Dowsett, Mitch

Trastuzumab after Adjuvant Chemotherapy in HER2-Positive Breast Cancer

Piccart-Gebhart, M. J., Procter, M., Leyland-Jones, B., Goldhirsch, A., Untch, M., Smith, I., Gianni, L., Baselga, J., Bell, R., Jackisch, C., et al. (2005) · New England Journal of Medicine

HER2/EGFR in Cancer ResearchBreast Cancer Treatment Studies

Cited by 5,084

Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial

Cuzick, J., Sestak, I., Baum, M., Buzdar, A., Howell, A., Dowsett, M., & Forbes, J. F. (2010) · The Lancet Oncology

Breast Cancer Treatment StudiesEstrogen and related hormone effects

Cited by 1,674

Phase I Clinical Trial of a Selective Inhibitor of CYP17, Abiraterone Acetate, Confirms That Castration-Resistant Prostate Cancer Commonly Remains Hormone Driven

Attard, G., Reid, A. H. M., Yap, T. A., Raynaud, F., Dowsett, M., Settatree, S., Barrett, M., Parker, C., Martins, V., Folkerd, E., et al. (2008) · Journal of Clinical Oncology

Prostate Cancer Treatment and ResearchProstate Cancer Diagnosis and Treatment

Cited by 903

Endogenous Testosterone and Mortality Due to All Causes, Cardiovascular Disease, and Cancer in Men: European Prospective Investigation Into Cancer in Norfolk (EPIC-Norfolk) Prospective Population Study

Khaw, K.-T., Dowsett, M., Folkerd, E., Bingham, S., Wareham, N., Luben, R., Welch, A., & Day, N. (2007) · Circulation

Hormonal and reproductive studiesSperm and Testicular Function

Cited by 743

Plasma ESR1 Mutations and the Treatment of Estrogen Receptor–Positive Advanced Breast Cancer

Fribbens, C., O’Leary, B., Kilburn, L., Hrebien, S., Garcia-Murillas, I., Beaney, M., Cristofanilli, M., Andre, F., Loi, S., Loibl, S., et al. (2016) · Journal of Clinical Oncology

Advanced Breast Cancer TherapiesBreast Cancer Treatment Studies

Cited by 722

Mechanisms of tamoxifen resistance

Ring, A., & Dowsett, M. (2004) · Endocrine-Related Cancer

Estrogen and related hormone effectsBreast Cancer Treatment Studies

Cited by 651

Selective Inhibition of CYP17 With Abiraterone Acetate Is Highly Active in the Treatment of Castration-Resistant Prostate Cancer

Attard, G., Reid, A. H. M., A'Hern, R., Parker, C., Oommen, N. B., Folkerd, E., Messiou, C., Molife, L. R., Maier, G., Thompson, E., et al. (2009) · Journal of Clinical Oncology

Prostate Cancer Treatment and ResearchProstate Cancer Diagnosis and Treatment

Cited by 605

Influence of Letrozole and Anastrozole on Total Body Aromatization and Plasma Estrogen Levels in Postmenopausal Breast Cancer Patients Evaluated in a Randomized, Cross-Over Study

Geisler, J., Haynes, B., Anker, G., Dowsett, M., & Lønning, P. E. (2002) · Journal of Clinical Oncology

Estrogen and related hormone effectsBreast Cancer Treatment Studies

Cited by 604

Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial

Cuzick, J., Sestak, I., Forbes, J. F., Dowsett, M., Knox, J., Cawthorn, S., Saunders, C., Roche, N., Mansel, R. E., von Minckwitz, G., et al. (2014) · The Lancet

Breast Cancer Treatment StudiesCancer Risks and Factors

Cited by 590

ERα-Dependent E2F Transcription Can Mediate Resistance to Estrogen Deprivation in Human Breast Cancer

Miller, T. W., Balko, J. M., Fox, E. M., Ghazoui, Z., Dunbier, A., Anderson, H., Dowsett, M., Jiang, A., Smith, R. A., Maira, S.-M., et al. (2011) · Cancer Discovery

Estrogen and related hormone effectsAdvanced Breast Cancer Therapies

Cited by 346

Fulvestrant plus anastrozole or placebo versus exemestane alone after progression on non-steroidal aromatase inhibitors in postmenopausal patients with hormone-receptor-positive locally advanced or metastatic breast cancer (SoFEA): a composite, multicentre, phase 3 randomised trial

Johnston, S. R., Kilburn, L. S., Ellis, P., Dodwell, D., Cameron, D., Hayward, L., Im, Y.-H., Braybrooke, J. P., Brunt, A. M., Cheung, K.-L., et al. (2013) · The Lancet Oncology

Advanced Breast Cancer TherapiesBreast Cancer Treatment Studies

Cited by 274

Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer risk in European prospective investigation of cancer and nutrition-norfolk

Grace, P. B., Taylor, J. I., Low, Y.-L., Luben, R. N., Mulligan, A. A., Botting, N. P., Dowsett, M., Welch, A. A., Khaw, K.-T., Wareham, N. J., et al. (2004) · Cancer Epidemiology, Biomarkers & Prevention

Phytoestrogen effects and researchPhytochemicals and Antioxidant Activities

Cited by 264

Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance

Balko, J. M., Cook, R. S., Vaught, D. B., Kuba, M. G., Miller, T. W., Bhola, N. E., Sanders, M. E., Granja-Ingram, N. M., Smith, J. J., Meszoely, I. M., et al. (2012) · Nature Medicine

Breast Cancer Treatment StudiesProtein Tyrosine Phosphatases

Cited by 262

Influence of Sex Hormones on Cancer Progression

Folkerd, E. J., & Dowsett, M. (2010) · Journal of Clinical Oncology

Estrogen and related hormone effectsProstate Cancer Treatment and Research

Cited by 229

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170

EMBRACE, Dunning, A. M., Collaborators, G. S., HEBON, kConFab Investigators, Michailidou, K., Kuchenbaecker, K. B., Thompson, D., French, J. D., Beesley, J., et al. (2016) · Nature Genetics

Genetic Associations and EpidemiologyEstrogen and related hormone effects

Cited by 161

Red-clover-derived isoflavones and mammographic breast density: a double-blind, randomized, placebo-controlled trial [ISRCTN42940165

Atkinson, C., Warren, R. M., Sala, E., Dowsett, M., Dunning, A. M., Healey, C. S., Runswick, S., Day, N. E., & Bingham, S. A. (2004) · Breast Cancer Research

Phytoestrogen effects and researchDigital Radiography and Breast Imaging

Cited by 151

Physical activity and inactivity in relation to sex hormone, prolactin, and insulin-like growth factor concentrations in premenopausal women: Exercise and premenopausal hormones

Tworoger, S. S., Missmer, S. A., Eliassen, A. H., Barbieri, R. L., Dowsett, M., & Hankinson, S. E. (2007) · Cancer Causes & Control

Cancer Risks and FactorsPhysical Activity and Health

Cited by 78

Identification of Common Variants in the SHBG Gene Affecting Sex Hormone-Binding Globulin Levels and Breast Cancer Risk in Postmenopausal Women

Thompson, D. J., Healey, C. S., Baynes, C., Kalmyrzaev, B., Ahmed, S., Dowsett, M., Folkerd, E., Luben, R. N., Cox, D., Ballinger, D., et al. (2008) · Cancer Epidemiology, Biomarkers & Prevention

Genetic Associations and EpidemiologyEstrogen and related hormone effects

Cited by 61

Biochemistry and pharmacokinetics of potent non-steroidal cytochrome P45017α inhibitors

Barrie, S. E., Haynes, B. P., Potter, G. A., Chan, F. C. Y., Goddard, P. M., Dowsett, M., & Jarman, M. (1997) · The Journal of Steroid Biochemistry and Molecular Biology

Adrenal Hormones and DisordersPharmacogenetics and Drug Metabolism

Cited by 37

Validation and use of centrifugal ultrafiltration-dialysis in the measurement of percent free oestradiol in serum

Dowsett, M., Mansfield, M. D., Griggs, D. J., & Jeffcoate, S. L. (1984) · Journal of Steroid Biochemistry

Estrogen and related hormone effectsProtein Interaction Studies and Fluorescence Analysis

Cited by 28

Anastrozole – A New Generation in Aromatase Inhibition: Clinical Pharmacology

Dowsett, M., & Lonning, P. E. (2009) · Oncology

Estrogen and related hormone effectsBreast Cancer Treatment Studies

Cited by 21

DOSAGE‐RELATED EFFECTS OF DANAZOL ON SEX HORMONE BINDING GLOBULIN AND FREE AND TOTAL ANDROGEN LEVELS

FORBES, K. L., DOWSETT, M., ROSE, G. L., MUDGE, J. E., & JEFFCOATE, S. L. (1986) · Clinical Endocrinology

Hormonal and reproductive studiesAdrenal Hormones and Disorders

Cited by 16

Reply to M. Rosman et al

Dowsett, M., Pineda, S., & Cuzick, J. (2010) · Journal of Clinical Oncology

Breast Cancer Treatment StudiesHER2/EGFR in Cancer Research

Cited by 1