Ng, Lai Guan

Dimensionality reduction for visualizing single-cell data using UMAP

Becht, E., McInnes, L., Healy, J., Dutertre, C.-A., Kwok, I. W. H., Ng, L. G., Ginhoux, F., & Newell, E. W. (2019) · Nature Biotechnology

Single-cell and spatial transcriptomicsFace and Expression Recognition

Cited by 5,358

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., et al. (2010) · Science

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 5,175

The gut microbiota influences blood-brain barrier permeability in mice

Braniste, V., Al-Asmakh, M., Kowal, C., Anuar, F., Abbaspour, A., Tóth, M., Korecka, A., Bakocevic, N., Ng, L. G., Kundu, P., et al. (2014) · Science Translational Medicine

Barrier Structure and Function StudiesGut microbiota and health

Cited by 2,530

C-Myb+ Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages

Hoeffel, G., Chen, J., Lavin, Y., Low, D., Almeida, F. F., See, P., Beaudin, A. E., Lum, J., Low, I., Forsberg, E. C., et al. (2015) · Immunity

Hematopoietic Stem Cell TransplantationImmune cells in cancer

Cited by 1,135

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

Chakarov, S., Lim, H. Y., Tan, L., Lim, S. Y., See, P., Lum, J., Zhang, X.-M., Foo, S., Nakamizo, S., Duan, K., et al. (2019) · Science

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 1,114

Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19

Silvin, A., Chapuis, N., Dunsmore, G., Goubet, A.-G., Dubuisson, A., Derosa, L., Almire, C., Hénon, C., Kosmider, O., Droin, N., et al. (2020) · Cell

COVID-19 Clinical Research StudiesInflammation biomarkers and pathways

Cited by 834

Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages

Hoeffel, G., Wang, Y., Greter, M., See, P., Teo, P., Malleret, B., Leboeuf, M., Low, D., Oller, G., Almeida, F., et al. (2012) · Journal of Experimental Medicine

Immunotherapy and Immune ResponsesHematopoietic Stem Cell Transplantation

Cited by 786

A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart

Nicolás-Ávila, J. A., Lechuga-Vieco, A. V., Esteban-Martínez, L., Sánchez-Díaz, M., Díaz-García, E., Santiago, D. J., Rubio-Ponce, A., Li, J. L., Balachander, A., Quintana, J. A., et al. (2020) · Cell

Autophagy in Disease and TherapyPhagocytosis and Immune Regulation

Cited by 762

Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells

Liu, Z., Gu, Y., Chakarov, S., Bleriot, C., Kwok, I., Chen, X., Shin, A., Huang, W., Dress, R. J., Dutertre, C.-A., et al. (2019) · Cell

Immune cells in cancerAtherosclerosis and Cardiovascular Diseases

Cited by 719

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Cossarizza, A., Chang, H., Radbruch, A., Abrignani, S., Addo, R., Akdis, M., Andrä, I., Andreata, F., Annunziato, F., Arranz, E., et al. (2021) · European Journal of Immunology

T-cell and B-cell ImmunologyMonoclonal and Polyclonal Antibodies Research

Cited by 531

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen

Lim, H. Y., Lim, S. Y., Tan, C. K., Thiam, C. H., Goh, C. C., Carbajo, D., Chew, S. H. S., See, P., Chakarov, S., Wang, X. N., et al. (2018) · Immunity

Proteoglycans and glycosaminoglycans researchAtherosclerosis and Cardiovascular Diseases

Cited by 384

DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling

Tal, O., Lim, H. Y., Gurevich, I., Milo, I., Shipony, Z., Ng, L. G., Angeli, V., & Shakhar, G. (2011) · Journal of Experimental Medicine

Lymphatic System and DiseasesChemokine receptors and signaling

Cited by 269

A subset of Kupffer cells regulates metabolism through the expression of CD36

Blériot, C., Barreby, E., Dunsmore, G., Ballaire, R., Chakarov, S., Ficht, X., De Simone, G., Andreata, F., Fumagalli, V., Guo, W., et al. (2021) · Immunity

Immune cells in cancerLiver physiology and pathology

Cited by 236

Deciphering spatial domains from spatial multi-omics with SpatialGlue

Long, Y., Ang, K. S., Sethi, R., Liao, S., Heng, Y., van Olst, L., Ye, S., Zhong, C., Xu, H., Zhang, D., et al. (2024) · Nature Methods

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 223

NIR‐II‐Excited Intravital Two‐Photon Microscopy Distinguishes Deep Cerebral and Tumor Vasculatures with an Ultrabright NIR‐I AIE Luminogen

Wang, S., Liu, J., Goh, C. C., Ng, L. G., & Liu, B. (2019) · Advanced Materials

Luminescence and Fluorescent MaterialsOptical Imaging and Spectroscopy Techniques

Cited by 148

CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses

Chong, S. Z., Evrard, M., Devi, S., Chen, J., Lim, J. Y., See, P., Zhang, Y., Adrover, J. M., Lee, B., Tan, L., et al. (2016) · Journal of Experimental Medicine

Chemokine receptors and signalingImmune cells in cancer

Cited by 142

NIR‐II Excitable Conjugated Polymer Dots with Bright NIR‐I Emission for Deep In Vivo Two‐Photon Brain Imaging Through Intact Skull

Wang, S., Liu, J., Feng, G., Ng, L. G., & Liu, B. (2019) · Advanced Functional Materials

Luminescence and Fluorescent MaterialsAdvanced Fluorescence Microscopy Techniques

Cited by 110

Resident macrophages restrain pathological adipose tissue remodeling and protect vascular integrity in obese mice

Chen, Q., Lai, S. M., Xu, S., Tan, Y., Leong, K., Liu, D., Tan, J. C., Naik, R. R., Barron, A. M., Adav, S. S., et al. (2021) · The EMBO Reports

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 56

Conditional knockout of hypoxia-inducible factor 1-alpha in tumor-infiltrating neutrophils protects against pancreatic ductal adenocarcinoma

Sieow, J. L., Penny, H. L., Gun, S. Y., Tan, L. Q., Duan, K., Yeong, J. P. S., Pang, A., Lim, D., Toh, H. C., Lim, T. K. H., et al. (2023) · International Journal of Molecular Sciences

Immune cells in cancerCancer, Hypoxia, and Metabolism

Cited by 27