Hughes, Alun D.

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

Min, J. L., Hemani, G., Hannon, E., Dekkers, K. F., Castillo-Fernandez, J., Luijk, R., Carnero-Montoro, E., Lawson, D. J., Burrows, K., Suderman, M., et al. (2021) · Nature Genetics

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 506

Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial

Petrie, J. R., Chaturvedi, N., Ford, I., Brouwers, M. C. G. J., Greenlaw, N., Tillin, T., Hramiak, I., Hughes, A. D., Jenkins, A. J., Klein, B. E. K., et al. (2017) · The Lancet Diabetes & Endocrinology

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 357

Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose

Reynolds, C. J., Pade, C., Gibbons, J. M., Butler, D. K., Otter, A. D., Menacho, K., Fontana, M., Smit, A., Sackville-West, J. E., Cutino-Moguel, T., et al. (2021) · Science

SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations

Cited by 338

Differences in smoking associated DNA methylation patterns in south asians and europeans

Elliott, H. R., Tillin, T., McArdle, W. L., Ho, K., Duggirala, A., Frayling, T. M., Davey Smith, G., Hughes, A. D., Chaturvedi, N., & Relton, C. L. (2014) · Clinical Epigenetics

Epigenetics and DNA MethylationSmoking Behavior and Cessation

Cited by 282

Accuracy of Cuff-Measured Blood Pressure

Picone, D. S., Schultz, M. G., Otahal, P., Aakhus, S., Al-Jumaily, A. M., Black, J. A., Bos, W. J., Chambers, J. B., Chen, C.-H., Cheng, H.-M., et al. (2017) · Journal of the American College of Cardiology

Blood Pressure and Hypertension StudiesCardiovascular Health and Disease Prevention

Cited by 277

Validation of non-invasive central blood pressure devices: ARTERY Society task force consensus statement on protocol standardization

Sharman, J. E., Avolio, A. P., Baulmann, J., Benetos, A., Blacher, J., Blizzard, C. L., Boutouyrie, P., Chen, C.-H., Chowienczyk, P., Cockcroft, J. R., et al. (2017) · European Heart Journal

Cardiovascular Health and Disease PreventionBlood Pressure and Hypertension Studies

Cited by 231

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase

Würtz, P., Wang, Q., Soininen, P., Kangas, A. J., Fatemifar, G., Tynkkynen, T., Tiainen, M., Perola, M., Tillin, T., Hughes, A. D., et al. (2016) · Journal of the American College of Cardiology

Lipoproteins and Cardiovascular HealthMetabolomics and Mass Spectrometry Studies

Cited by 188

Ethnicity and prediction of cardiovascular disease: performance of QRISK2 and Framingham scores in a UK tri-ethnic prospective cohort study (SABRE—Southall And Brent REvisited)

Tillin, T., Hughes, A. D., Whincup, P., Mayet, J., Sattar, N., McKeigue, P. M., Chaturvedi, N., & On behalf of the SABRE Study Group (2014) · Heart

Health Promotion and Cardiovascular PreventionLipoproteins and Cardiovascular Health

Cited by 130

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

Wild, P. S., Felix, J. F., Schillert, A., Teumer, A., Chen, M.-H., Leening, M. J. G., Völker, U., Großmann, V., Brody, J. A., Irvin, M. R., et al. (2017) · Journal of Clinical Investigation

Genetic Associations and EpidemiologyCardiac electrophysiology and arrhythmias

Cited by 129

Hypertensive Disorders of Pregnancy and Offspring Cardiac Structure and Function in Adolescence

Timpka, S., Macdonald‐Wallis, C., Hughes, A. D., Chaturvedi, N., Franks, P. W., Lawlor, D. A., & Fraser, A. (2016) · Journal of the American Heart Association

Pregnancy and preeclampsia studiesBirth, Development, and Health

Cited by 106

Wave intensity analysis and the development of the reservoir–wave approach

Tyberg, J. V., Davies, J. E., Wang, Z., Whitelaw, W. A., Flewitt, J. A., Shrive, N. G., Francis, D. P., Hughes, A. D., Parker, K. H., & Wang, J.-J. (2009) · Medical & Biological Engineering & Computing

Cardiovascular Health and Disease PreventionElasticity and Material Modeling

Cited by 104

Meta‐analysis of the comparative effects of different classes of antihypertensive agents on brachial and central systolic blood pressure, and augmentation index

Manisty, C. H., & Hughes, A. D. (2013) · British Journal of Clinical Pharmacology

Cardiovascular Health and Disease PreventionBlood Pressure and Hypertension Studies

Cited by 99

Ethnic differences in associations between blood pressure and stroke in south Asian and European men

Eastwood, S. V., Tillin, T., Chaturvedi, N., & Hughes, A. D. (2015) · Hypertension

Blood Pressure and Hypertension StudiesCardiovascular Health and Disease Prevention

Cited by 82

Thigh fat and muscle each contribute to excess cardiometabolic risk in SouthAsians, independent of visceral adipose tissue

Eastwood, S. V., Tillin, T., Wright, A., Mayet, J., Godsland, I., Forouhi, N. G., Whincup, P., Hughes, A. D., & Chaturvedi, N. (2014) · Obesity

Diabetes, Cardiovascular Risks, and LipoproteinsCardiovascular Disease and Adiposity

Cited by 61

Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition

Kettunen, J., Holmes, M. V., Allara, E., Anufrieva, O., Ohukainen, P., Oliver-Williams, C., Wang, Q., Tillin, T., Hughes, A. D., Kähönen, M., et al. (2019) · PLOS Biology

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 47

Improved Exercise-Related Skeletal Muscle Oxygen Consumption Following Uptake of Endurance Training Measured Using Near-Infrared Spectroscopy

Jones, S., D'Silva, A., Bhuva, A., Lloyd, G., Manisty, C., Moon, J. C., Sharma, S., & Hughes, A. D. (2017) · Frontiers in Physiology

Cardiovascular and exercise physiologySports Performance and Training

Cited by 47

Circulating apolipoprotein E concentration and cardiovascular disease risk: meta-analysis of results from three studies

Sofat, R., Cooper, J. A., Kumari, M., Casas, J. P., Mitchell, J. P., Acharya, J., Thom, S., Hughes, A. D., Humphries, S. E., & Hingorani, A. D. (2016) · PLOS Medicine

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 42

Association between resting heart rate across the life course and all-cause mortality: Longitudinal findings from the Medical Research Council (MRC) National Survey of Health and Development (NSHD)

Ó Hartaigh, B., Gill, T. M., Shah, I., Hughes, A. D., Deanfield, J. E., Kuh, D., & Hardy, R. (2014) · Journal of Epidemiology and Community Health

Heart Rate Variability and Autonomic ControlHeart rate and cardiovascular health

Cited by 40

Associations between left ventricular dysfunction and brain structure and function: findings from the SABRE (Southall and Brent Revisited) study

Park, C. M., Williams, E. D., Chaturvedi, N., Tillin, T., Stewart, R. J., Richards, M., Shibata, D., Mayet, J., & Hughes, A. D. (2017) · Journal of the American Heart Association

Dementia and Cognitive Impairment ResearchCardiovascular Function and Risk Factors

Cited by 31

Masked hypertension and submaximal exercise blood pressure among adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC)

Huang, Z., Sharman, J. E., Fonseca, R., Park, C., Chaturvedi, N., Davey Smith, G., Howe, L. D., Lawlor, D. A., Hughes, A. D., & Schultz, M. G. (2020) · Scandinavian Journal of Medicine & Science in Sports

Blood Pressure and Hypertension StudiesCardiovascular Health and Disease Prevention

Cited by 27

Submaximal exercise blood pressure and cardiovascular structure in adolescence

Schultz, M. G., Park, C., Fraser, A., Howe, L. D., Jones, S., Rapala, A., Davey Smith, G., Sharman, J. E., Lawlor, D. A., Chaturvedi, N., et al. (2019) · International Journal of Cardiology

Cardiovascular Health and Disease PreventionCardiovascular and exercise physiology

Cited by 15

The influence of fitness on exercise blood pressure and its association with cardiac structure in adolescence

Huang, Z., Fonseca, R., Sharman, J. E., Park, C., Chaturvedi, N., Howe, L. D., Hughes, A. D., & Schultz, M. G. (2020) · Scandinavian Journal of Medicine & Science in Sports

Cardiovascular and exercise physiologyCardiovascular Effects of Exercise

Cited by 13