Aikawa, Elena

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Théry, C., Witwer, K. W., Aikawa, E., Alcaraz, M. J., Anderson, J. D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin‐Smith, G. K., et al. (2018) · Journal of Extracellular Vesicles

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 11,099

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

Nahrendorf, M., Swirski, F. K., Aikawa, E., Stangenberg, L., Wurdinger, T., Figueiredo, J.-L., Libby, P., Weissleder, R., & Pittet, M. J. (2007) · The Journal of Experimental Medicine

Cardiac Fibrosis and RemodelingAtherosclerosis and Cardiovascular Diseases

Cited by 2,300

Identification of splenic reservoir monocytes and their deployment to inflammatory sites

Swirski, F. K., Nahrendorf, M., Etzrodt, M., Wildgruber, M., Cortez-Retamozo, V., Panizzi, P., Figueiredo, J.-L., Kohler, R. H., Chudnovskiy, A., Waterman, P., et al. (2009) · Science

Immune cells in cancerAtherosclerosis and Cardiovascular Diseases

Cited by 2,221

Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

Kalra, H., Simpson, R. J., Ji, H., Aikawa, E., Altevogt, P., Askenase, P., Bond, V. C., Borràs, F. E., Breakefield, X., Budnik, V., et al. (2012) · PLoS Biology

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 1,367

Calcific Aortic Valve Disease: Not Simply a Degenerative Process: A Review and Agenda for Research From the National Heart and Lung and Blood Institute Aortic Stenosis Working Group Executive Summary: Calcific Aortic Valve Disease – 2011 Update

Rajamannan, N. M., Evans, F. J., Aikawa, E., Grande-Allen, K. J., Demer, L. L., Heistad, D. D., Simmons, C. A., Masters, K. S., Mathieu, P., O'Brien, K. D., et al. (2011) · Circulation

Cardiac Valve Diseases and TreatmentsCardiac Imaging and Diagnostics

Cited by 842

Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis

Nahrendorf, M., Jaffer, F. A., Kelly, K. A., Sosnovik, D. E., Aikawa, E., Libby, P., & Weissleder, R. (2006) · Circulation

Atherosclerosis and Cardiovascular DiseasesCerebrovascular and Carotid Artery Diseases

Cited by 602

Nanoparticle PET-CT Imaging of Macrophages in Inflammatory Atherosclerosis

Nahrendorf, M., Zhang, H., Hembrador, S., Panizzi, P., Sosnovik, D. E., Aikawa, E., Libby, P., Swirski, F. K., & Weissleder, R. (2008) · Circulation

Cardiac Imaging and DiagnosticsRadiopharmaceutical Chemistry and Applications

Cited by 559

Macrophage-Derived Matrix Vesicles: An Alternative Novel Mechanism for Microcalcification in Atherosclerotic Plaques

New, S. E. P., Goettsch, C., Aikawa, M., Marchini, J. F., Shibasaki, M., Yabusaki, K., Libby, P., Shanahan, C. M., Croce, K., & Aikawa, E. (2013) · Circulation Research

Parathyroid Disorders and TreatmentsExtracellular vesicles in disease

Cited by 451

Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques

Hutcheson, J. D., Goettsch, C., Bertazzo, S., Maldonado, N., Ruiz, J. L., Goh, W., Yabusaki, K., Faits, T., Bouten, C., Franck, G., et al. (2016) · Nature Materials

Calcium Carbonate Crystallization and InhibitionDermatological and Skeletal Disorders

Cited by 419

Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease

Swirski, F. K., Pittet, M. J., Kircher, M. F., Aikawa, E., Jaffer, F. A., Libby, P., & Weissleder, R. (2006) · Proceedings of the National Academy of Sciences

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 367

Calcific aortic valve disease: from molecular and cellular mechanisms to medical therapy

Kraler, S., Blaser, M. C., Aikawa, E., Camici, G. G., & Lüscher, T. F. (2022) · European Heart Journal

Cardiac Valve Diseases and TreatmentsCardiac Imaging and Diagnostics

Cited by 281

Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease

Schlotter, F., Halu, A., Goto, S., Blaser, M. C., Body, S. C., Lee, L. H., Higashi, H., DeLaughter, D. M., Hutcheson, J. D., Vyas, P., et al. (2018) · Circulation

Cardiac Valve Diseases and TreatmentsAdvanced Proteomics Techniques and Applications

Cited by 256

Multiomics of Tissue Extracellular Vesicles Identifies Unique Modulators of Atherosclerosis and Calcific Aortic Valve Stenosis

Blaser, M. C., Buffolo, F., Halu, A., Turner, M. E., Schlotter, F., Higashi, H., Pantano, L., Clift, C. L., Saddic, L. A., Atkins, S. K., et al. (2023) · Circulation

Extracellular vesicles in diseaseAtherosclerosis and Cardiovascular Diseases

Cited by 114

Multi-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis

Blaser, M. C., Kraler, S., Lüscher, T. F., & Aikawa, E. (2021) · Circulation Research

Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment Approaches

Cited by 109

Phosphate in Cardiovascular Disease: From New Insights Into Molecular Mechanisms to Clinical Implications

Turner, M. E., Beck, L., Hill Gallant, K. M., Chen, Y., Moe, O. W., Kuro-o, M., Moe, S. M., & Aikawa, E. (2024) · Arteriosclerosis, Thrombosis, and Vascular Biology

Parathyroid Disorders and TreatmentsAlkaline Phosphatase Research Studies

Cited by 54

ApoC-III is a novel inducer of calcification in human aortic valves

Schlotter, F., de Freitas, R. C. C., Rogers, M. A., Blaser, M. C., Wu, P.-J., Higashi, H., Halu, A., Iqbal, F., Andraski, A. B., Rodia, C. N., et al. (2021) · Journal of Biological Chemistry

Cardiac Valve Diseases and TreatmentsAtherosclerosis and Cardiovascular Diseases

Cited by 49

Calcific aortic stenosis: omics-based target discovery and therapy development

Blaser, M. C., Bäck, M., Lüscher, T. F., & Aikawa, E. (2025) · European Heart Journal

Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment Approaches

Cited by 45

Macrophage heterogeneity and efferocytosis: Beyond the M1/M2 dichotomy

Kumar Jha, P., Aikawa, M., & Aikawa, E. (2024) · Circulation Research

Phagocytosis and Immune RegulationImmune cells in cancer

Cited by 45

Large-scale proteomics identifies novel biomarkers and circulating risk factors for aortic stenosis

Shelbaya, K., Arthur, V., Yang, Y., Dorbala, P., Buckley, L., Claggett, B., Skali, H., Dufresne, L., Yang, T.-Y., Engert, J. C., et al. (2024) · Journal of the American College of Cardiology

Cardiac Valve Diseases and TreatmentsAdvanced Proteomics Techniques and Applications

Cited by 41

Network-guided multiomic mapping of aortic valve calcification

Blaser, M. C., Kraler, S., Lüscher, T. F., & Aikawa, E. (2023) · Arteriosclerosis, Thrombosis, and Vascular Biology

Cardiac Valve Diseases and TreatmentsBioinformatics and Genomic Networks

Cited by 16

A HIGHLY SELECTIVE PPARα AGONIST K-877 SUPPRESSES NEOINTIMA FORMATION FOLLOWING CORONARY STENTING IN SWINE

Iwata, H., Osborn, E., Ughi, G., Murakami, K., Goettsch, C., Hutcheson, J., Mauskapf, A., Mattson, P., Libby, P., Aikawa, E., et al. (2016) · Journal of the American College of Cardiology

Coronary Interventions and DiagnosticsPeroxisome Proliferator-Activated Receptors

Cited by 2