Russell, David W.

The Enzymes, Regulation, and Genetics of Bile Acid Synthesis

Russell, D. W. (2003) · Annual Review of Biochemistry

Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms

Cited by 2,069

Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System

Goldstein, J. L., Brown, M. S., Anderson, R. G. W., Russell, D. W., & Schneider, W. J. (1985) · Annual Review of Cell Biology

Cellular transport and secretionCholesterol and Lipid Metabolism

Cited by 1,600

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

Yamamoto, T., Davis, C. G., Brown, M. S., Schneider, W. J., Casey, M. L., Goldstein, J. L., & Russell, D. W. (1984) · Cell

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 1,382

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells.

Tian, H., McKnight, S. L., & Russell, D. W. (1997) · Genes & Development

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

Cited by 1,351

Steroid 5α-reductase: two genes/two enzymes

Russell, D. W., & Wilson, J. D. (1994) · Annual Review of Biochemistry

Steroid Chemistry and BiochemistryProstate Cancer Treatment and Research

Cited by 1,105

Purification of Nucleic Acids by Extraction with Phenol:Chloroform

Sambrook, J., & Russell, D. W. (2006) · Cold Spring Harbor Protocols

Molecular Biology Techniques and ApplicationsDNA and Nucleic Acid Chemistry

Cited by 1,047

Bile acid biosynthesis

Russell, D. W., & Setchell, K. D. R. (1992) · Biochemistry

Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms

Cited by 819

Tissue distribution and ontogeny of steroid 5 alpha-reductase isozyme expression.

Thigpen, A. E., Silver, R. I., Guileyardo, J. M., Casey, M. L., McConnell, J. D., & Russell, D. W. (1993) · Journal of Clinical Investigation

Sexual Differentiation and DisordersHair Growth and Disorders

Cited by 727

cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain

Lund, E. G., Guileyardo, J. M., & Russell, D. W. (1999) · Proceedings of the National Academy of Sciences

Cholesterol and Lipid MetabolismSteroid Chemistry and Biochemistry

Cited by 668

The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

Tian, H., Hammer, R. E., Matsumoto, A. M., Russell, D. W., & McKnight, S. L. (1998) · Genes & Development

Congenital heart defects researchNeuroscience of respiration and sleep

Cited by 647

Deletion of steroid 5α-reductase 2 gene in male pseudohermaphroditism

Andersson, S., Berman, D. M., Jenkins, E. P., & Russell, D. W. (1991) · Nature

Sexual Differentiation and DisordersGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Cited by 643

Male pseudohermaphroditism caused by mutations of testicular 17β-hydroxysteroid dehydrogenase 3

Geissler, W. M., Davis, D. L., Wu, L., Bradshaw, K. D., Patel, S., Mendonca, B. B., Elliston, K. O., Wilson, J. D., Russell, D. W., & Andersson, S. (1994) · Nature Genetics

Sexual Differentiation and DisordersGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Cited by 570

Structural and biochemical properties of cloned and expressed human and rat steroid 5 alpha-reductases

Andersson, S., & Russell, D. W. (1990) · Proceedings of the National Academy of Sciences

Prostate Cancer Treatment and ResearchUrinary Bladder and Prostate Research

Cited by 501

25-Hydroxycholesterol suppresses interleukin-1–driven inflammation downstream of type I interferon

Reboldi, A., Dang, E. V., McDonald, J. G., Liang, G., Russell, D. W., & Cyster, J. G. (2014) · Science

interferon and immune responsesInflammasome and immune disorders

Cited by 444

Molecular genetics of steroid 5 alpha-reductase 2 deficiency

Thigpen, A. E., Davis, D. L., Milatovich, A., Mendonca, B. B., Imperato-McGinley, J., Griffin, J. E., Francke, U., Wilson, J. D., & Russell, D. W. (1992) · Journal of Clinical Investigation

Sexual Differentiation and DisordersUrological Disorders and Treatments

Cited by 422

Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover

Lund, E. G., Xie, C., Kotti, T., Turley, S. D., Dietschy, J. M., & Russell, D. W. (2003) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismSteroid Chemistry and Biochemistry

Cited by 421

Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region

Davis, C. G., Goldstein, J. L., Südhof, T. C., Anderson, R. G. W., Russell, D. W., & Brown, M. S. (1987) · Nature

Cholesterol and Lipid MetabolismCellular transport and secretion

Cited by 411

Genetic and pharmacological evidence for more than one human steroid 5 alpha-reductase.

Jenkins, E. P., Andersson, S., Imperato-McGinley, J., Wilson, J. D., & Russell, D. W. (1992) · Journal of Clinical Investigation

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 395

Tissue distribution and kinetic characteristics of rat steroid 5 alpha-reductase isozymes. Evidence for distinct physiological functions.

Normington, K., & Russell, D. W. (1992) · Journal of Biological Chemistry

Prostate Cancer Treatment and ResearchSteroid Chemistry and Biochemistry

Cited by 379

Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7alpha-hydroxylase gene causes severe neonatal liver disease.

Setchell, K. D., Schwarz, M., O'Connell, N. C., Lund, E. G., Davis, D. L., Lathe, R., Thompson, H. R., Weslie Tyson, R., Sokol, R. J., & Russell, D. W. (1998) · Journal of Clinical Investigation

Metabolism and Genetic DisordersCholesterol and Lipid Metabolism

Cited by 375

Biomarkers of NAFLD progression: a lipidomics approach to an epidemic

Gorden, D. L., Myers, D. S., Ivanova, P. T., Fahy, E., Maurya, M. R., Gupta, S., Min, J., Spann, N. J., McDonald, J. G., Kelly, S. L., et al. (2015) · Journal of Lipid Research

Liver Disease Diagnosis and TreatmentMetabolomics and Mass Spectrometry Studies

Cited by 372

Fifty years of advances in bile acid synthesis and metabolism

Russell, D. W. (2009) · Journal of Lipid Research

Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms

Cited by 358

Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation

Dang, E. V., McDonald, J. G., Russell, D. W., & Cyster, J. G. (2017) · Cell

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 348

Steroid 5α-Reductase 2 Deficiency*

WILSON, J. D., GRIFFIN, J. E., & RUSSELL, D. W. (1993) · Endocrine Reviews

Sexual Differentiation and DisordersUrological Disorders and Treatments

Cited by 346