Joyce, Gerald F.

The antiquity of RNA-based evolution.

Joyce, G. F. (2002) · Nature

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 1,070

A 1.7-kilobase single-stranded DNA that folds into a nanoscale octahedron

Shih, W. M., Quispe, J. D., & Joyce, G. F. (2004) · Nature

Advanced biosensing and bioanalysis techniquesDNA and Biological Computing

Cited by 989

Self-Sustained Replication of an RNA Enzyme

Lincoln, T. A., & Joyce, G. F. (2009) · Science

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 670

RNA evolution and the origins of life

Joyce, G. F. (1989) · Nature

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 658

The origins of the RNA world

Robertson, M. P., & Joyce, G. F. (2012) · Cold Spring Harbor Perspectives in Biology

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 556

Directed Evolution of Nucleic Acid Enzymes

Joyce, G. F. (2004) · Annual Review of Biochemistry

RNA and protein synthesis mechanismsDNA and Nucleic Acid Chemistry

Cited by 515

Chiral selection in poly(C)-directed synthesis of oligo(G)

Joyce, G. F., Visser, G. M., van Boeckel, C. A. A., van Boom, J. H., Orgel, L. E., & van Westrenen, J. (1984) · Nature

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 398

The case for an ancestral genetic system involving simple analogues of the nucleotides.

Joyce, G. F., Schwartz, A. W., Miller, S. L., & Orgel, L. E. (1987) · Proceedings of the National Academy of Sciences

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 387

Protocells and RNA Self-Replication

Joyce, G. F., & Szostak, J. W. (2018) · Cold Spring Harbor Perspectives in Biology

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 308

A self-replicating ligase ribozyme

Paul, N., & Joyce, G. F. (2002) · Proceedings of the National Academy of Sciences

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 264

Amplification of RNA by an RNA polymerase ribozyme

Horning, D. P., & Joyce, G. F. (2016) · Proceedings of the National Academy of Sciences

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 261

Production of RNA by a polymerase protein encapsulated within phospholipid vesicles

Chakrabarti, A. C., Breaker, R. R., Joyce, G. F., & Deamer, D. W. (1994) · Journal of Molecular Evolution

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 196

A cross-chiral RNA polymerase ribozyme

Sczepanski, J. T., & Joyce, G. F. (2014) · Nature

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 186

Non-enzymatic template-directed synthesis on RNA random copolymers

Joyce, G. F., Inoue, T., & Orgel, L. E. (1984) · Journal of Molecular Biology

DNA and Nucleic Acid ChemistryRNA and protein synthesis mechanisms

Cited by 178

Selective Derivatization and Sequestration of Ribose from a Prebiotic Mix

Springsteen, G., & Joyce, G. F. (2004) · Journal of the American Chemical Society

Origins and Evolution of LifeCarbohydrate Chemistry and Synthesis

Cited by 122

Nonenzymatic Template-directed Synthesis of Informational Macromolecules

Joyce, G. F. (1987) · Cold Spring Harbor Symposia on Quantitative Biology

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 121

An RNA polymerase ribozyme that synthesizes its own ancestor

Tjhung, K. F., Shokhirev, M. N., Horning, D. P., & Joyce, G. F. (2020) · Proceedings of the National Academy of Sciences

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 121

Highly Efficient Self-Replicating RNA Enzymes

Robertson, M. P., & Joyce, G. F. (2014) · Chemistry & Biology

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 105

A ribozyme composed of only two different nucleotides

Reader, J. S., & Joyce, G. F. (2002) · Nature

RNA and protein synthesis mechanismsOrigins and Evolution of Life

Cited by 100

A ribozyme that lacks cytidine

Rogers, J., & Joyce, G. F. (1999) · Nature

RNA and protein synthesis mechanismsOrigins and Evolution of Life

Cited by 94

Template-directed synthesis on the pentanucleotide CpCpGpCpC

Inoue, T., Joyce, G. F., Grzeskowiak, K., Orgel, L. E., Brown, J. M., & Reese, C. B. (1984) · Journal of Molecular Biology

DNA and Nucleic Acid ChemistryRNA and protein synthesis mechanisms

Cited by 80

A reverse transcriptase ribozyme

Samanta, B., & Joyce, G. F. (2017) · eLife

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 57

Bit by bit: The Darwinian basis of life

Joyce, G. F. (2012) · PLoS Biology

Origins and Evolution of LifeSpace Science and Extraterrestrial Life

Cited by 45

Thermal Habitat for RNA Amplification and Accumulation

Salditt, A., Keil, L. M. R., Horning, D. P., Mast, C. B., Joyce, G. F., & Braun, D. (2020) · Physical Review Letters

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 44