Weyand, Cornelia M.

Immunometabolism in the development of rheumatoid arthritis

Weyand, C. M., & Goronzy, J. J. (2020) · Immunological Reviews

Rheumatoid Arthritis Research and TherapiesT-cell and B-cell Immunology

Cited by 193

Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4+CD28− T cells from rheumatoid arthritis patients

Schirmer, M., Vallejo, A. N., Weyand, C. M., & Goronzy, J. J. (1998) · The Journal of Immunology

T-cell and B-cell ImmunologyCell death mechanisms and regulation

Cited by 191

Homeostatic control of T-cell generation in neonates

Schönland, S. O., Zimmer, J. K., Lopez-Benitez, C. M., Widmann, T., Ramin, K. D., Goronzy, J. J., & Weyand, C. M. (2003) · Blood

T-cell and B-cell ImmunologyHematopoietic Stem Cell Transplantation

Cited by 178

Telomerase insufficiency in rheumatoid arthritis

Fujii, H., Shao, L., Colmegna, I., Goronzy, J. J., & Weyand, C. M. (2009) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceRheumatoid Arthritis Research and Therapies

Cited by 172

Clonality and longevity of CD4+CD28null T cells are associated with defects in apoptotic pathways

Vallejo, A. N., Schirmer, M., Weyand, C. M., & Goronzy, J. J. (2000) · The Journal of Immunology

T-cell and B-cell ImmunologyCell death mechanisms and regulation

Cited by 169

T-cell aging in rheumatoid arthritis

Weyand, C. M., Yang, Z., & Goronzy, J. J. (2014) · Current Opinion in Rheumatology

Telomeres, Telomerase, and SenescenceT-cell and B-cell Immunology

Cited by 164

Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis.

Shao, L., Fujii, H., Colmegna, I., Oishi, H., Goronzy, J. J., & Weyand, C. M. (2009) · Journal of Experimental Medicine

DNA Repair MechanismsRheumatoid Arthritis Research and Therapies

Cited by 159

NADPH oxidase deficiency underlies dysfunction of aged CD8+ Tregs

Wen, Z., Shimojima, Y., Shirai, T., Li, Y., Ju, J., Yang, Z., Tian, L., Goronzy, J. J., & Weyand, C. M. (2016) · Journal of Clinical Investigation

T-cell and B-cell ImmunologyNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 146

Mitochondrial aspartate regulates TNF biogenesis and autoimmune tissue inflammation

Wu, B., Zhao, T. V., Jin, K., Hu, Z., Abdel, M. P., Warrington, K. J., Goronzy, J. J., & Weyand, C. M. (2021) · Nature Immunology

Rheumatoid Arthritis Research and TherapiesMitochondrial Function and Pathology

Cited by 141

Expression of CD39 on activated T cells impairs their survival in older individuals

Fang, F., Yu, M., Cavanagh, M. M., Hutter Saunders, J., Qi, Q., Ye, Z., Le Saux, S., Sultan, W., Turgano, E., Dekker, C. L., et al. (2016) · Cell Reports

T-cell and B-cell ImmunologyAdenosine and Purinergic Signaling

Cited by 138

Signaling pathways in aged T cells – A reflection of T cell differentiation, cell senescence and host environment

Goronzy, J. J., Li, G., Yu, M., & Weyand, C. M. (2012) · Seminars in Immunology

T-cell and B-cell ImmunologyGenetics, Aging, and Longevity in Model Organisms

Cited by 134

De novo expression of killer immunoglobulin-like receptors and signaling proteins regulates the cytotoxic function of CD4 T cells in acute coronary syndromes.

Nakajima, T., Goek, O., Zhang, X., Kopecky, S. L., Frye, R. L., Goronzy, J. J., & Weyand, C. M. (2003) · Circulation Research

Immune Cell Function and InteractionAtherosclerosis and Cardiovascular Diseases

Cited by 127

Rejuvenating the immune system in rheumatoid arthritis.

Weyand, C. M., Fujii, H., Shao, L., & Goronzy, J. J. (2009) · Nature Reviews Rheumatology

Telomeres, Telomerase, and SenescenceRheumatoid Arthritis Research and Therapies

Cited by 112

Telomeres and immunological diseases of aging.

Andrews, N. P., Fujii, H., Goronzy, J. J., & Weyand, C. M. (2010) · Gerontology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 108

Defective proliferative capacity and accelerated telomeric loss of hematopoietic progenitor cells in rheumatoid arthritis.

Colmegna, I., Diaz‐Borjon, A., Fujii, H., Schaefer, L., Goronzy, J. J., & Weyand, C. M. (2008) · Arthritis & Rheumatism

Rheumatoid Arthritis Research and TherapiesHematopoietic Stem Cell Transplantation

Cited by 108

Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age

Yu, M., Li, G., Lee, W.-W., Yuan, M., Cui, D., Weyand, C. M., & Goronzy, J. J. (2012) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyProtein Tyrosine Phosphatases

Cited by 102

Chronic inflammation and aging: DNA damage tips the balance

Cavanagh, M. M., Weyand, C. M., & Goronzy, J. J. (2012) · Current Opinion in Immunology

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 99

DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis.

Shao, L., Goronzy, J. J., & Weyand, C. M. (2010) · EMBO Molecular Medicine

DNA Repair MechanismsRheumatoid Arthritis Research and Therapies

Cited by 69

Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin-like receptors

Henel, G., Singh, K., Cui, D., Pryshchep, S., Lee, W.-W., Weyand, C. M., & Goronzy, J. J. (2006) · Blood

Immune Cell Function and InteractionT-cell and B-cell Immunology

Cited by 61

Epigenetics of T cell aging

Goronzy, J. J., Hu, B., Kim, C., Jadhav, R. R., & Weyand, C. M. (2018) · Journal of Leukocyte Biology

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 60

Tissue trafficking patterns of effector memory CD4 T cells in rheumatoid arthritis.

Zhang, X., Nakajima, T., Goronzy, J. J., & Weyand, C. M. (2005) · Arthritis & Rheumatism

Rheumatoid Arthritis Research and TherapiesT-cell and B-cell Immunology

Cited by 56

T-Cell Aging-Associated Phenotypes in Autoimmune Disease

Zhao, T. V., Sato, Y., Goronzy, J. J., & Weyand, C. M. (2022) · Frontiers in Aging

T-cell and B-cell ImmunologyGenetics, Aging, and Longevity in Model Organisms

Cited by 50

Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages

Lamar, D. L., Weyand, C. M., & Goronzy, J. J. (2010) · Blood

Immune Cell Function and InteractionT-cell and B-cell Immunology

Cited by 45

Haematopoietic stem and progenitor cells in rheumatoid arthritis.

Colmegna, I., & Weyand, C. M. (2011) · Rheumatology

Hematopoietic Stem Cell TransplantationRheumatoid Arthritis Research and Therapies

Cited by 37