Shapiro, Lawrence

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

Wang, P., Nair, M. S., Liu, L., Iketani, S., Luo, Y., Guo, Y., Wang, M., Yu, J., Zhang, B., Kwong, P. D., et al. (2021) · Nature

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 2,328

Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7

Wang, P., Nair, M. S., Liu, L., Iketani, S., Luo, Y., Guo, Y., Wang, M., Yu, J., Zhang, B., Kwong, P. D., et al. (2021) · Nature

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 2,312

Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike

Liu, L., Wang, P., Nair, M. S., Yu, J., Rapp, M., Wang, Q., Luo, Y., Chan, J. F.-W., Sahi, V., Figueroa, A., et al. (2020) · Nature

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 1,349

Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization

Wang, P., Casner, R. G., Nair, M. S., Wang, M., Yu, J., Cerutti, G., Liu, L., Kwong, P. D., Huang, Y., Shapiro, L., et al. (2021) · Cell Host & Microbe

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 636

Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite

Cerutti, G., Guo, Y., Zhou, T., Gorman, J., Lee, M., Rapp, M., Reddem, E. R., Yu, J., Bahna, F., Bimela, J., et al. (2021) · Cell Host & Microbe

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 519

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

Joyce, M. G., Wheatley, A. K., Thomas, P. V., Chuang, G.-Y., Soto, C., Bailer, R. T., Druz, A., Georgiev, I. S., Gillespie, R. A., Kanekiyo, M., et al. (2016) · Cell

Influenza Virus Research Studiesvaccines and immunoinformatics approaches

Cited by 333

Structure of the STRA6 receptor for retinol uptake

Chen, Y., Clarke, O. B., Kim, J., Stowe, S., Kim, Y.-K., Assur, Z., Cavalier, M., Godoy-Ruiz, R., von Alpen, D. C., Manzini, C., et al. (2016) · Science

Retinoids in leukemia and cellular processesReceptor Mechanisms and Signaling

Cited by 148

P-cadherin is a p63 target gene with a crucial role in the developing human limb bud and hair follicle

Shimomura, Y., Wajid, M., Shapiro, L., & Christiano, A. M. (2008) · Development

Hair Growth and Disordersdental development and anomalies

Cited by 122

Visualization of clustered protocadherin neuronal self-recognition complexes

Brasch, J., Goodman, K. M., Noble, A. J., Rapp, M., Mannepalli, S., Bahna, F., Dandey, V. P., Bepler, T., Berger, B., Maniatis, T., et al. (2019) · Nature

Axon Guidance and Neuronal SignalingNeuroscience and Neuropharmacology Research

Cited by 99

Free energy perturbation calculation of relative binding free energy between broadly neutralizing antibodies and the gp120 glycoprotein of HIV-1

Clark, A. J., Gindin, T., Zhang, B., Wang, L., Abel, R., Murret, C. S., Xu, F., Bao, A., Lu, N. J., Zhou, T., et al. (2017) · Journal of Molecular Biology

Protein Structure and DynamicsComputational Drug Discovery Methods

Cited by 96

Motor neuron position and topographic order imposed by β- And γ-catenin activities

Demireva, E. Y., Shapiro, L. S., Jessell, T. M., & Zampieri, N. (2011) · Cell

Developmental Biology and Gene RegulationAxon Guidance and Neuronal Signaling

Cited by 85

DIP/Dpr interactions and the evolutionary design of specificity in protein families

Sergeeva, A. P., Katsamba, P. S., Cosmanescu, F., Brewer, J. J., Ahlsen, G., Mannepalli, S., Shapiro, L., & Honig, B. (2020) · Nature Communications

Protein Structure and DynamicsAxon Guidance and Neuronal Signaling

Cited by 38

Free energy perturbation calculations of mutation effects on SARS-CoV-2 RBD::ACE2 binding affinity

Sergeeva, A. P., Katsamba, P. S., Liao, J., Sampson, J. M., Bahna, F., Mannepalli, S., Morano, N. C., Shapiro, L., Friesner, R. A., & Honig, B. (2023) · Journal of Molecular Biology

SARS-CoV-2 and COVID-19 ResearchProtein Structure and Dynamics

Cited by 27

Robust prediction of relative binding energies for protein-protein complex mutations using free energy perturbation calculations

Sampson, J. M., Cannon, D. A., Duan, J., Epstein, J. C. K., Sergeeva, A. P., Katsamba, P. S., Mannepalli, S. M., Bahna, F. A., Adihou, H., Guéret, S. M., et al. (2024) · Journal of Molecular Biology

Protein Structure and DynamicsComputational Drug Discovery Methods

Cited by 24

Optimizing a Human Monoclonal Antibody for Better Neutralization of SARS-CoV-2

Wang, Q., Guo, Y., Casner, R. G., Yu, J., Nair, M. S., Ho, J., Reddem, E. R., Mellis, I. A., Wu, M., Tzang, C. C., et al. (2024) · Nature Communications

SARS-CoV-2 and COVID-19 ResearchMonoclonal and Polyclonal Antibodies Research

Cited by 15

Optimizing a human monoclonal antibody for better neutralization of SARS-CoV-2

Wang, Q., Guo, Y., Casner, R. G., Yu, J., Nair, M. S., Ho, J., Reddem, E. R., Mellis, I. A., Wu, M., Tzang, C.-C., et al. (2025) · Nature Communications

SARS-CoV-2 and COVID-19 ResearchMonoclonal and Polyclonal Antibodies Research

Cited by 15

Deep Mining of the Human Antibody Repertoire Identifies Frequent and Genetically Diverse CDRH3 Topologies Targetable by Vaccination

Habib, R., Solieva, S. O., Lin, Z. J., Ghosh, S., Bayruns, K., Singh, M., Agostino, C. J., Tursi, N. J., Sowers, K. J., Huang, J., et al. (2024) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentMonoclonal and Polyclonal Antibodies Research

Cited by 8

Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation

Quintana-Feliciano, R., Kottur, J., Ni, M., Ghosh, R., Salas-Estrada, L., Ahlsen, G., Rechkoblit, O., Shapiro, L., Filizola, M., Fang, G., et al. (2024) · Nature Communications

Epigenetics and DNA MethylationEnzyme Structure and Function

Cited by 3