Chen, Alon

Overshadowed by the amygdala: The bed nucleus of the stria terminalis emerges as key to psychiatric disorders

Lebow, M. A., & Chen, A. (2016) · Molecular Psychiatry

Memory and Neural MechanismsStress Responses and Cortisol

Cited by 660

Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice

Elliott, E., Ezra-Nevo, G., Regev, L., Neufeld-Cohen, A., & Chen, A. (2010) · Nature Neuroscience

Stress Responses and CortisolEpigenetics and DNA Methylation

Cited by 436

The Role of m6A/m-RNA Methylation in Stress Response Regulation

Engel, M., Eggert, C., Kaplick, P. M., Eder, M., Röh, S., Tietze, L., Namendorf, C., Arloth, J., Weber, P., Rex-Haffner, M., et al. (2018) · Neuron

RNA modifications and cancerRNA regulation and disease

Cited by 411

MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity

Issler, O., Haramati, S., Paul, E. D., Maeno, H., Navon, I., Zwang, R., Gil, S., Mayberg, H. S., Dunlop, B. W., Menke, A., et al. (2014) · Neuron

Treatment of Major DepressionMicroRNA in disease regulation

Cited by 318

Resilience to Chronic Stress Is Mediated by Hippocampal Brain-Derived Neurotrophic Factor

Taliaz, D., Loya, A., Gersner, R., Haramati, S., Chen, A., & Zangen, A. (2011) · The Journal of Neuroscience

Stress Responses and CortisolTreatment of Major Depression

Cited by 311

Determining the role of microRNAs in psychiatric disorders

Issler, O., & Chen, A. (2015) · Nature Reviews Neuroscience

MicroRNA in disease regulationGenetics and Neurodevelopmental Disorders

Cited by 309

microRNA as Repressors of Stress-Induced Anxiety: The Case of Amygdalar miR-34

Haramati, S., Navon, I., Issler, O., Ezra-Nevo, G., Gil, S., Zwang, R., Hornstein, E., & Chen, A. (2011) · The Journal of Neuroscience

MicroRNA in disease regulationStress Responses and Cortisol

Cited by 252

High-order social interactions in groups of mice

Shemesh, Y., Sztainberg, Y., Forkosh, O., Shlapobersky, T., Chen, A., & Schneidman, E. (2013) · eLife

Animal Behavior and ReproductionPrimate Behavior and Ecology

Cited by 213

Chronic Stress Induces Sex-Specific Alterations in Methylation and Expression of Corticotropin-Releasing Factor Gene in the Rat

Sterrenburg, L., Gaszner, B., Boerrigter, J., Santbergen, L., Bramini, M., Elliott, E., Chen, A., Peeters, B. W. M. M., Roubos, E. W., & Kozicz, T. (2011) · PLoS ONE

Stress Responses and CortisolEpigenetics and DNA Methylation

Cited by 149

Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function

Balsevich, G., Häusl, A. S., Meyer, C. W., Karamihalev, S., Feng, X., Pöhlmann, M. L., Dournes, C., Uribe-Marino, A., Santarelli, S., Labermaier, C., et al. (2017) · Nature Communications

Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases

Cited by 134

Prolonged and site-specific over-expression of corticotropin-releasing factor reveals differential roles for extended amygdala nuclei in emotional regulation

Regev, L., Neufeld-Cohen, A., Tsoory, M., Kuperman, Y., Getselter, D., Gil, S., & Chen, A. (2011) · Molecular Psychiatry

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 110

Identity domains capture individual differences from across the behavioral repertoire

Forkosh, O., Karamihalev, S., Roeh, S., Alon, U., Anpilov, S., Touma, C., Nussbaumer, M., Flachskamm, C., Kaplick, P. M., Shemesh, Y., et al. (2019) · Nature Neuroscience

Animal Behavior and ReproductionNeurotransmitter Receptor Influence on Behavior

Cited by 110

Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties

Hartmann, J., Wagner, K. V., Gaali, S., Kirschner, A., Kozany, C., Ruhter, G., Dedic, N., Hausl, A. S., Hoeijmakers, L., Westerholz, S., et al. (2015) · Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 109

Ucn3 and CRF-R2 in the medial amygdala regulate complex social dynamics

Shemesh, Y., Forkosh, O., Mahn, M., Anpilov, S., Sztainberg, Y., Manashirov, S., Shlapobersky, T., Elliott, E., Tabouy, L., Ezra, G., et al. (2016) · Nature Neuroscience

Neuroendocrine regulation and behaviorStress Responses and Cortisol

Cited by 99

Sex differences: Transcriptional signatures of stress exposure in male and female brains

Brivio, E., Lopez, J. P., & Chen, A. (2020) · Genes, Brain and Behavior

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 95

Site-Specific Genetic Manipulation of Amygdala Corticotropin-Releasing Factor Reveals Its Imperative Role in Mediating Behavioral Response to Challenge

Regev, L., Tsoory, M., Gil, S., & Chen, A. (2012) · Biological Psychiatry

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 93

Wireless Optogenetic Stimulation of Oxytocin Neurons in a Semi-natural Setup Dynamically Elevates Both Pro-social and Agonistic Behaviors

Anpilov, S., Shemesh, Y., Eren, N., Harony-Nicolas, H., Benjamin, A., Dine, J., Oliveira, V. E. M., Forkosh, O., Karamihalev, S., Hüttl, R.-E., et al. (2020) · Neuron

Neuroendocrine regulation and behaviorNeurotransmitter Receptor Influence on Behavior

Cited by 89

miR-323a regulates ERBB4 and is involved in depression

Fiori, L. M., Kos, A., Lin, R., Théroux, J.-F., Lopez, J. P., Kühne, C., Eggert, C., Holzapfel, M., Huettl, R.-E., Mechawar, N., et al. (2021) · Molecular Psychiatry

MicroRNA in disease regulationTreatment of Major Depression

Cited by 88

Perifornical Urocortin-3 mediates the link between stress-induced anxiety and energy homeostasis

Kuperman, Y., Issler, O., Regev, L., Musseri, I., Navon, I., Neufeld-Cohen, A., Gil, S., & Chen, A. (2010) · Proceedings of the National Academy of Sciences

Neuropeptides and Animal PhysiologyRegulation of Appetite and Obesity

Cited by 81

Dnmt3a in the Medial Prefrontal Cortex Regulates Anxiety-Like Behavior in Adult Mice

Elliott, E., Manashirov, S., Zwang, R., Gil, S., Tsoory, M., Shemesh, Y., & Chen, A. (2016) · The Journal of Neuroscience

Epigenetics and DNA MethylationStress Responses and Cortisol

Cited by 78

Heterozygosity for the mood disorder-associated variant Gln460Arg alters P2X7 receptor function and sleep quality

Metzger, M. W., Walser, S. M., Dedic, N., Aprile-Garcia, F., Jakubcakova, V., Adamczyk, M., Webb, K. J., Uhr, M., Refojo, D., Schmidt, M. V., et al. (2017) · The Journal of Neuroscience

Adenosine and Purinergic SignalingNeurotransmitter Receptor Influence on Behavior

Cited by 59

Neutrophil to-lymphocyte and platelet-to-lymphocyte ratios as biomarkers for suicidal behavior in children and adolescents with depression or anxiety treated with selective serotonin reuptake inhibitors

Amitai, M., Kaffman, S., Kroizer, E., Lebow, M., Magen, I., Benaroya-Milshtein, N., Fennig, S., Weizman, A., Apter, A., & Chen, A. (2022) · Brain, Behavior, and Immunity

Suicide and Self-Harm StudiesTryptophan and brain disorders

Cited by 51

Oligonucleotides as therapeutic tools for brain disorders: Focus on major depressive disorder and Parkinson’s disease.

Bortolozzi, A., Manashirov, S., Chen, A., & Artigas, F. (2021) · Pharmacology & Therapeutics

RNA Interference and Gene DeliveryTreatment of Major Depression

Cited by 37

Genetic approach for intracerebroventricular delivery

Regev, L., Ezrielev, E., Gershon, E., Gil, S., & Chen, A. (2010) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 35