Harris, Curtis C.

p53 Mutations in Human Cancers

Hollstein, M., Sidransky, D., Vogelstein, B., & Harris, C. C. (1991) · Science

Cancer-related Molecular PathwaysCancer Genomics and Diagnostics

Cited by 8,018

A microRNA expression signature of human solid tumors defines cancer gene targets

Volinia, S., Calin, G. A., Liu, C.-G., Ambs, S., Cimmino, A., Petrocca, F., Visone, R., Iorio, M., Roldo, C., Ferracin, M., et al. (2006) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 5,697

Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

Yanaihara, N., Caplen, N., Bowman, E., Seike, M., Kumamoto, K., Yi, M., Stephens, R. M., Okamoto, A., Yokota, J., Tanaka, T., et al. (2006) · Cancer Cell

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 3,023

Radical causes of cancer

Hussain, S. P., Hofseth, L. J., & Harris, C. C. (2003) · Nature Reviews Cancer

Redox biology and oxidative stressCancer and biochemical research

Cited by 1,690

The IARC TP53 database: new online mutation analysis and recommendations to users

Olivier, M., Eeles, R., Hollstein, M., Khan, M. A., Harris, C. C., & Hainaut, P. (2002) · Human Mutation

Cancer-related Molecular PathwaysCancer Genomics and Diagnostics

Cited by 1,248

The chemical biology of nitric oxide: Implications in cellular signaling

Thomas, D. D., Ridnour, L. A., Isenberg, J. S., Flores-Santana, W., Switzer, C. H., Donzelli, S., Hussain, P., Vecoli, C., Paolocci, N., Ambs, S., et al. (2008) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 975

KIF5B-RET fusions in lung adenocarcinoma

Kohno, T., Ichikawa, H., Totoki, Y., Yasuda, K., Hiramoto, M., Nammo, T., Sakamoto, H., Tsuta, K., Furuta, K., Shimada, Y., et al. (2012) · Nature Medicine

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

Cited by 834

Fusobacterium nucleatum and T Cells in Colorectal Carcinoma

Mima, K., Sukawa, Y., Nishihara, R., Qian, Z. R., Yamauchi, M., Inamura, K., Kim, S. A., Masuda, A., Nowak, J. A., Nosho, K., et al. (2015) · JAMA Oncology

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 669

GADD45 induction of a G 2 /M cell cycle checkpoint

Wang, X. W., Zhan, Q., Coursen, J. D., Khan, M. A., Kontny, H. U., Yu, L., Hollander, M. C., O’Connor, P. M., Fornace, A. J., & Harris, C. C. (1999) · Proceedings of the National Academy of Sciences

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 634

Detectable clonal mosaicism and its relationship to aging and cancer

Jacobs, K. B., Yeager, M., Zhou, W., Wacholder, S., Wang, Z., Rodriguez-Santiago, B., Hutchinson, A., Deng, X., Liu, C., Horner, M.-J., et al. (2012) · Nature Genetics

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 589

p53: traffic cop at the crossroads of DNA repair and recombination

Sengupta, S., & Harris, C. C. (2005) · Nature Reviews Molecular Cell Biology

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 544

MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers

Seike, M., Goto, A., Okano, T., Bowman, E. D., Schetter, A. J., Horikawa, I., Mathe, E. A., Jen, J., Yang, P., Sugimura, H., et al. (2009) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationLung Cancer Treatments and Mutations

Cited by 500

Interaction between the microbiome and TP53 in human lung cancer

Greathouse, K. L., White, J. R., Vargas, A. J., Bliskovsky, V. V., Beck, J. A., von Muhlinen, N., Polley, E. C., Bowman, E. D., Khan, M. A., Robles, A. I., et al. (2018) · Genome Biology

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 446

Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma

Chaisaingmongkol, J., Budhu, A., Dang, H., Rabibhadana, S., Pupacdi, B., Kwon, S. M., Forgues, M., Pomyen, Y., Bhudhisawasdi, V., Lertprasertsuke, N., et al. (2017) · Cancer Cell

Cholangiocarcinoma and Gallbladder Cancer StudiesHepatocellular Carcinoma Treatment and Prognosis

Cited by 434

Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

Hofseth, L. J., Saito, S., Hussain, S. P., Espey, M. G., Miranda, K. M., Araki, Y., Jhappan, C., Higashimoto, Y., He, P., Linke, S. P., et al. (2003) · Proceedings of the National Academy of Sciences

Cancer-related Molecular PathwaysRedox biology and oxidative stress

Cited by 355

p53 isoforms Δ133p53 and p53β are endogenous regulators of replicative cellular senescence

Fujita, K., Mondal, A. M., Horikawa, I., Nguyen, G. H., Kumamoto, K., Sohn, J. J., Bowman, E. D., Mathe, E. A., Schetter, A. J., Pine, S. R., et al. (2009) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 336

Hypoxic inducible factor 1α, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide

Thomas, D. D., Espey, M. G., Ridnour, L. A., Hofseth, L. J., Mancardi, D., Harris, C. C., & Wink, D. A. (2004) · Proceedings of the National Academy of Sciences

Cancer, Hypoxia, and MetabolismNitric Oxide and Endothelin Effects

Cited by 289

Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression

Ambs, S., Hussain, S. P., & Harris, C. C. (1997) · The FASEB Journal

Cancer-related Molecular PathwaysNitric Oxide and Endothelin Effects

Cited by 233

Evolutionary conservation and somatic mutation hotspot maps of p53: correlation with p53 protein structural and functional features

Walker, D. R., Bond, J. P., Tarone, R. E., Harris, C. C., Makalowski, W., Boguski, M. S., & Greenblatt, M. S. (1999) · Oncogene

Cancer-related Molecular PathwaysCancer Genomics and Diagnostics

Cited by 198

Relationship between p53 mutations and inducible nitric oxide synthase expression in human colorectal cancer

Ambs, S., Bennett, W. P., Merriam, W. G., Ogunfusika, M. O., Oser, S. M., Harrington, A. M., Shields, P. G., Felley-Bosco, E., Hussain, S. P., & Harris, C. C. (1999) · JNCI Journal of the National Cancer Institute

Nitric Oxide and Endothelin EffectsCancer-related Molecular Pathways

Cited by 166

Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence

Tang, Y., Horikawa, I., Ajiro, M., Robles, A. I., Fujita, K., Mondal, A. M., Stauffer, J. K., Zheng, Z.-M., & Harris, C. C. (2013) · Oncogene

RNA Research and SplicingTelomeres, Telomerase, and Senescence

Cited by 165

p53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes

Mondal, A. M., Horikawa, I., Pine, S. R., Fujita, K., Morgan, K. M., Vera, E., Mazur, S. J., Appella, E., Vojtesek, B., Blasco, M. A., et al. (2013) · Journal of Clinical Investigation

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 164

Superoxide fluxes limit nitric oxide-induced signaling

Thomas, D. D., Ridnour, L. A., Espey, M. G., Donzelli, S., Ambs, S., Hussain, S. P., Harris, C. C., DeGraff, W., Roberts, D. D., Mitchell, J. B., et al. (2006) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 121

Radiation-induced astrocyte senescence is rescued by Δ133p53

Turnquist, C., Beck, J. A., Horikawa, I., Obiorah, I. E., Von Muhlinen, N., Vojtesek, B., Lane, D. P., Grunseich, C., Chahine, J. J., Ames, H. M., et al. (2019) · Neuro-Oncology

Telomeres, Telomerase, and SenescenceEffects of Radiation Exposure

Cited by 118