Radtke, Freddy

Self-Renewal and Cancer of the Gut: Two Sides of a Coin

Radtke, F., & Clevers, H. (2005) · Science

Wnt/β-catenin signaling in development and cancerCancer Cells and Metastasis

Cited by 690

Notch regulation of lymphocyte development and function

Radtke, F., Wilson, A., Mancini, S. J. C., & MacDonald, H. R. (2004) · Nature Immunology

Developmental Biology and Gene RegulationT-cell and B-cell Immunology

Cited by 539

Signalling strength determines proapoptotic functions of STING

Gulen, M. F., Koch, U., Haag, S. M., Schuler, F., Apetoh, L., Villunger, A., Radtke, F., & Ablasser, A. (2017) · Nature Communications

interferon and immune responsesImmune Response and Inflammation

Cited by 505

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment

Koch, U., Fiorini, E., Benedito, R., Besseyrias, V., Schuster-Gossler, K., Pierres, M., Manley, N. R., Duarte, A., MacDonald, H. R., & Radtke, F. (2008) · The Journal of Experimental Medicine

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 464

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

Amsen, D., Antov, A., Jankovic, D., Sher, A., Radtke, F., Souabni, A., Busslinger, M., McCright, B., Gridley, T., & Flavell, R. A. (2007) · Immunity

T-cell and B-cell ImmunologyDevelopmental Biology and Gene Regulation

Cited by 396

Canonical Notch Signaling Is Dispensable for the Maintenance of Adult Hematopoietic Stem Cells

Maillard, I., Koch, U., Dumortier, A., Shestova, O., Xu, L., Sai, H., Pross, S. E., Aster, J. C., Bhandoola, A., Radtke, F., et al. (2008) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationDevelopmental Biology and Gene Regulation

Cited by 317

Notch1 is required for maintenance of the reservoir of adult hippocampal stem cells

Ables, J. L., DeCarolis, N. A., Johnson, M. A., Rivera, P. D., Gao, Z., Cooper, D. C., Radtke, F., Hsieh, J., & Eisch, A. J. (2010) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 292

Stem cells living with a Notch

Koch, U., Lehal, R., & Radtke, F. (2013) · Development

Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms

Cited by 283

Critical role of endothelial Notch1 signaling in postnatal angiogenesis

Takeshita, K., Satoh, M., Ii, M., Silver, M., Limbourg, F. P., Mukai, Y., Rikitake, Y., Radtke, F., Gridley, T., Losordo, D. W., et al. (2007) · Circulation Research

Angiogenesis and VEGF in CancerDevelopmental Biology and Gene Regulation

Cited by 232

Notch1 control of oligodendrocyte differentiation in the spinal cord

Genoud, S., Lappe-Siefke, C., Goebbels, S., Radtke, F., Aguet, M., Scherer, S. S., Suter, U., Nave, K.-A., & Mantei, N. (2002) · The Journal of Cell Biology

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 211

Notch Signaling Is Required for Exocrine Regeneration After Acute Pancreatitis

Siveke, J. T., Lubeseder–Martellato, C., Lee, M., Mazur, P. K., Nakhai, H., Radtke, F., & Schmid, R. M. (2008) · Gastroenterology

Pancreatitis Pathology and TreatmentPancreatic function and diabetes

Cited by 162

Notch2 signaling maintains NSC quiescence in the murine ventricular-subventricular zone

Engler, A., Rolando, C., Giachino, C., Saotome, I., Erni, A., Brien, C., Zhang, R., Zimber-Strobl, U., Radtke, F., Artavanis-Tsakonas, S., et al. (2018) · Cell Reports

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 125