Davidson, Beverly L.

Transvascular delivery of small interfering RNA to the central nervous system

Kumar, P., Wu, H., McBride, J. L., Jung, K.-E., Hee Kim, M., Davidson, B. L., Kyung Lee, S., Shankar, P., & Manjunath, N. (2007) · Nature

RNA Interference and Gene DeliveryBarrier Structure and Function Studies

Cited by 1,246

Lysosomal storage diseases

Platt, F. M., d’Azzo, A., Davidson, B. L., Neufeld, E. F., & Tifft, C. J. (2018) · Nature Reviews Disease Primers

Lysosomal Storage Disorders ResearchGlycogen Storage Diseases and Myoclonus

Cited by 1,052

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

Harper, S. Q., Staber, P. D., He, X., Eliason, S. L., Martins, I. H., Mao, Q., Yang, L., Kotin, R. M., Paulson, H. L., & Davidson, B. L. (2005) · Proceedings of the National Academy of Sciences

Genetic Neurodegenerative DiseasesRNA Interference and Gene Delivery

Cited by 682

The Bifunctional microRNA miR-9/miR-9* Regulates REST and CoREST and Is Downregulated in Huntington's Disease

Packer, A. N., Xing, Y., Harper, S. Q., Jones, L., & Davidson, B. L. (2008) · The Journal of Neuroscience

Genetic Neurodegenerative DiseasesMicroRNA in disease regulation

Cited by 679

Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system

Davidson, B. L., Stein, C. S., Heth, J. A., Martins, I., Kotin, R. M., Derksen, T. A., Zabner, J., Ghodsi, A., & Chiorini, J. A. (2000) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 531

Identification of PDGFR as a receptor for AAV-5 transduction

Pasquale, G. D., Davidson, B. L., Stein, C. S., Martins, I., Scudiero, D., Monks, A., & Chiorini, J. A. (2003) · Nature Medicine

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 355

Gene therapy for lysosomal storage diseases

Sands, M. S., & Davidson, B. L. (2006) · Molecular Therapy

Lysosomal Storage Disorders ResearchVirus-based gene therapy research

Cited by 285

Disease-Associated Short Tandem Repeats Co-localize with Chromatin Domain Boundaries

Sun, J. H., Zhou, L., Emerson, D. J., Phyo, S. A., Titus, K. R., Gong, W., Gilgenast, T. G., Beagan, J. A., Davidson, B. L., Tassone, F., et al. (2018) · Cell

Genetic Neurodegenerative DiseasesGenomics and Chromatin Dynamics

Cited by 249

Preclinical Safety of RNAi-Mediated HTT Suppression in the Rhesus Macaque as a Potential Therapy for Huntington's Disease

McBride, J. L., Pitzer, M. R., Boudreau, R. L., Dufour, B., Hobbs, T., Ojeda, S. R., & Davidson, B. L. (2011) · Molecular Therapy

Genetic Neurodegenerative DiseasesRNA Interference and Gene Delivery

Cited by 247

Striatal neurons directly converted from Huntington’s disease patient fibroblasts recapitulate age-associated disease phenotypes

Victor, M. B., Richner, M., Olsen, H. E., Lee, S. W., Monteys, A. M., Ma, C., Huh, C. J., Zhang, B., Davidson, B. L., Yang, X. W., et al. (2018) · Nature Neuroscience

Genetic Neurodegenerative DiseasesPluripotent Stem Cells Research

Cited by 246

Transcriptome-wide Discovery of microRNA Binding Sites in Human Brain

Boudreau, R. L., Jiang, P., Gilmore, B. L., Spengler, R. M., Tirabassi, R., Nelson, J. A., Ross, C. A., Xing, Y., & Davidson, B. L. (2014) · Neuron

MicroRNA in disease regulationRNA Research and Splicing

Cited by 217

Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain

Hudry, E., Dashkoff, J., Roe, A. D., Takeda, S., Koffie, R. M., Hashimoto, T., Scheel, M., Spires-Jones, T., Arbel-Ornath, M., Betensky, R., et al. (2013) · Science Translational Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 187

Viral Vectors for Gene Transfer

Chen, Y. H., Keiser, M. S., & Davidson, B. L. (2018) · Current Protocols in Mouse Biology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 146

AAV gene transfer delays disease onset in a TPP1-deficient canine model of the late infantile form of Batten disease

Katz, M. L., Tecedor, L., Chen, Y., Williamson, B. G., Lysenko, E., Wininger, F. A., Young, W. M., Johnson, G. C., Whiting, R. E. H., Coates, J. R., et al. (2015) · Science Translational Medicine

Lysosomal Storage Disorders ResearchVirus-based gene therapy research

Cited by 134

The Transcription Factor ATF4 Promotes Skeletal Myofiber Atrophy during Fasting

Ebert, S. M., Monteys, A. M., Fox, D. K., Bongers, K. S., Shields, B. E., Malmberg, S. E., Davidson, B. L., Suneja, M., & Adams, C. M. (2010) · Molecular Endocrinology

Muscle Physiology and DisordersEndoplasmic Reticulum Stress and Disease

Cited by 130

Adeno-Associated Virus Type 5: Transduction Efficiency and Cell-Type Specificity in the Primate Retina

Lotery, A. J., Yang, G. S., Mullins, R. F., Russell, S. R., Schmidt, M., Stone, E. M., Lindbloom, J. D., Chiorini, J. A., Kotin, R. M., & Davidson, B. L. (2003) · Human Gene Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 107

PIAS1 regulates mutant Huntingtin accumulation and Huntington’s disease-associated phenotypes in vivo

Ochaba, J., Monteys, A. M., O’Rourke, J. G., Reidling, J. C., Steffan, J. S., Davidson, B. L., & Thompson, L. M. (2016) · Neuron

Genetic Neurodegenerative DiseasesLysosomal Storage Disorders Research

Cited by 94

Transduction of Nonhuman Primate Brain with Adeno-Associated Virus Serotype 1: Vector Trafficking and Immune Response

Hadaczek, P., Forsayeth, J., Mirek, H., Munson, K., Bringas, J., Pivirotto, P., L McBride, J., Davidson, B. L., & Bankiewicz, K. S. (2009) · Human Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 90

APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease

Jackson, R. J., Keiser, M. S., Meltzer, J. C., Fykstra, D. P., Dierksmeier, S. E., Hajizadeh, S., Kreuzer, J., Morris, R., Melloni, A., Nakajima, T., et al. (2024) · Molecular Therapy

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 86

Adeno-associated virus type 4 (AAV4) targets ependyma and astrocytes in the subventricular zone and RMS

Liu, G., Martins, I. H., Chiorini, J. A., & Davidson, B. L. (2005) · Gene Therapy

Virus-based gene therapy researchNeurogenesis and neuroplasticity mechanisms

Cited by 84

Toxicity after AAV delivery of RNAi expression constructs into nonhuman primate brain

Keiser, M. S., Ranum, P. T., Yrigollen, C. M., Carrell, E. M., Smith, G. R., Muehlmatt, A. L., Chen, Y. H., Stein, J. M., Wolf, R. L., Radaelli, E., et al. (2021) · Nature Medicine

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 79

Mapping PTBP2 binding in human brain identifies SYNGAP1 as a target for therapeutic splice switching

Dawicki-McKenna, J. M., Felix, A. J., Waxman, E. A., Cheng, C., Amado, D. A., Ranum, P. T., Bogush, A., Dungan, L. V., Maguire, J. A., Gagne, A. L., et al. (2023) · Nature Communications

RNA Research and SplicingGenetics and Neurodevelopmental Disorders

Cited by 41

The Transcription Factor ATF4 Promotes Skeletal Myofiber Atrophy during Fasting

Ebert, S. M., Monteys, A. M., Fox, D. K., Bongers, K. S., Shields, B. E., Malmberg, S. E., Davidson, B. L., Suneja, M., & Adams, C. M. (2010) · The Journal of Clinical Endocrinology & Metabolism

Muscle Physiology and DisordersEndoplasmic Reticulum Stress and Disease

Cited by 3