Darley-Usmar, Victor M.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide: Implications for neurodegenerative diseases

Cleeter, M. W. J., Cooper, J. M., Darley-Usmar, V. M., Moncada, S., & Schapira, A. H. V. (1994) · FEBS Letters

Mitochondrial Function and PathologyNitric Oxide and Endothelin Effects

Cited by 1,241

Deoxymyoglobin Is a Nitrite Reductase That Generates Nitric Oxide and Regulates Mitochondrial Respiration

Shiva, S., Huang, Z., Grubina, R., Sun, J., Ringwood, L. A., MacArthur, P. H., Xu, X., Murphy, E., Darley-Usmar, V. M., & Gladwin, M. T. (2007) · Circulation Research

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

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Biological aspects of reactive nitrogen species

Patel, R. P., McAndrew, J., Sellak, H., White, C. R., Jo, H., Freeman, B. A., & Darley-Usmar, V. M. (1999) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 498

Assessing bioenergetic function in response to oxidative stress by metabolic profiling

Dranka, B. P., Benavides, G. A., Diers, A. R., Giordano, S., Zelickson, B. R., Reily, C., Zou, L., Chatham, J. C., Hill, B. G., Zhang, J., et al. (2011) · Free Radical Biology and Medicine

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 436

Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits.

White, C. R., Darley-Usmar, V, Berrington, W. R., McAdams, M., Gore, J. Z., Thompson, J. A., Parks, D. A., Tarpey, M. M., & Freeman, B. A. (1996) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsGout, Hyperuricemia, Uric Acid

Cited by 367

Concentration-dependent Effects of Nitric Oxide on Mitochondrial Permeability Transition and Cytochrome cRelease

Brookes, P. S., Salinas, E. P., Darley-Usmar, K., Eiserich, J. P., Freeman, B. A., Darley-Usmar, V. M., & Anderson, P. G. (2000) · Journal of Biological Chemistry

Mitochondrial Function and PathologyCell death mechanisms and regulation

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What Part of NO Don't You Understand? Some Answers to the Cardinal Questions in Nitric Oxide Biology

Hill, B. G., Dranka, B. P., Bailey, S. M., Lancaster, J. R., & Darley-Usmar, V. M. (2010) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

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Mitochondria: regulators of signal transduction by reactive oxygen and nitrogen species

Brookes, P. S., Levonen, A.-L., Shiva, S., Sarti, P., & Darley-Usmar, V. M. (2002) · Free Radical Biology and Medicine

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 298

Nitration of Unsaturated Fatty Acids by Nitric Oxide-Derived Reactive Nitrogen Species Peroxynitrite, Nitrous Acid, Nitrogen Dioxide, and Nitronium Ion

O'Donnell, V. B., Eiserich, J. P., Chumley, P. H., Jablonsky, M. J., Krishna, N. R., Kirk, M., Barnes, S., Darley-Usmar, V. M., & Freeman, B. A. (1999) · Chemical Research in Toxicology

Antioxidant Activity and Oxidative StressNitric Oxide and Endothelin Effects

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High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo

Mantena, S. K., Vaughn, D. P., Andringa, K. K., Eccleston, H. B., King, A. L., Abrams, G. A., Doeller, J. E., Kraus, D. W., Darley-Usmar, V. M., & Bailey, S. M. (2009) · Biochemical Journal

Liver Disease Diagnosis and TreatmentMitochondrial Function and Pathology

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Mitochondrially targeted compounds and their impact on cellular bioenergetics

Reily, C., Mitchell, T., Chacko, B. K., Benavides, G. A., Murphy, M. P., & Darley-Usmar, V. M. (2013) · Redox Biology

Mitochondrial Function and PathologyRedox biology and oxidative stress

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Prevention of diabetic nephropathy in Ins2+/−AkitaJ mice by the mitochondria-targeted therapy MitoQ

Chacko, B. K., Reily, C., Srivastava, A., Johnson, M. S., Ye, Y., Ulasova, E., Agarwal, A., Zinn, K. R., Murphy, M. P., Kalyanaraman, B., et al. (2010) · Biochemical Journal

Chronic Kidney Disease and DiabetesMitochondrial Function and Pathology

Cited by 204

Nanotransducers in cellular redox signaling: modification of thiols by reactive oxygen and nitrogen species

Cooper, C. E., Patel, R. P., Brookes, P. S., & Darley-Usmar, V. M. (2002) · Trends in Biochemical Sciences

Redox biology and oxidative stressSulfur Compounds in Biology

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Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice

Pak, H. H., Haws, S. A., Green, C. L., Koller, M., Lavarias, M. T., Richardson, N. E., Yang, S. E., Dumas, S. N., Sonsalla, M., Bray, L., et al. (2021) · Nature Metabolism

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

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Modification of the mitochondrial proteome in response to the stress of ethanol-dependent hepatotoxicity

Venkatraman, A., Landar, A., Davis, A. J., Chamlee, L., Sanderson, T., Kim, H., Page, G., Pompilius, M., Ballinger, S., Darley-Usmar, V., et al. (2004) · Journal of Biological Chemistry

Mitochondrial Function and PathologyAlcohol Consumption and Health Effects

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Hypothesis: the mitochondrial NO(*) signaling pathway, and the transduction of nitrosative to oxidative cell signals: an alternative function for cytochrome c oxidase

Brookes, P., & Darley-Usmar, V. M. (2002) · Free Radical Biology and Medicine

Mitochondrial Function and PathologyRedox biology and oxidative stress

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Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis

Chacko, B. K., Srivastava, A., Johnson, M. S., Benavides, G. A., Chang, M. J., Ye, Y., Jhala, N., Murphy, M. P., Kalyanaraman, B., & Darley-Usmar, V. M. (2011) · Hepatology

Alcohol Consumption and Health EffectsCoenzyme Q10 studies and effects

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The role of iNOS in alcohol-dependent hepatotoxicity and mitochondrial dysfunction in mice

Venkatraman, A., Shiva, S., Wigley, A., Ulasova, E., Chhieng, D., Bailey, S. M., & Darley-Usmar, V. M. (2004) · Hepatology

Alcohol Consumption and Health EffectsMitochondrial Function and Pathology

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Nitroxia: The pathological consequence of dysfunction in the nitric oxide–cytochrome c oxidase signaling pathway

Shiva, S., Oh, J.-Y., Landar, A. L., Ulasova, E., Venkatraman, A., Bailey, S. M., & Darley-Usmar, V. M. (2005) · Free Radical Biology and Medicine

Mitochondrial Function and PathologyNitric Oxide and Endothelin Effects

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Oxidative modification of hepatic mitochondria protein thiols: effect of chronic alcohol consumption

Venkatraman, A., Landar, A., Davis, A. J., Ulasova, E., Page, G., Murphy, M. P., Darley-Usmar, V., & Bailey, S. M. (2004) · American Journal of Physiology-Gastrointestinal and Liver Physiology

Redox biology and oxidative stressAlcohol Consumption and Health Effects

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Mechanisms of the interaction of nitroxyl with mitochondria

SHIVA, S., CRAWFORD, J. H., RAMACHANDRAN, A., CEASER, E. K., HILLSON, T., BROOKES, P. S., PATEL, R. P., & DARLEY-USMAR, V. M. (2004) · Biochemical Journal

Mitochondrial Function and PathologyRedox biology and oxidative stress

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Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: implications for mitochondrial therapeutics

Mitchell, T., Chacko, B., Ballinger, S. W., Bailey, S. M., Zhang, J., & Darley-Usmar, V. (2013) · Biochemical Society Transactions

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

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Metabolic alterations mediated by STAT3 promotes drug persistence in CML

Patel, S. B., Nemkov, T., Stefanoni, D., Benavides, G. A., Bassal, M. A., Crown, B. L., Matkins, V. R., Camacho, V., Kuznetsova, V., Hoang, A. T., et al. (2021) · Leukemia

Chronic Myeloid Leukemia TreatmentsAcute Myeloid Leukemia Research

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