Singer, Robert H.

Visualization of Single RNA Transcripts in Situ

Femino, A. M., Fay, F. S., Fogarty, K., & Singer, R. H. (1998) · Science

Advanced Fluorescence Microscopy TechniquesRNA Research and Splicing

Cited by 1,504

Transcriptional Pulsing of a Developmental Gene

Chubb, J. R., Trcek, T., Shenoy, S. M., & Singer, R. H. (2006) · Current Biology

Gene Regulatory Network AnalysisGenomics and Chromatin Dynamics

Cited by 714

From Silencing to Gene Expression

Janicki, S. M., Tsukamoto, T., Salghetti, S. E., Tansey, W. P., Sachidanandam, R., Prasanth, K. V., Ried, T., Shav-Tal, Y., Bertrand, E., Singer, R. H., et al. (2004) · Cell

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 704

Single-RNA counting reveals alternative modes of gene expression in yeast

Zenklusen, D., Larson, D. R., & Singer, R. H. (2008) · Nature Structural & Molecular Biology

Gene Regulatory Network AnalysisGenomics and Chromatin Dynamics

Cited by 684

Real-Time Observation of Transcription Initiation and Elongation on an Endogenous Yeast Gene

Larson, D. R., Zenklusen, D., Wu, B., Chao, J. A., & Singer, R. H. (2011) · Science

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 680

In vivo dynamics of RNA polymerase II transcription

Darzacq, X., Shav-Tal, Y., de Turris, V., Brody, Y., Shenoy, S. M., Phair, R. D., & Singer, R. H. (2007) · Nature Structural & Molecular Biology

Genomics and Chromatin DynamicsRNA Research and Splicing

Cited by 665

Single-Cell Gene Expression Profiling

Levsky, J. M., Shenoy, S. M., Pezo, R. C., & Singer, R. H. (2002) · Science

Single-cell and spatial transcriptomicsAdvanced Fluorescence Microscopy Techniques

Cited by 526

A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome

Dictenberg, J. B., Swanger, S. A., Antar, L. N., Singer, R. H., & Bassell, G. J. (2008) · Developmental Cell

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 511

Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse

Greenberg, R. A., Chin, L., Femino, A., Lee, K.-H., Gottlieb, G. J., Singer, R. H., Greider, C. W., & DePinho, R. A. (1999) · Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 367

Eukaryotic transcriptional dynamics: from single molecules to cell populations

Coulon, A., Chow, C. C., Singer, R. H., & Larson, D. R. (2013) · Nature Reviews Genetics

Gene Regulatory Network AnalysisGenomics and Chromatin Dynamics

Cited by 309

Single-molecule analysis of gene expression using two-color RNA labeling in live yeast

Hocine, S., Raymond, P., Zenklusen, D., Chao, J. A., & Singer, R. H. (2013) · Nature Methods

Advanced Fluorescence Microscopy TechniquesRNA Research and Splicing

Cited by 297

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

Carvajal, L. A., Neriah, D. B., Senecal, A., Benard, L., Thiruthuvanathan, V., Yatsenko, T., Narayanagari, S.-R., Wheat, J. C., Todorova, T. I., Mitchell, K., et al. (2018) · Science Translational Medicine

Cancer-related Molecular PathwaysAcute Myeloid Leukemia Research

Cited by 249

β-Actin Messenger RNA Localization and Protein Synthesis Augment Cell Motility

Kislauskis, E. H., Zhu, X.-C., & Singer, R. H. (1997) · The Journal of Cell Biology

RNA Research and SplicingCellular Mechanics and Interactions

Cited by 230

The Survival of Motor Neuron (SMN) Protein Interacts with the mRNA-Binding Protein HuD and Regulates Localization of Poly(A) mRNA in Primary Motor Neuron Axons

Fallini, C., Zhang, H., Su, Y., Silani, V., Singer, R. H., Rossoll, W., & Bassell, G. J. (2011) · The Journal of Neuroscience

Neurogenetic and Muscular Disorders ResearchRNA Research and Splicing

Cited by 221

The life of an mRNA in space and time

Ben-Ari, Y., Brody, Y., Kinor, N., Mor, A., Tsukamoto, T., Spector, D. L., Singer, R. H., & Shav-Tal, Y. (2010) · Journal of Cell Science

RNA Research and SplicingGenomics and Chromatin Dynamics

Cited by 133

Neurotransmitter identity is acquired in a lineage-restricted manner in the Drosophila CNS

Lacin, H., Chen, H.-M., Long, X., Singer, R. H., Lee, T., & Truman, J. W. (2019) · eLife

Neurobiology and Insect Physiology ResearchDevelopmental Biology and Gene Regulation

Cited by 131

Single-molecule imaging of transcription dynamics in somatic stem cells

Wheat, J. C., Sella, Y., Willcockson, M., Skoultchi, A. I., Bergman, A., Singer, R. H., & Steidl, U. (2020) · Nature

Gene Regulatory Network AnalysisSingle-cell and spatial transcriptomics

Cited by 88

The Structural Basis for RNA Selectivity by the IMP Family of RNA-Binding Proteins

Biswas, J., Patel, V. L., Bhaskar, V., Chao, J. A., Singer, R. H., & Eliscovich, C. (2019) · Nature Communications

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 84

Developmental timing in Dictyostelium is regulated by the Set1 histone methyltransferase

Chubb, J. R., Bloomfield, G., Xu, Q., Kaller, M., Ivens, A., Skelton, J., Turner, B. M., Nellen, W., Shaulsky, G., Kay, R. R., et al. (2006) · Developmental Biology

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 41