Goedeke, Leigh

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

Rayner, K. J., Esau, C. C., Hussain, F. N., McDaniel, A. L., Marshall, S. M., van Gils, J. M., Ray, T. D., Sheedy, F. J., Goedeke, L., Liu, X., et al. (2011) · Nature

Cholesterol and Lipid MetabolismMicroRNA in disease regulation

Cited by 706

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

Dávalos, A., Goedeke, L., Smibert, P., Ramírez, C. M., Warrier, N. P., Andreo, U., Cirera-Salinas, D., Rayner, K., Suresh, U., Pastor-Pareja, J. C., et al. (2011) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationCholesterol and Lipid Metabolism

Cited by 670

MicroRNAs in Metabolic Disease

Fernández-Hernando, C., Ramírez, C. M., Goedeke, L., & Suárez, Y. (2013) · Arteriosclerosis, Thrombosis, and Vascular Biology

MicroRNA in disease regulationCholesterol and Lipid Metabolism

Cited by 257

MicroRNA-758 Regulates Cholesterol Efflux Through Posttranscriptional Repression of ATP-Binding Cassette Transporter A1

Ramirez, C. M., Dávalos, A., Goedeke, L., Salerno, A. G., Warrier, N., Cirera-Salinas, D., Suárez, Y., & Fernández-Hernando, C. (2011) · Arteriosclerosis, Thrombosis, and Vascular Biology

Cholesterol and Lipid MetabolismMicroRNA in disease regulation

Cited by 242

Control of Cholesterol Metabolism and Plasma High-Density Lipoprotein Levels by microRNA-144

Ramírez, C. M., Rotllan, N., Vlassov, A. V., Dávalos, A., Li, M., Goedeke, L., Aranda, J. F., Cirera-Salinas, D., Araldi, E., Salerno, A., et al. (2013) · Circulation Research

Cholesterol and Lipid MetabolismMicroRNA in disease regulation

Cited by 217

Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis

Perry, R. J., Zhang, D., Guerra, M. T., Brill, A. L., Goedeke, L., Nasiri, A. R., Rabin-Court, A., Wang, Y., Peng, L., Dufour, S., et al. (2020) · Nature

Metabolism, Diabetes, and CancerPancreatic function and diabetes

Cited by 186

MicroRNA 33 Regulates Glucose Metabolism

Ramírez, C. M., Goedeke, L., Rotllan, N., Yoon, J.-H., Cirera-Salinas, D., Mattison, J. A., Suárez, Y., de Cabo, R., Gorospe, M., & Fernández-Hernando, C. (2013) · Molecular and Cellular Biology

MicroRNA in disease regulationMetabolism, Diabetes, and Cancer

Cited by 154

Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice

Goedeke, L., Salerno, A., Ramírez, C. M., Guo, L., Allen, R. M., Yin, X., Langley, S. R., Esau, C., Wanschel, A., Fisher, E. A., et al. (2014) · EMBO Molecular Medicine

Cholesterol and Lipid MetabolismMicroRNA in disease regulation

Cited by 145

A Regulatory Role for MicroRNA 33* in Controlling Lipid Metabolism Gene Expression

Goedeke, L., Vales-Lara, F. M., Fenstermaker, M., Cirera-Salinas, D., Chamorro-Jorganes, A., Ramírez, C. M., Mattison, J. A., de Cabo, R., Suárez, Y., & Fernández-Hernando, C. (2013) · Molecular and Cellular Biology

MicroRNA in disease regulationCholesterol and Lipid Metabolism

Cited by 140

Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance

Price, N. L., Singh, A. K., Rotllan, N., Goedeke, L., Wing, A., Canfrán-Duque, A., Diaz-Ruiz, A., Araldi, E., Baldán, Á., Camporez, J.-P., et al. (2018) · Cell Reports

MicroRNA in disease regulationAdipokines, Inflammation, and Metabolic Diseases

Cited by 110

MicroRNA 7 Impairs Insulin Signaling and Regulates A β Levels through Posttranscriptional Regulation of the Insulin Receptor Substrate 2, Insulin Receptor, Insulin-Degrading Enzyme, and Liver X Receptor Pathway

Fernández-de Frutos, M., Galán-Chilet, I., Goedeke, L., Kim, B., Pardo-Marqués, V., Pérez-García, A., Herrero, J. I., Fernández-Hernando, C., Kim, J., & Ramírez, C. M. (2019) · Molecular and Cellular Biology

MicroRNA in disease regulationAdipokines, Inflammation, and Metabolic Diseases

Cited by 82

Loss of hepatic miR-33 improves metabolic homeostasis and liver function without altering body weight or atherosclerosis

Price, N. L., Zhang, X., Fernández-Tussy, P., Singh, A. K., Burnap, S. A., Rotllan, N., Goedeke, L., Sun, J., Canfrán-Duque, A., Aryal, B., et al. (2021) · Proceedings of the National Academy of Sciences

Cholesterol and Lipid MetabolismMicroRNA in disease regulation

Cited by 50

miR‐33 in cardiometabolic diseases: lessons learned from novel animal models and approaches

Price, N. L., Goedeke, L., Suárez, Y., & Fernández‐Hernando, C. (2021) · EMBO Molecular Medicine

MicroRNA in disease regulationCholesterol and Lipid Metabolism

Cited by 36

miR-33 deletion in hepatocytes attenuates MASLD-MASH-HCC progression

Fernández-Tussy, P., Cardelo, M. P., Zhang, H., Sun, J., Price, N. L., Boutagy, N. E., Goedeke, L., Cadena-Sandoval, M., Xirouchaki, C. E., Brown, W., et al. (2024) · JCI Insight

Liver Disease Diagnosis and TreatmentMicroRNA in disease regulation

Cited by 21

Tet2 and Jak2 clonal hematopoiesis do not modify murine tauopathy

Gaebel, L., Gerhardt, T., Khamhoung, A., Huynh, P., Heiser, M., Brisnovali, N. F., Jacob, W., Yates, A. G., Douglas, A., Fidler, T., et al. (2026) · Journal of Alzheimer’s Disease

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

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