Gelernter, Joel

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Demontis, D., Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, 23andMe Research Team, Walters, R. K., Martin, J., Mattheisen, M., Als, T. D., Agerbo, E., Baldursson, G., et al. (2019) · Nature Genetics

Attention Deficit Hyperactivity DisorderGenetic Associations and Epidemiology

Cited by 2,203

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Mullins, N., Forstner, A. J., O’Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z., Als, T. D., Bigdeli, T. B., Børte, S., Bryois, J., et al. (2021) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,517

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Lee, P. H., Anttila, V., Won, H., Feng, Y.-C. A., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., et al. (2019) · Cell

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 1,381

Brain-Derived Neurotrophic Factor–5-HTTLPR Gene Interactions and Environmental Modifiers of Depression in Children

Kaufman, J., Yang, B.-Z., Douglas-Palumberi, H., Grasso, D., Lipschitz, D., Houshyar, S., Krystal, J. H., & Gelernter, J. (2006) · Biological Psychiatry

Neurotransmitter Receptor Influence on BehaviorChild Abuse and Trauma

Cited by 692

Psychiatric Genomics: An Update and an Agenda

Sullivan, P. F., Agrawal, A., Bulik, C. M., Andreassen, O. A., Børglum, A. D., Breen, G., Cichon, S., Edenberg, H. J., Faraone, S. V., Gelernter, J., et al. (2018) · American Journal of Psychiatry

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 676

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C.-Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., et al. (2019) · Nature Communications

Posttraumatic Stress Disorder ResearchGenetic Associations and Epidemiology

Cited by 635

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23andMe Research Team, Walters, R. K., Polimanti, R., Johnson, E. C., McClintick, J. N., Adams, M. J., Adkins, A. E., Aliev, F., Bacanu, S.-A., Batzler, A., et al. (2018) · Nature Neuroscience

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 632

A Functional Polymorphism of the μ-Opioid Receptor Gene is Associated with Naltrexone Response in Alcohol-Dependent Patients

Oslin, D. W., Berrettini, W., Kranzler, H. R., Pettinati, H., Gelernter, J., Volpicelli, J. R., & O'Brien, C. P. (2003) · Neuropsychopharmacology

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 571

Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program

Verma, A., Huffman, J. E., Rodriguez, A., Conery, M., Liu, M., Ho, Y.-L., Kim, Y., Heise, D. A., Guare, L., Panickan, V. A., et al. (2024) · Science

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 463

Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability

Duncan, L. E., Ratanatharathorn, A., Aiello, A. E., Almli, L. M., Amstadter, A. B., Ashley-Koch, A. E., Baker, D. G., Beckham, J. C., Bierut, L. J., Bisson, J., et al. (2018) · Molecular Psychiatry

Posttraumatic Stress Disorder ResearchGenetic Associations and Epidemiology

Cited by 425

Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions

Levey, D. F., Stein, M. B., Wendt, F. R., Pathak, G. A., Zhou, H., Aslan, M., Quaden, R., Harrington, K. M., Nuñez, Y. Z., Overstreet, C., et al. (2021) · Nature Neuroscience

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 422

A prospective cohort study investigating factors associated with depression during medical internship

Sen, S., Kranzler, H. R., Krystal, J. H., Speller, H., Chan, G., Gelernter, J., & Guille, C. (2010) · Archives of General Psychiatry

Healthcare professionals’ stress and burnoutInnovations in Medical Education

Cited by 411

Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD

Saccone, N. L., Culverhouse, R. C., Schwantes-An, T.-H., Cannon, D. S., Chen, X., Cichon, S., Giegling, I., Han, S., Han, Y., Keskitalo-Vuokko, K., et al. (2010) · PLoS Genetics

Smoking Behavior and CessationGenetic Associations and Epidemiology

Cited by 395

Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder

Xie, P., Kranzler, H. R., Poling, J., Stein, M. B., Anton, R. F., Farrer, L. A., & Gelernter, J. (2010) · Neuropsychopharmacology

Posttraumatic Stress Disorder ResearchChild Abuse and Trauma

Cited by 327

Child abuse, depression, and methylation in genes involved with stress, neural plasticity, and brain circuitry

Weder, N., Zhang, H., Jensen, K., Yang, B. Z., Simen, A., Jackowski, A., Lipschitz, D., Douglas-Palumberi, H., Ge, M., Perepletchikova, F., et al. (2014) · Journal of the American Academy of Child & Adolescent Psychiatry

Child Abuse and TraumaEpigenetics and DNA Methylation

Cited by 324

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.

Karlsson Linnér, R., Mallard, T. T., Barr, P. B., Sanchez-Roige, S., Madole, J. W., Driver, M. N., Poore, H. E., de Vlaming, R., Grotzinger, A. D., Tielbeek, J. J., et al. (2021) · Nature Neuroscience

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 317

Allelic and haplotypic association of GABRA2 with alcohol dependence

Covault, J., Gelernter, J., Hesselbrock, V., Nellissery, M., & Kranzler, H. R. (2004) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 273

Adverse childhood events as risk factors for substance dependence: partial mediation by mood and anxiety disorders

Douglas, K. R., Chan, G., Gelernter, J., Arias, A. J., Anton, R. F., Weiss, R. D., Brady, K., Poling, J., Farrer, L., & Kranzler, H. R. (2010) · Addictive Behaviors

Child Abuse and TraumaSubstance Abuse Treatment and Outcomes

Cited by 269

Interactive Effect of Stressful Life Events and the Serotonin Transporter 5-HTTLPR Genotype on Posttraumatic Stress Disorder Diagnosis in 2 Independent Populations

Xie, P., Kranzler, H. R., Poling, J., Stein, M. B., Anton, R. F., Brady, K., Weiss, R. D., Farrer, L., & Gelernter, J. (2009) · Archives of General Psychiatry

Posttraumatic Stress Disorder ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 264

Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity

Tyrka, A. R., Price, L. H., Gelernter, J., Schepker, C., Anderson, G. M., & Carpenter, L. L. (2009) · Biological Psychiatry

Stress Responses and CortisolChild Abuse and Trauma

Cited by 264

Child abuse and epigenetic mechanisms of disease risk

Yang, B.-Z., Zhang, H., Ge, W., Weder, N., Douglas-Palumberi, H., Perepletchikova, F., Gelernter, J., & Kaufman, J. (2013) · American Journal of Preventive Medicine

Child Abuse and TraumaEpigenetics and DNA Methylation

Cited by 256

Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders

Stein, M. B., Schork, N. J., & Gelernter, J. (2008) · Neuropsychopharmacology

Neurotransmitter Receptor Influence on BehaviorAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 247

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Hatoum, A. S., Colbert, S. M. C., Johnson, E. C., Huggett, S. B., Deak, J. D., Pathak, G. A., Jennings, M. V., Paul, S. E., Karcher, N. R., Hansen, I., et al. (2023) · Nature Mental Health

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 241

Genetic and Environmental Predictors of Early Alcohol Use

Kaufman, J., Yang, B.-Z., Douglas-Palumberi, H., Crouse-Artus, M., Lipschitz, D., Krystal, J. H., & Gelernter, J. (2007) · Biological Psychiatry

Child Abuse and TraumaSubstance Abuse Treatment and Outcomes

Cited by 216