveryAsthma and respiratory diseases

Cited by 61