Boelen, Anita

Thyroid function in critically ill patients

Fliers, E., Bianco, A. C., Langouche, L., & Boelen, A. (2015) · The Lancet Diabetes & Endocrinology

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 441

Beyond Low Plasma T3: Local Thyroid Hormone Metabolism during Inflammation and Infection

Boelen, A., Kwakkel, J., & Fliers, E. (2011) · Endocrine Reviews

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 287

Hypothalamic thyroid hormone catabolism acts as a gatekeeper for the seasonal control of body weight and reproduction

Barrett, P., Ebling, F. J. P., Schuhler, S., Wilson, D., Ross, A. W., Warner, A., Jethwa, P., Boelen, A., Visser, T. J., Ozanne, D. M., et al. (2007) · Endocrinology

Circadian rhythm and melatoninThyroid Disorders and Treatments

Cited by 286

Transporters MCT8 and OATP1C1 maintain murine brain thyroid hormone homeostasis

Mayerl, S., Müller, J., Bauer, R., Richert, S., Kassmann, C. M., Darras, V. M., Buder, K., Boelen, A., Visser, T. J., & Heuer, H. (2014) · Journal of Clinical Investigation

Thyroid Disorders and TreatmentsDrug Transport and Resistance Mechanisms

Cited by 281

An update on non-thyroidal illness syndrome

Fliers, E., & Boelen, A. (2021) · Journal of Endocrinological Investigation

Thyroid Disorders and TreatmentsClinical Nutrition and Gastroenterology

Cited by 218

Association between serum interleukin-6 and serum 3,5,3'-triiodothyronine in nonthyroidal illness.

Boelen, A., Platvoet-Ter Schiphorst, M. C., & Wiersinga, W. M. (1993) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 196

Fasting-Induced Changes in the Hypothalamus–Pituitary–Thyroid Axis

Boelen, A., Wiersinga, W. M., & Fliers, E. (2008) · Thyroid

Thyroid Disorders and TreatmentsRegulation of Appetite and Obesity

Cited by 194

The classic pathways of thyroid hormone metabolism

van der Spek, A. H., Fliers, E., & Boelen, A. (2017) · Molecular and Cellular Endocrinology

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 194

The molecular basis of the non-thyroidal illness syndrome

de Vries, E. M., Fliers, E., & Boelen, A. (2015) · Journal of Endocrinology

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 192

Simultaneous changes in central and peripheral components of the hypothalamus-pituitary-thyroid axis in lipopolysaccharide-induced acute illness in mice

Boelen, A., Kwakkel, J., Thijssen-Timmer, D., Alkemade, A., Fliers, E., & Wiersinga, W. (2004) · Journal of Endocrinology

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 159

MECHANISMS IN ENDOCRINOLOGY: Beyond the fixed setpoint of the hypothalamus–pituitary–thyroid axis

Fliers, E., Kalsbeek, A., & Boelen, A. (2014) · European Journal of Endocrinology

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 124

Induction of Type 3 Deiodinase Activity in Inflammatory Cells of Mice with Chronic Local Inflammation

Boelen, A., Kwakkel, J., Alkemade, A., Renckens, R., Kaptein, E., Kuiper, G., Wiersinga, W. M., & Visser, T. J. (2005) · Endocrinology

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 117

Induced illness in interleukin-6 (IL-6) knock-out mice: a causal role of IL-6 in the development of the low 3,5,3'-triiodothyronine syndrome.

Boelen, A., Maas, M. A., Lowik, C. W., Platvoet, M. C., & Wiersinga, W. M. (1996) · Endocrinology

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 108

The role of cytokines in the lipopolysaccharide-induced sick euthyroid syndrome in mice

Boelen, A., Platvoet-ter Schiphorst, M. C., Bakker, O., & Wiersinga, W. M. (1995) · Journal of Endocrinology

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 93

Mutations in TBL1X Are Associated With Central Hypothyroidism

Heinen, C. A., Losekoot, M., Sun, Y., Watson, P. J., Fairall, L., Joustra, S. D., Zwaveling-Soonawala, N., Oostdijk, W., van den Akker, E. L. T., Alders, M., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsGenomics and Rare Diseases

Cited by 92

A Novel Role for the Thyroid Hormone-Activating Enzyme Type 2 Deiodinase in the Inflammatory Response of Macrophages

Kwakkel, J., Surovtseva, O. V., de Vries, E. M., Stap, J., Fliers, E., & Boelen, A. (2014) · Endocrinology

Thyroid Disorders and TreatmentsImmune Response and Inflammation

Cited by 88

Tissue-specific alterations in thyroid hormone homeostasis in combined Mct10 and Mct8 deficiency

Müller, J., Mayerl, S., Visser, T. J., Darras, V. M., Boelen, A., Frappart, L., Mariotta, L., Verrey, F., & Heuer, H. (2014) · Endocrinology

Thyroid Disorders and TreatmentsDrug Transport and Resistance Mechanisms

Cited by 88

Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging

Visser, W. E., Bombardieri, C. R., Zevenbergen, C., Barnhoorn, S., Ottaviani, A., van der Pluijm, I., Brandt, R., Kaptein, E., van Heerebeek, R., van Toor, H., et al. (2016) · PLOS ONE

Thyroid Disorders and TreatmentsGenetics, Aging, and Longevity in Model Organisms

Cited by 82

Impact of Early Nutrient Restriction During Critical Illness on the Nonthyroidal Illness Syndrome and Its Relation With Outcome: A Randomized, Controlled Clinical Study

Langouche, L., Vander Perre, S., Marques, M., Boelen, A., Wouters, P. J., Casaer, M. P., & Van den Berghe, G. (2013) · The Journal of Clinical Endocrinology & Metabolism

Clinical Nutrition and GastroenterologyEnhanced Recovery After Surgery

Cited by 79

A specific mutation in TBL1XR1 causes Pierpont syndrome

Heinen, C. A., Jongejan, A., Watson, P. J., Redeker, B., Boelen, A., Boudzovitch-Surovtseva, O., Forzano, F., Hordijk, R., Kelley, R., Olney, A. H., et al. (2016) · Journal of Medical Genetics

Genomics and Rare DiseasesGenetics and Neurodevelopmental Disorders

Cited by 73

Type 3 Deiodinase Is Highly Expressed in Infiltrating Neutrophilic Granulocytes in Response to Acute Bacterial Infection

Boelen, A., Boorsma, J., Kwakkel, J., Wieland, C. W., Renckens, R., Visser, T. J., Fliers, E., & Wiersinga, W. M. (2008) · Thyroid

Thyroid Disorders and TreatmentsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 70

Photoperiod and acute energy deficits interact on components of the thyroid hormone system in hypothalamic tanycytes of the Siberian hamster

Herwig, A., Wilson, D., Logie, T. J., Boelen, A., Morgan, P. J., Mercer, J. G., & Barrett, P. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Regulation of Appetite and ObesityThyroid Disorders and Treatments

Cited by 66

Adrenoleukodystrophy Newborn Screening in the Netherlands (SCAN Study): The X-Factor

Barendsen, R. W., Dijkstra, I. M. E., Visser, W. F., Alders, M., Bliek, J., Boelen, A., Bouva, M. J., van der Crabben, S. N., Elsinghorst, E., van Gorp, A. G. M., et al. (2020) · Frontiers in Cell and Developmental Biology

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 65

Chronic local inflammation in mice results in decreased TRH and type 3 deiodinase mRNA expression in the hypothalamic paraventricular nucleus independently of diminished food intake

Boelen, A., Kwakkel, J., Wiersinga, W. M., & Fliers, E. (2006) · Journal of Endocrinology

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 64