Atarashi, Koji

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

Furusawa, Y., Obata, Y., Fukuda, S., Endo, T. A., Nakato, G., Takahashi, D., Nakanishi, Y., Uetake, C., Kato, K., Kato, T., et al. (2013) · Nature

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 5,549

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivanov, I. I., Atarashi, K., Manel, N., Brodie, E. L., Shima, T., Karaoz, U., Wei, D., Goldfarb, K. C., Santee, C. A., Lynch, S. V., et al. (2009) · Cell

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 4,554

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

Atarashi, K., Tanoue, T., Shima, T., Imaoka, A., Kuwahara, T., Momose, Y., Cheng, G., Yamasaki, S., Saito, T., Ohba, Y., et al. (2011) · Science

T-cell and B-cell ImmunologyGut microbiota and health

Cited by 3,752

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

Atarashi, K., Tanoue, T., Oshima, K., Suda, W., Nagano, Y., Nishikawa, H., Fukuda, S., Saito, T., Narushima, S., Hase, K., et al. (2013) · Nature

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 2,872

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

Yoshimoto, S., Loo, T. M., Atarashi, K., Kanda, H., Sato, S., Oyadomari, S., Iwakura, Y., Oshima, K., Morita, H., Hattori, M., et al. (2013) · Nature

Gut microbiota and healthTelomeres, Telomerase, and Senescence

Cited by 2,219

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

Tanoue, T., Morita, S., Plichta, D. R., Skelly, A. N., Suda, W., Sugiura, Y., Narushima, S., Vlamakis, H., Motoo, I., Sugita, K., et al. (2019) · Nature

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 1,145

ATP drives lamina propria TH17 cell differentiation

Atarashi, K., Nishimura, J., Shima, T., Umesaki, Y., Yamamoto, M., Onoue, M., Yagita, H., Ishii, N., Evans, R., Honda, K., et al. (2008) · Nature

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 1,089

Th17 cell induction by adhesion of microbes to intestinal epithelial cells

Atarashi, K., Tanoue, T., Ando, M., Kamada, N., Nagano, Y., Narushima, S., Suda, W., Imaoka, A., Setoyama, H., Nagamori, T., et al. (2015) · Cell

Gut microbiota and healthPsoriasis: Treatment and Pathogenesis

Cited by 1,071

Ectopic colonization of oral bacteria in the intestine drives T H 1 cell induction and inflammation

Atarashi, K., Suda, W., Luo, C., Kawaguchi, T., Motoo, I., Narushima, S., Kiguchi, Y., Yasuma, K., Watanabe, E., Tanoue, T., et al. (2017) · Science

Gut microbiota and healthInflammatory Bowel Disease

Cited by 957

Two FOXP3+CD4+ T cell subpopulations distinctly control the prognosis of colorectal cancers

Saito, T., Nishikawa, H., Wada, H., Nagano, Y., Sugiyama, D., Atarashi, K., Maeda, Y., Hamaguchi, M., Ohkura, N., Sato, E., et al. (2016) · Nature Medicine

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 871

The microbiota regulates type 2 immunity through RORγt + T cells

Ohnmacht, C., Park, J.-H., Cording, S., Wing, J. B., Atarashi, K., Obata, Y., Gaboriau-Routhiau, V., Marques, R., Dulauroy, S., Fedoseeva, M., et al. (2015) · Science

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 863

Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring

Kim, S., Kim, H., Yim, Y. S., Ha, S., Atarashi, K., Tan, T. G., Longman, R. S., Honda, K., Littman, D. R., Choi, G. B., et al. (2017) · Nature

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 678

Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians

Sato, Y., Atarashi, K., Plichta, D. R., Arai, Y., Sasajima, S., Kearney, S. M., Suda, W., Takeshita, K., Sasaki, T., Okamoto, S., et al. (2021) · Nature

Gut microbiota and healthSteroid Chemistry and Biochemistry

Cited by 632

Development and maintenance of intestinal regulatory T cells

Tanoue, T., Atarashi, K., & Honda, K. (2016) · Nature Reviews Immunology

T-cell and B-cell ImmunologyGut microbiota and health

Cited by 553

Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation

Federici, S., Kredo-Russo, S., Valdés-Mas, R., Kviatcovsky, D., Weinstock, E., Matiuhin, Y., Silberberg, Y., Atarashi, K., Furuichi, M., Oka, A., et al. (2022) · Cell

Bacteriophages and microbial interactionsGut microbiota and health

Cited by 542

Foxp3+ T Cells Regulate Immunoglobulin A Selection and Facilitate Diversification of Bacterial Species Responsible for Immune Homeostasis

Kawamoto, S., Maruya, M., Kato, L. M., Suda, W., Atarashi, K., Doi, Y., Tsutsui, Y., Qin, H., Honda, K., Okada, T., et al. (2014) · Immunity

T-cell and B-cell ImmunologyGut microbiota and health

Cited by 531

Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis

Nakamoto, N., Sasaki, N., Aoki, R., Miyamoto, K., Suda, W., Teratani, T., Suzuki, T., Koda, Y., Chu, P.-S., Taniki, N., et al. (2019) · Nature Microbiology

Liver Diseases and ImmunityGut microbiota and health

Cited by 425

Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II–restricted cytotoxic T lymphocytes

Mucida, D., Husain, M. M., Muroi, S., van Wijk, F., Shinnakasu, R., Naoe, Y., Reis, B. S., Huang, Y., Lambolez, F., Docherty, M., et al. (2013) · Nature Immunology

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 376

Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome

Kawano, Y., Edwards, M., Huang, Y., Bilate, A. M., Araujo, L. P., Tanoue, T., Atarashi, K., Ladinsky, M. S., Reiner, S. L., Wang, H. H., et al. (2022) · Cell

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 349

Characterization of the 17 strains of regulatory T cell-inducing human-derived Clostridia

Narushima, S., Sugiura, Y., Oshima, K., Atarashi, K., Hattori, M., Suematsu, M., & Honda, K. (2014) · Gut Microbes

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 210

Periportal macrophages protect against commensal-driven liver inflammation

Miyamoto, Y., Kikuta, J., Matsui, T., Hasegawa, T., Fujii, K., Okuzaki, D., Liu, Y.-C., Yoshioka, T., Seno, S., Motooka, D., et al. (2024) · Nature

Liver Diseases and ImmunityLiver physiology and pathology

Cited by 135

Identification of trypsin-degrading commensals in the large intestine

Li, Y., Watanabe, E., Kawashima, Y., Plichta, D. R., Wang, Z., Ujike, M., Ang, Q. Y., Wu, R., Furuichi, M., Takeshita, K., et al. (2022) · Nature

Gut microbiota and healthEscherichia coli research studies

Cited by 106

Identification of commensals and molecular components mediating trypsin degradation in the large intestine

Honda, K., Atarashi, K., Sasajima, S., Wang, Z., Nishiyama, K., Matsunaga, T., Zhang, X., Olle, B., Norman, J., Suda, W., et al. (2022) · Nature

Gut microbiota and healthEscherichia coli research studies

Cited by 106

Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease

Valdés-Mas, R., Leshem, A., Zheng, D., Cohen, Y., Kern, L., Zmora, N., He, Y., Katina, C., Eliyahu-Miller, S., Yosef-Hevroni, T., et al. (2025) · Cell

Gut microbiota and healthInflammatory Bowel Disease

Cited by 89