Haydar, Tarik F.

Reduced Apoptosis and Cytochrome c–Mediated Caspase Activation in Mice Lacking Caspase 9

Kuida, K., Haydar, T. F., Kuan, C.-Y., Gu, Y., Taya, C., Karasuyama, H., Su, M. S.-S., Rakic, P., & Flavell, R. A. (1998) · Cell

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 1,643

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

Asai, H., Ikezu, S., Tsunoda, S., Medalla, M., Luebke, J., Haydar, T., Wolozin, B., Butovsky, O., Kügler, S., & Ikezu, T. (2015) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,591

Four-Dimensional Migratory Coordinates of GABAergic Interneurons in the Developing Mouse Cortex

Ang, E. S. B. C., Haydar, T. F., Gluncic, V., & Rakic, P. (2003) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 282

Olig1 and Olig2 triplication causes developmental brain defects in down syndrome.

Chakrabarti, L., Best, T. K., Cramer, N. P., Carney, R. S. E., Isaac, J. T. R., Galdzicki, Z., & Haydar, T. F. (2010) · Nature Neuroscience

Down syndrome and intellectual disability researchNeurogenesis and neuroplasticity mechanisms

Cited by 258

Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination

Olmos-Serrano, J. L., Kang, H. J., Tyler, W. A., Silbereis, J. C., Cheng, F., Zhu, Y., Pletikos, M., Jankovic-Rapan, L., Cramer, N. P., Galdzicki, Z., et al. (2016) · Neuron

Down syndrome and intellectual disability researchNeurogenesis and neuroplasticity mechanisms

Cited by 239

Requirement of the JIP1 scaffold protein for stress-induced JNK activation

Whitmarsh, A. J., Kuan, C.-Y., Kennedy, N. J., Kelkar, N., Haydar, T. F., Mordes, J. P., Appel, M., Rossini, A. A., Jones, S. N., Flavell, R. A., et al. (2001) · Genes & Development

Protein Kinase Regulation and GTPase SignalingNF-κB Signaling Pathways

Cited by 238

Trisomy 21 and early brain development

Haydar, T. F., & Reeves, R. H. (2012) · Trends in Neurosciences

Down syndrome and intellectual disability researchGenetics and Neurodevelopmental Disorders

Cited by 200

Defects in Embryonic Neurogenesis and Initial Synapse Formation in the Forebrain of the Ts65Dn Mouse Model of Down Syndrome

Chakrabarti, L., Galdzicki, Z., & Haydar, T. F. (2007) · The Journal of Neuroscience

Down syndrome and intellectual disability researchNeurogenesis and neuroplasticity mechanisms

Cited by 199

Heterogeneity in Ventricular Zone Neural Precursors Contributes to Neuronal Fate Diversity in the Postnatal Neocortex

Stancik, E. K., Navarro-Quiroga, I., Sellke, R., & Haydar, T. F. (2010) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 186

Lifespan analysis of brain development, gene expression and behavioral phenotypes in the Ts1Cje, Ts65Dn and Dp(16)1/Yey mouse models of Down syndrome

Aziz, N. M., Guedj, F., Pennings, J. L. A., Olmos-Serrano, J. L., Siegel, A., Haydar, T. F., & Bianchi, D. W. (2018) · Disease Models & Mechanisms

Down syndrome and intellectual disability researchGenetics and Neurodevelopmental Disorders

Cited by 118

Multiplex genetic fate mapping reveals a novel route of neocortical neurogenesis, which is altered in the Ts65Dn mouse model of down syndrome.

Tyler, W. A., & Haydar, T. F. (2013) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 81

Absence of Prenatal Forebrain Defects in the Dp(16)1Yey/+ Mouse Model of down Syndrome.

Goodliffe, J. W., Olmos-Serrano, J. L., Aziz, N. M., Pennings, J. L. A., Guedj, F., Bianchi, D. W., & Haydar, T. F. (2016) · The Journal of Neuroscience

Down syndrome and intellectual disability researchGenetics and Neurodevelopmental Disorders

Cited by 65

Neural precursor lineages specify distinct neocortical pyramidal neuron types.

Tyler, W. A., Medalla, M., Guillamon-Vivancos, T., Luebke, J. I., & Haydar, T. F. (2015) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 60

BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer’s disease

Burke, R. M., Norman, T. A., Haydar, T. F., Slack, B. E., Leeman, S. E., Blusztajn, J. K., & Mellott, T. J. (2013) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsCholinesterase and Neurodegenerative Diseases

Cited by 59

The (Not Necessarily) Convoluted Role of Basal Radial Glia in Cortical Neurogenesis

Hevner, R. F., & Haydar, T. F. (2012) · Cerebral Cortex

Neurogenesis and neuroplasticity mechanismsFetal and Pediatric Neurological Disorders

Cited by 56

Neurodevelopment in Down syndrome: Concordance in humans and models

Klein, J. A., & Haydar, T. F. (2022) · Frontiers in Cellular Neuroscience

Down syndrome and intellectual disability researchGenetics and Neurodevelopmental Disorders

Cited by 47

Longitudinal neuroanatomical and behavioral analyses show phenotypic drift and variability in the Ts65Dn mouse model of down syndrome.

Shaw, P. R., Klein, J. A., Aziz, N. M., & Haydar, T. F. (2020) · Disease Models & Mechanisms

Down syndrome and intellectual disability researchGenetics and Neurodevelopmental Disorders

Cited by 45

Distinct Neocortical Progenitor Lineages Fine-tune Neuronal Diversity in a Layer-specific Manner.

Guillamon-Vivancos, T., Tyler, W. A., Medalla, M., Chang, W. W.-E., Okamoto, M., Haydar, T. F., & Luebke, J. I. (2019) · Cerebral Cortex

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 34

Sonic Hedgehog Pathway Modulation Normalizes Expression of Olig2 in Rostrally Patterned NPCs With Trisomy 21

Klein, J. A., Li, Z., Rampam, S., Cardini, J., Ayoub, A., Shaw, P., Rachubinski, A. L., Espinosa, J. M., Zeldich, E., & Haydar, T. F. (2022) · Frontiers in Cellular Neuroscience

Neurogenesis and neuroplasticity mechanismsDown syndrome and intellectual disability research

Cited by 27

Asynchronous excitatory neuron development in an isogenic cortical spheroid model of Down syndrome

Li, Z., Klein, J. A., Rampam, S., Kurzion, R., Campbell, N. B., Patel, Y., Haydar, T. F., & Zeldich, E. (2022) · Frontiers in Neuroscience

Down syndrome and intellectual disability researchPluripotent Stem Cells Research

Cited by 24

Concurrent Generation of Subplate and Cortical Plate Neurons in Developing Trisomy 16 Mouse Cortex

Cheng, A., Haydar, T. F., Yarowsky, P. J., & Krueger, B. K. (2004) · Developmental Neuroscience

Neurogenesis and neuroplasticity mechanismsDown syndrome and intellectual disability research

Cited by 22

Spatiotemporal development of spinal neuronal and glial populations in the Ts65Dn mouse model of down syndrome.

Aziz, N. M., Klein, J. A., Brady, M. R., Olmos-Serrano, J. L., Gallo, V., & Haydar, T. F. (2019) · Journal of Neurodevelopmental Disorders

Down syndrome and intellectual disability researchNeurogenesis and neuroplasticity mechanisms

Cited by 9