Hodson, David J.

Beta cell hubs dictate pancreatic islet responses to glucose

Johnston, N. R., Mitchell, R. K., Haythorne, E., Pessoa, M. P., Semplici, F., Ferrer, J., Piemonti, L., Marchetti, P., Bugliani, M., Bosco, D., et al. (2016) · Cell Metabolism

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 454

Rapid sensing of circulating ghrelin by hypothalamic appetite-modifying neurons

Schaeffer, M., Langlet, F., Lafont, C., Molino, F., Hodson, D. J., Roux, T., Lamarque, L., Verdié, P., Bourrier, E., Dehouck, B., et al. (2013) · Proceedings of the National Academy of Sciences

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 325

Revisiting the Complexity of GLP-1 Action from Sites of Synthesis to Receptor Activation

McLean, B. A., Wong, C. K., Campbell, J. E., Hodson, D. J., Trapp, S., & Drucker, D. J. (2021) · Endocrine Reviews

Diabetes Treatment and ManagementRegulation of Appetite and Obesity

Cited by 289

Lipotoxicity disrupts incretin-regulated human β cell connectivity

Hodson, D. J., Mitchell, R. K., Bellomo, E. A., Sun, G., Vinet, L., Meda, P., Li, D., Li, W.-H., Bugliani, M., Marchetti, P., et al. (2013) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 210

ADCY5 Couples Glucose to Insulin Secretion in Human Islets

Hodson, D. J., Mitchell, R. K., Marselli, L., Pullen, T. J., Gimeno Brias, S., Semplici, F., Everett, K. L., Cooper, D. M. F., Bugliani, M., Marchetti, P., et al. (2014) · Diabetes

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 147

GLP1R Attenuates Sympathetic Response to High Glucose via Carotid Body Inhibition

Pauza, A. G., Thakkar, P., Tasic, T., Felippe, I., Bishop, P., Greenwood, M. P., Rysevaite-Kyguoliene, K., Ast, J., Broichhagen, J., Hodson, D. J., et al. (2022) · Circulation Research

Neuroscience of respiration and sleepHeart Rate Variability and Autonomic Control

Cited by 106

Androgen Excess in Pancreatic β Cells and Neurons Predisposes Female Mice to Type 2 Diabetes

Navarro, G., Allard, C., Morford, J. J., Xu, W., Liu, S., Molinas, A. J. R., Butcher, S. M., Fine, N. H. F., Blandino-Rosano, M., Sure, V. N., et al. (2018) · JCI Insight

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 80

Anorectic and aversive effects of GLP-1 receptor agonism are mediated by brainstem cholecystokinin neurons, and modulated by GIP receptor activation

Costa, A., Ai, M., Nunn, N., Culotta, I., Hunter, J., Boudjadja, M. B., Valencia-Torres, L., Aviello, G., Hodson, D. J., Snider, B. M., et al. (2022) · Molecular Metabolism

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 79

Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding

Adriaenssens, A., Broichhagen, J., de Bray, A., Ast, J., Hasib, A., Jones, B., Tomas, A., Burgos, N. F., Woodward, O., Lewis, J., et al. (2023) · JCI Insight

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 77

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

Fine, N. H. F., Doig, C. L., Elhassan, Y. S., Vierra, N. C., Marchetti, P., Bugliani, M., Nano, R., Piemonti, L., Rutter, G. A., Jacobson, D. A., et al. (2018) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 61

Reagents and models for detecting endogenous GLP1R and GIPR

Ast, J., Broichhagen, J., & Hodson, D. J. (2021) · EBioMedicine

Diabetes Treatment and ManagementReceptor Mechanisms and Signaling

Cited by 40

GLP1R and GIPR expression and signaling in pancreatic alpha cells, beta cells and delta cells

Shilleh, A. H., Viloria, K., Broichhagen, J., Campbell, J. E., & Hodson, D. J. (2024) · Peptides

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 39

The Influence of Peptide Context on Signaling and Trafficking of Glucagon-like Peptide-1 Receptor Biased Agonists

Fang, Z., Chen, S., Pickford, P., Broichhagen, J., Hodson, D. J., Corrêa, I. R., Kumar, S., Görlitz, F., Dunsby, C., French, P. M. W., et al. (2020) · ACS Pharmacology & Translational Science

Receptor Mechanisms and SignalingDiabetes Treatment and Management

Cited by 38

A neuronal circuit driven by GLP-1 in the olfactory bulb regulates insulin secretion

Montaner, M., Denom, J., Simon, V., Jiang, W., Holt, M. K., Brierley, D. I., Rouch, C., Foppen, E., Kassis, N., Jarriault, D., et al. (2024) · Nature Communications

Pancreatic function and diabetesRegulation of Appetite and Obesity

Cited by 36

Reassessment of antibody-based detection of the murine T cell GLP-1 receptor

Wong, C. K., Yusta, B., Tong, J. C. L., Broichhagen, J., Hodson, D. J., & Drucker, D. J. (2025) · Cell Metabolism

Diabetes Treatment and ManagementReceptor Mechanisms and Signaling

Cited by 14