Moreira, Paula I.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Klionsky, D. J., Abeliovich, H., Agostinis, P., Agrawal, D. K., Aliev, G., Askew, D. S., Baba, M., Baehrecke, E. H., Bahr, B. A., Ballabio, A., et al. (2008) · Autophagy

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 2,230

Doxorubicin: The good, the bad and the ugly effect

Carvalho, C., Santos, R., Cardoso, S., Correia, S., Oliveira, P., Santos, M., & Moreira, P. (2009) · Current Medicinal Chemistry

Chemotherapy-induced cardiotoxicity and mitigationBioactive Compounds and Antitumor Agents

Cited by 1,509

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

Cunnane, S. C., Trushina, E., Morland, C., Prigione, A., Casadesus, G., Andrews, Z. B., Beal, M. F., Bergersen, L. H., Brinton, R. D., de la Monte, S., et al. (2020) · Nature Reviews Drug Discovery

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 1,003

Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

Wang, X., Su, B., Siedlak, S. L., Moreira, P. I., Fujioka, H., Wang, Y., Casadesus, G., & Zhu, X. (2008) · Proceedings of the National Academy of Sciences

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 835

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

Finley, L. W. S., Carracedo, A., Lee, J., Souza, A., Egia, A., Zhang, J., Teruya-Feldstein, J., Moreira, P. I., Cardoso, S. M., Clish, C. B., et al. (2011) · Cancer Cell

Cancer, Hypoxia, and MetabolismSirtuins and Resveratrol in Medicine

Cited by 782

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

Moreira, P. I., Carvalho, C., Zhu, X., Smith, M. A., & Perry, G. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 734

Involvement of oxidative stress in Alzheimer disease

Nunomura, A., Castellani, R. J., Zhu, X., Moreira, P. I., Perry, G., & Smith, M. A. (2006) · Journal of Neuropathology and Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 611

Oxidative Stress Signaling in Alzheimers Disease

Su, B., Wang, X., Nunomura, A., Moreira, P., Lee, H.-G., Perry, G., Smith, M., & Zhu, X. (2008) · Current Alzheimer Research

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 344

Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease

Resende, R., Moreira, P. I., Proença, T., Deshpande, A., Busciglio, J., Pereira, C., & Oliveira, C. R. (2008) · Free Radical Biology and Medicine

Alzheimer's disease research and treatmentsAntioxidant Activity and Oxidative Stress

Cited by 343

Ribosomal RNA in Alzheimer Disease Is Oxidized by Bound Redox-active Iron

Honda, K., Smith, M. A., Zhu, X., Baus, D., Merrick, W. C., Tartakoff, A. M., Hattier, T., Harris, P. L., Siedlak, S. L., Fujioka, H., et al. (2005) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 280

Insulin-resistant brain state: The culprit in sporadic Alzheimer's disease?

Correia, S. C., Santos, R. X., Perry, G., Zhu, X., Moreira, P. I., & Smith, M. A. (2011) · Ageing Research Reviews

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 212

Iron: The Redox-active Center of Oxidative Stress in Alzheimer Disease

Castellani, R. J., Moreira, P. I., Liu, G., Dobson, J., Perry, G., Smith, M. A., & Zhu, X. (2007) · Neurochemical Research

Alzheimer's disease research and treatmentsIron Metabolism and Disorders

Cited by 180

RNA oxidation in Alzheimer disease and related neurodegenerative disorders

Nunomura, A., Hofer, T., Moreira, P. I., Castellani, R. J., Smith, M. A., & Perry, G. (2009) · Acta Neuropathologica

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 148

Alzheimer’s disease and type 2 diabetes-related alterations in brain mitochondria, autophagy and synaptic markers

Carvalho, C., Santos, M. S., Oliveira, C. R., & Moreira, P. I. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 145

Increased Vulnerability of Brain Mitochondria in Diabetic (Goto-Kakizaki) Rats With Aging and Amyloid-β Exposure

Moreira, P. I., Santos, M. S., Moreno, A. M., Seiça, R., & Oliveira, C. R. (2003) · Diabetes

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 117

Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia

Carvalho, C., Correia, S. C., Santos, R. X., Cardoso, S., Moreira, P. I., Clark, T. A., Zhu, X., Smith, M. A., & Perry, G. (2009) · Journal of Bioenergetics and Biomembranes

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 72

Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies

Pinho, T. S., Correia, S. C., Perry, G., Ambrósio, A. F., & Moreira, P. I. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Alzheimer's disease research and treatmentsGlycosylation and Glycoproteins Research

Cited by 70

A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss

Chiquita, S., Ribeiro, M., Castelhano, J., Oliveira, F., Sereno, J., Batista, M., Abrunhosa, A., Rodrigues-Neves, A. C., Carecho, R., Baptista, F., et al. (2019) · Human Molecular Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 63

Insulin therapy modulates mitochondrial dynamics and biogenesis, autophagy and tau protein phosphorylation in the brain of type 1 diabetic rats

Santos, R. X., Correia, S. C., Alves, M. G., Oliveira, P. F., Cardoso, S., Carvalho, C., Duarte, A. I., Santos, M. S., & Moreira, P. I. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 61

Antidiabetic drugs for Alzheimer's and Parkinson's diseases: Repurposing insulin, metformin, and thiazolidinediones

Cardoso, S., & Moreira, P. I. (2020) · International Review of Neurobiology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 58

Nuclear and mitochondrial DNA oxidation in Alzheimer's disease

Santos, R. X., Correia, S. C., Zhu, X., Lee, H.-G., Petersen, R. B., Nunomura, A., Smith, M. A., Perry, G., & Moreira, P. I. (2012) · Free Radical Research

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 57

Autophagy in Alzheimer’s disease

Moreira, P. I., Santos, R. X., Zhu, X., Lee, H.-G., Smith, M. A., Casadesus, G., & Perry, G. (2010) · Expert Review of Neurotherapeutics

Autophagy in Disease and TherapyAlzheimer's disease research and treatments

Cited by 55