Lord, Janet M.

Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation

Buckley, C. D., Pilling, D., Lord, J. M., Akbar, A. N., Scheel-Toellner, D., & Salmon, M. (2001) · Trends in Immunology

Wound Healing and TreatmentsCardiac Fibrosis and Remodeling

Cited by 796

Aging of the innate immune system

Shaw, A. C., Joshi, S., Greenwood, H., Panda, A., & Lord, J. M. (2010) · Current Opinion in Immunology

Immune Response and InflammationImmune responses and vaccinations

Cited by 647

Frailty and sarcopenia: The potential role of an aged immune system

Wilson, D., Jackson, T., Sapey, E., & Lord, J. M. (2017) · Ageing Research Reviews

Nutrition and Health in AgingFrailty in Older Adults

Cited by 573

Human innate immunosenescence: causes and consequences for immunity in old age

Panda, A., Arjona, A., Sapey, E., Bai, F., Fikrig, E., Montgomery, R. R., Lord, J. M., & Shaw, A. C. (2009) · Trends in Immunology

Immune responses and vaccinationsImmune Response and Inflammation

Cited by 502

Can physical activity ameliorate immunosenescence and thereby reduce age-related multi-morbidity?

Duggal, N. A., Niemiro, G., Harridge, S. D. R., Simpson, R. J., & Lord, J. M. (2019) · Nature Reviews Immunology

Exercise and Physiological ResponsesPhysical Activity and Health

Cited by 436

Senescence in innate immune responses: reduced neutrophil phagocytic capacity and CD16 expression in elderly humans

Butcher, S. K., Chahal, H., Nayak, L., Sinclair, A., Henriquez, N. V., Sapey, E., O'Mahony, D., & Lord, J. M. (2001) · Journal of Leukocyte Biology

Neutrophil, Myeloperoxidase and Oxidative MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 436

Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence

Sapey, E., Greenwood, H., Walton, G., Mann, E., Love, A., Aaronson, N., Insall, R. H., Stockley, R. A., & Lord, J. M. (2014) · Blood

Neutrophil, Myeloperoxidase and Oxidative MechanismsInflammation biomarkers and pathways

Cited by 358

The age-related increase in low-grade systemic inflammation (Inflammaging) is not driven by cytomegalovirus infection

Bartlett, D. B., Firth, C. M., Phillips, A. C., Moss, P., Baylis, D., Syddall, H., Sayer, A. A., Cooper, C., & Lord, J. M. (2012) · Aging Cell

Cytomegalovirus and herpesvirus researchGenetics, Aging, and Longevity in Model Organisms

Cited by 278

Major features of immunesenescence, including reduced thymic output, are ameliorated by high levels of physical activity in adulthood

Duggal, N. A., Pollock, R. D., Lazarus, N. R., Harridge, S., & Lord, J. M. (2018) · Aging Cell

T-cell and B-cell ImmunologyExercise and Physiological Responses

Cited by 261

The cortisol stress response induced by surgery: A systematic review and meta‐analysis

Prete, A., Yan, Q., Al‐Tarrah, K., Akturk, H. K., Prokop, L. J., Alahdab, F., Foster, M. A., Lord, J. M., Karavitaki, N., Wass, J. A., et al. (2018) · Clinical Endocrinology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 192

Dehydroepiandrosterone as a regulator of immune cell function

Hazeldine, J., Arlt, W., & Lord, J. M. (2010) · The Journal of Steroid Biochemistry and Molecular Biology

Adrenal Hormones and DisordersHormonal and reproductive studies

Cited by 173

Expression of protein kinase C isoenzymes in colorectal cancer tissue and their differential activation by different bile acids

Pongracz, J., Clark, P., Neoptolemos, J. P., & Lord, J. M. (1995) · International Journal of Cancer

Protein Kinase Regulation and GTPase SignalingCancer, Lipids, and Metabolism

Cited by 137

Stress, ageing and their influence on functional, cellular and molecular aspects of the immune system

Vitlic, A., Lord, J. M., & Phillips, A. C. (2014) · AGE

Stress Responses and CortisolCancer, Stress, Anesthesia, and Immune Response

Cited by 123

Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses

Alsaleh, G., Panse, I., Swadling, L., Zhang, H., Richter, F. C., Meyer, A., Lord, J., Barnes, E., Klenerman, P., Green, C., et al. (2020) · eLife

Autophagy in Disease and TherapyT-cell and B-cell Immunology

Cited by 120

Primary adrenal insufficiency is associated with impaired natural killer cell function: a potential link to increased mortality

Bancos, I., Hazeldine, J., Chortis, V., Hampson, P., Taylor, A. E., Lord, J. M., & Arlt, W. (2017) · European Journal of Endocrinology

Adrenal Hormones and DisordersImmune Cell Function and Interaction

Cited by 110

Innate immunesenescence: underlying mechanisms and clinical relevance

Hazeldine, J., & Lord, J. M. (2015) · Biogerontology

Immune Response and InflammationImmune responses and vaccinations

Cited by 104

Predicting outcome in older hospital patients with delirium: a systematic literature review: Predicting outcome in delirium

Jackson, T. A., Wilson, D., Richardson, S., & Lord, J. M. (2016) · International Journal of Geriatric Psychiatry

Intensive Care Unit Cognitive DisordersAlcoholism and Thiamine Deficiency

Cited by 100

Prevention of adrenal crisis: cortisol responses to major stress compared to stress dose hydrocortisone delivery

Prete, A., Taylor, A. E., Bancos, I., Smith, D. J., Foster, M. A., Kohler, S., Fazal-Sanderson, V., Komninos, J., O’Neil, D. M., Vassiliadi, D. A., et al. (2020) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 96

Tackling immunosenescence to improve COVID-19 outcomes and vaccine response in older adults

Cox, L. S., Bellantuono, I., Lord, J. M., Sapey, E., Mannick, J. B., Partridge, L., Gordon, A. L., Steves, C. J., & Witham, M. D. (2020) · The Lancet Healthy Longevity

Immune responses and vaccinationsSARS-CoV-2 and COVID-19 Research

Cited by 73

Neutrophil function and cortisol: DHEAS ratio in bereaved older adults

Khanfer, R., Lord, J. M., & Phillips, A. C. (2011) · Brain, Behavior, and Immunity

Grief, Bereavement, and Mental HealthStress Responses and Cortisol

Cited by 72

Undiagnosed long-term cognitive impairment in acutely hospitalised older medical patients with delirium: a prospective cohort study

Jackson, T. A., MacLullich, A. M. J., Gladman, J. R. F., Lord, J. M., & Sheehan, B. (2016) · Age and Ageing

Dementia and Cognitive Impairment ResearchIntensive Care Unit Cognitive Disorders

Cited by 66

Depressive symptoms are associated with reduced neutrophil function in hip fracture patients

Duggal, N. A., Upton, J., Phillips, A. C., Hampson, P., & Lord, J. M. (2013) · Brain, Behavior, and Immunity

Stress Responses and CortisolHip and Femur Fractures

Cited by 39

Altered human neutrophil function in response to acute psychological stress

Khanfer, R., Phillips, A. C., Carroll, D., & Lord, J. M. (2010) · Psychosomatic Medicine

Stress Responses and CortisolCancer, Stress, Anesthesia, and Immune Response

Cited by 37

Prevention of adrenal crisis in stress (The PACS Study): serum cortisol during elective surgery, acute trauma and sepsis in comparison to 'stress dose' hydrocortisone administration in adrenal insufficiency

Taylor, A., Karavitaki, N., Smith, D., Bancos, I., Foster, M., Meier, S., O'Neil, D., Komninos, J., Vassiliadi, D., Mowatt, C., et al. (2015) · Endocrine Abstracts

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 1