Groudine, Mark

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

Lieberman-Aiden, E., van Berkum, N. L., Williams, L., Imakaev, M., Ragoczy, T., Telling, A., Amit, I., Lajoie, B. R., Sabo, P. J., Dorschner, M. O., et al. (2009) · Science

Genomics and Chromatin DynamicsChromosomal and Genetic Variations

Cited by 8,898

Expanded encyclopaedias of DNA elements in the human and mouse genomes

The ENCODE Project Consortium, Abascal, F., Acosta, R., Addleman, N. J., Adrian, J., Afzal, V., Ai, R., Aken, B., Akiyama, J. A., Jammal, O. A., et al. (2020) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 2,378

Chromosomal Subunits in Active Genes Have an Altered Conformation: Globin genes are digested by deoxyribonuclease I in red blood cell nuclei but not in fibroblast nuclei.

Weintraub, H., & Groudine, M. (1976) · Science

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 1,809

A comparative encyclopedia of DNA elements in the mouse genome

Yue, F., Cheng, Y., Breschi, A., Vierstra, J., Wu, W., Ryba, T., Sandstrom, R., Ma, Z., Davis, C., Pope, B. D., et al. (2014) · Nature

Genomics and Chromatin DynamicsChromosomal and Genetic Variations

Cited by 1,781

Functional and Mechanistic Diversity of Distal Transcription Enhancers

Bulger, M., & Groudine, M. (2011) · Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 803

Proximity among Distant Regulatory Elements at the β-Globin Locus Requires GATA-1 and FOG-1

Vakoc, C. R., Letting, D. L., Gheldof, N., Sawado, T., Bender, M. A., Groudine, M., Weiss, M. J., Dekker, J., & Blobel, G. A. (2005) · Molecular Cell

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 490

An encyclopedia of mouse DNA elements (Mouse ENCODE)

Mouse ENCODE Consortium, Stamatoyannopoulos, J. A., Snyder, M., Hardison, R., Ren, B., Gingeras, T., Gilbert, D. M., Groudine, M., Bender, M., Kaul, R., et al. (2012) · Genome Biology

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 446

Developmental and species-divergent globin switching are driven by BCL11A

Sankaran, V. G., Xu, J., Ragoczy, T., Ippolito, G. C., Walkley, C. R., Maika, S. D., Fujiwara, Y., Ito, M., Groudine, M., Bender, M. A., et al. (2009) · Nature

Hemoglobinopathies and Related DisordersHemoglobin structure and function

Cited by 379

Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network

Sun, J., Brand, M., Zenke, Y., Tashiro, S., Groudine, M., & Igarashi, K. (2004) · Proceedings of the National Academy of Sciences

Genomics, phytochemicals, and oxidative stressHeme Oxygenase-1 and Carbon Monoxide

Cited by 364

β-globin Gene Switching and DNase I Sensitivity of the Endogenous β-globin Locus in Mice Do Not Require the Locus Control Region

Bender, M. A., Bulger, M., Close, J., & Groudine, M. (2000) · Molecular Cell

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 224

Conservation of trans-acting circuitry during mammalian regulatory evolution

Stergachis, A. B., Neph, S., Sandstrom, R., Haugen, E., Reynolds, A. P., Zhang, M., Byron, R., Canfield, T., Stelhing-Sun, S., Lee, K., et al. (2014) · Nature

Genomics and Chromatin DynamicsChromosomal and Genetic Variations

Cited by 212

Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3′ enhancer

Muto, A., Hoshino, H., Madisen, L., Yanai, N., Obinata, M., Karasuyama, H., Hayashi, N., Nakauchi, H., Yamamoto, M., Groudine, M., et al. (1998) · The EMBO Journal

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 190

The β-Globin LCR Is Not Necessary for an Open Chromatin Structure or Developmentally Regulated Transcription of the Native Mouse β-Globin Locus

Epner, E., Reik, A., Cimbora, D., Telling, A., Bender, M. A., Fiering, S., Enver, T., Martin, D. I. K., Kennedy, M., Keller, G., et al. (1998) · Molecular Cell

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 183

Genomic Targeting of Methylated DNA: Influence of Methylation on Transcription, Replication, Chromatin Structure, and Histone Acetylation

Schübeler, D., Lorincz, M. C., Cimbora, D. M., Telling, A., Feng, Y.-Q., Bouhassira, E. E., & Groudine, M. (2000) · Molecular and Cellular Biology

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 165

The Locus Control Region Is Necessary for Gene Expression in the Human β-Globin Locus but Not the Maintenance of an Open Chromatin Structure in Erythroid Cells

Reik, A., Telling, A., Zitnik, G., Cimbora, D., Epner, E., & Groudine, M. (1998) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 163

The murine β-globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes

Schübeler, D., Groudine, M., & Bender, M. A. (2001) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 87

Molecular basis for chromatin binding and regulation of MLL5

Ali, M., Rincón-Arano, H., Zhao, W., Rothbart, S. B., Tong, Q., Parkhurst, S. M., Strahl, B. D., Deng, L.-W., Groudine, M., & Kutateladze, T. G. (2013) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsCancer-related gene regulation

Cited by 84

Flanking HS-62.5 and 3′ HS1, and regions upstream of the LCR, are not required for β-globin transcription

Bender, M. A., Byron, R., Ragoczy, T., Telling, A., Bulger, M., & Groudine, M. (2006) · Blood

Hemoglobinopathies and Related DisordersGenomics and Chromatin Dynamics

Cited by 59

The hypersensitive sites of the murine β-globin locus control region act independently to affect nuclear localization and transcriptional elongation

Bender, M. A., Ragoczy, T., Lee, J., Byron, R., Telling, A., Dean, A., & Groudine, M. (2012) · Blood

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 53