Pfeffer, Klaus

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

Arpaia, N., Campbell, C., Fan, X., Dikiy, S., van der Veeken, J., deRoos, P., Liu, H., Cross, J. R., Pfeffer, K., Coffer, P. J., et al. (2013) · Nature

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 4,838

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

Pfeffer, K., Matsuyama, T., Kündig, T. M., Wakeham, A., Kishihara, K., Shahinian, A., Wiegmann, K., Ohashi, P. S., Krönke, M., & Mak, T. W. (1993) · Cell

Immune Response and InflammationNF-κB Signaling Pathways

Cited by 1,677

Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment

Schulte-Schrepping, J., Reusch, N., Paclik, D., Baßler, K., Schlickeiser, S., Zhang, B., Krämer, B., Krammer, T., Brumhard, S., Bonaguro, L., et al. (2020) · Cell

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 1,461

Pretreatment of Mice with Streptomycin Provides a Salmonella enterica Serovar Typhimurium Colitis Model That Allows Analysis of Both Pathogen and Host

Barthel, M., Hapfelmeier, S., Quintanilla-Martínez, L., Kremer, M., Rohde, M., Hogardt, M., Pfeffer, K., Rüssmann, H., & Hardt, W.-D. (2003) · Infection and Immunity

Salmonella and Campylobacter epidemiologyEscherichia coli research studies

Cited by 1,020

Swarm Learning for decentralized and confidential clinical machine learning

Warnat-Herresthal, S., Schultze, H., Shastry, K. L., Manamohan, S., Mukherjee, S., Garg, V., Sarveswara, R., Händler, K., Pickkers, P., Aziz, N. A., et al. (2021) · Nature

Privacy-Preserving Technologies in DataBlockchain Technology Applications and Security

Cited by 884

Genome-wide, large-scale production of mutant mice by ENU mutagenesis

de Angelis, M. H., Flaswinkel, H., Fuchs, H., Rathkolb, B., Soewarto, D., Marschall, S., Heffner, S., Pargent, W., Wuensch, K., Jung, M., et al. (2000) · Nature Genetics

Plant Genetic and Mutation StudiesCarcinogens and Genotoxicity Assessment

Cited by 664

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

Matsuyama, T., Kimura, T., Kitagawa, M., Pfeffer, K., Kawakami, T., Watanabe, N., Kündig, T. M., Amakawa, R., Kishihara, K., Wakeham, A., et al. (1993) · Cell

interferon and immune responsesImmune Response and Inflammation

Cited by 649

Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPS

Pilla, D. M., Hagar, J. A., Haldar, A. K., Mason, A. K., Degrandi, D., Pfeffer, K., Ernst, R. K., Yamamoto, M., Miao, E. A., & Coers, J. (2014) · Proceedings of the National Academy of Sciences

Inflammasome and immune disordersinterferon and immune responses

Cited by 357

Phosphorylation of the Stat1 Transactivation Domain Is Required for Full-Fledged IFN-γ-Dependent Innate Immunity

Varinou, L., Ramsauer, K., Karaghiosoff, M., Kolbe, T., Pfeffer, K., Müller, M., & Decker, T. (2003) · Immunity

Cytokine Signaling Pathways and Interactionsinterferon and immune responses

Cited by 284

Autoimmunity and Inflammation Due to a Gain-of-Function Mutation in Phospholipase Cγ2 that Specifically Increases External Ca2+ Entry

Yu, P., Constien, R., Dear, N., Katan, M., Hanke, P., Bunney, T. D., Kunder, S., Quintanilla-Martinez, L., Huffstadt, U., Schröder, A., et al. (2005) · Immunity

T-cell and B-cell ImmunologyImmunodeficiency and Autoimmune Disorders

Cited by 177

The proinflammatory cytokine-induced IRG1 protein associates with mitochondria

Degrandi, D., Hoffmann, R., Beuter-Gunia, C., & Pfeffer, K. (2009) · Journal of Interferon & Cytokine Research

Immune Response and InflammationImmune cells in cancer

Cited by 155

IL‐6 Trans‐signaling Controls Liver Regeneration After Partial Hepatectomy

Fazel Modares, N., Polz, R., Haghighi, F., Lamertz, L., Behnke, K., Zhuang, Y., Kordes, C., Häussinger, D., Sorg, U. R., Pfeffer, K., et al. (2019) · Hepatology

Liver physiology and pathologyCytokine Signaling Pathways and Interactions

Cited by 113

B and T Lymphocyte Attenuator Tempers Early Infection Immunity

Sun, Y., Brown, N. K., Ruddy, M. J., Miller, M. L., Lee, Y., Wang, Y., Murphy, K. M., Pfeffer, K., Chen, L., Kaye, J., et al. (2009) · The Journal of Immunology

T-cell and B-cell ImmunologyImmune Response and Inflammation

Cited by 51

Cutting Edge: The BTLA–HVEM Regulatory Pathway Interferes with Protective Immunity to Intestinal Helminth Infection

Breloer, M., Hartmann, W., Blankenhaus, B., Eschbach, M.-L., Pfeffer, K., & Jacobs, T. (2015) · The Journal of Immunology

Parasites and Host InteractionsT-cell and B-cell Immunology

Cited by 35

B Cell-Mediated Maintenance of Cluster of Differentiation 169-Positive Cells Is Critical for Liver Regeneration

Behnke, K., Zhuang, Y., Xu, H. C., Sundaram, B., Reich, M., Shinde, P. V., Huang, J., Modares, N. F., Tumanov, A. V., Polz, R., et al. (2018) · Hepatology

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 34