Edenberg, Howard J.

Association of GABRA2 with drug dependence in the collaborative study of the genetics of alcoholism sample

Agrawal, A., Edenberg, H. J., Foroud, T., Bierut, L. J., Dunne, G., Hinrichs, A. L., Nurnberger, J. I., Crowe, R., Kuperman, S., Schuckit, M. A., et al. (2006) · Behavior Genetics

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 189

GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors

Docherty, A. R., Mullins, N., Ashley-Koch, A. E., Qin, X., Coleman, J. R. I., Shabalin, A., Kang, J., Murnyak, B., Wendt, F., Adams, M., et al. (2023) · American Journal of Psychiatry

Genetic Associations and EpidemiologySuicide and Self-Harm Studies

Cited by 160

A Risk Allele for Nicotine Dependence in CHRNA5 Is a Protective Allele for Cocaine Dependence

Grucza, R. A., Wang, J. C., Stitzel, J. A., Hinrichs, A. L., Saccone, S. F., Saccone, N. L., Bucholz, K. K., Cloninger, C. R., Neuman, R. J., Budde, J. P., et al. (2008) · Biological Psychiatry

Smoking Behavior and CessationGenetic Associations and Epidemiology

Cited by 152

Singleton deletions throughout the genome increase risk of bipolar disorder

Zhang, D., Cheng, L., Qian, Y., Alliey-Rodriguez, N., Kelsoe, J. R., Greenwood, T., Nievergelt, C., Barrett, T. B., McKinney, R., Schork, N., et al. (2009) · Molecular Psychiatry

Bipolar Disorder and TreatmentGenomic variations and chromosomal abnormalities

Cited by 148

Towards understanding the schizophrenia code: an expanded convergent functional genomics approach

Le‐Niculescu, H., Balaraman, Y., Patel, S., Tan, J., Sidhu, K., Jerome, R. E., Edenberg, H. J., Kuczenski, R., Geyer, M. A., Nurnberger, J. I., et al. (2007) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 137

Predicting Sensation Seeking From Dopamine Genes: A Candidate-System Approach

Derringer, J., Krueger, R. F., Dick, D. M., Saccone, S., Grucza, R. A., Agrawal, A., Lin, P., Almasy, L., Edenberg, H. J., Foroud, T., et al. (2010) · Psychological Science

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 114

Genome-wide association study of conduct disorder symptomatology

Dick, D. M., Aliev, F., Krueger, R. F., Edwards, A., Agrawal, A., Lynskey, M., Lin, P., Schuckit, M., Hesselbrock, V, Nurnberger, J., et al. (2011) · Molecular Psychiatry

Psychopathy, Forensic Psychiatry, Sexual OffendingGenetic Associations and Epidemiology

Cited by 111

Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium

Polimanti, R., Peterson, R. E., Ong, J.-S., MacGregor, S., Edwards, A. C., Clarke, T.-K., Frank, J., Gerring, Z., Gillespie, N. A., Lind, P. A., et al. (2019) · Psychological Medicine

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 108

Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium

Polimanti, R., Peterson, R. E., Ong, J.-S., MacGregor, S., Edwards, A. C., Clarke, T.-K., Frank, J., Gerring, Z., Gillespie, N. A., Lind, P. A., et al. (2018) · Psychological Medicine

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 108

Stress–response pathways are altered in the hippocampus of chronic alcoholics

McClintick, J. N., Xuei, X., Tischfield, J. A., Goate, A., Foroud, T., Wetherill, L., Ehringer, M. A., & Edenberg, H. J. (2013) · Alcohol

Stress Responses and CortisolSubstance Abuse Treatment and Outcomes

Cited by 105

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

Kapoor, M., Wang, J.-C., Farris, S. P., Liu, Y., McClintick, J., Gupta, I., Meyers, J. L., Bertelsen, S., Chao, M., Nurnberger, J., et al. (2019) · Translational Psychiatry

Substance Abuse Treatment and OutcomesAlcohol Consumption and Health Effects

Cited by 92

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

Andersen, A. M., Pietrzak, R. H., Kranzler, H. R., Ma, L., Zhou, H., Liu, X., Kramer, J., Kuperman, S., Edenberg, H. J., Nurnberger, J. I., et al. (2017) · JAMA Psychiatry

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 90

Association of NFKB1, which encodes a subunit of the transcription factor NF- B, with alcohol dependence

Edenberg, H. J., Xuei, X., Wetherill, L. F., Bierut, L., Bucholz, K., Dick, D. M., Hesselbrock, V., Kuperman, S., Porjesz, B., Schuckit, M. A., et al. (2007) · Human Molecular Genetics

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 89

Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence

Wetherill, L., Schuckit, M. A., Hesselbrock, V., Xuei, X., Liang, T., Dick, D. M., Kramer, J., Nurnberger Jr., J. I., Tischfield, J. A., Porjesz, B., et al. (2008) · Alcoholism: Clinical and Experimental Research

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 83

Predicting risk for Alcohol Use Disorder using longitudinal data with multimodal biomarkers and family history: a machine learning study

Kinreich, S., Meyers, J. L., Maron-Katz, A., Kamarajan, C., Pandey, A. K., Chorlian, D. B., Zhang, J., Pandey, G., Subbie-Saenz de Viteri, S., Pitti, D., et al. (2021) · Molecular Psychiatry

Substance Abuse Treatment and OutcomesGenetic Associations and Epidemiology

Cited by 80

Examining Sex-Differentiated Genetic Effects Across Neuropsychiatric and Behavioral Traits

Martin, J., Khramtsova, E. A., Goleva, S. B., Blokland, G. A. M., Traglia, M., Walters, R. K., Hübel, C., Coleman, J. R. I., Breen, G., Børglum, A. D., et al. (2021) · Biological Psychiatry

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 79

Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers

Hartz, S. M., Short, S. E., Saccone, N. L., Culverhouse, R., Chen, L., Schwantes-An, T.-H., Coon, H., Han, Y., Stephens, S. H., Sun, J., et al. (2012) · Archives of General Psychiatry

Smoking Behavior and CessationGenetic Associations and Epidemiology

Cited by 75

Ethanol-associated changes in glutamate reward neurocircuitry: a minireview of clinical and preclinical genetic findings

Bell, R. L., Hauser, S. R., McClintick, J., Rahman, S., Edenberg, H. J., Szumlinski, K. K., & McBride, W. J. (2016) · Progress in molecular biology and translational science

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 65

Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples

Barr, P. B., Ksinan, A., Su, J., Johnson, E. C., Meyers, J. L., Wetherill, L., Latvala, A., Aliev, F., Chan, G., Kuperman, S., et al. (2020) · Translational Psychiatry

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 59

GABRR1 and GABRR2, encoding the GABA‐A receptor subunits ρ1 and ρ2, are associated with alcohol dependence

Xuei, X., Flury‐Wetherill, L., Dick, D., Goate, A., Tischfield, J., Nurnberger, J., Schuckit, M., Kramer, J., Kuperman, S., Hesselbrock, V., et al. (2010) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 47

Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior

Salvatore, J. E., Edwards, A. C., McClintick, J. N., Bigdeli, T. B., Adkins, A., Aliev, F., Edenberg, H. J., Foroud, T., Hesselbrock, V, Kramer, J., et al. (2015) · Translational Psychiatry

Genetic Associations and EpidemiologyPsychopathy, Forensic Psychiatry, Sexual Offending

Cited by 42

Clinical implications of tolerance to alcohol in nondependent young drinkers

Schuckit, M. A., Smith, T. L., Hesselbrock, V., Bucholz, K. K., Bierut, L., Edenberg, H., Kramer, J., Longacre, E., Fukukura, T., Kalmijn, J., et al. (2008) · The American Journal of Drug and Alcohol Abuse

Substance Abuse Treatment and OutcomesAlcohol Consumption and Health Effects

Cited by 36

Meta-Analyses of Genome-Wide Association Data Hold New Promise for Addiction Genetics

Agrawal, A., Edenberg, H. J., & Gelernter, J. (2016) · Journal of Studies on Alcohol and Drugs

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 32

Ethanol treatment of lymphoblastoid cell lines from alcoholics and non-alcoholics causes many subtle changes in gene expression

McClintick, J. N., Brooks, A. I., Deng, L., Liang, L., Wang, J. C., Kapoor, M., Xuei, X., Foroud, T., Tischfield, J. A., & Edenberg, H. J. (2014) · Alcohol

Alcohol Consumption and Health EffectsSubstance Abuse Treatment and Outcomes

Cited by 25