Rader, Daniel J.

A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

Vujkovic, M., Ramdas, S., Lorenz, K. M., Guo, X., Darlay, R., Cordell, H. J., He, J., Gindin, Y., Chung, C., Myers, R. P., et al. (2022) · Nature Genetics

Liver Disease Diagnosis and TreatmentGenetic Associations and Epidemiology

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Association of rare and common variation in the lipoprotein lipase gene with coronary artery disease

Khera, A. V., Won, H.-H., Peloso, G. M., O’Dushlaine, C., Liu, D., Stitziel, N. O., Natarajan, P., Nomura, A., Emdin, C. A., Gupta, N., et al. (2017) · JAMA

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

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Macrophage Sortilin Promotes LDL Uptake, Foam Cell Formation, and Atherosclerosis

Patel, K. M., Strong, A., Tohyama, J., Jin, X., Morales, C. R., Billheimer, J., Millar, J., Kruth, H., & Rader, D. J. (2015) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 194

Cascade Screening for Familial Hypercholesterolemia and the Use of Genetic Testing

Knowles, J. W., Rader, D. J., & Khoury, M. J. (2017) · JAMA

Lipoproteins and Cardiovascular HealthGenomics and Rare Diseases

Cited by 190

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., Helgadottir, A., Magnusdottir, A., Jonasdottir, A., Gretarsdottir, S., et al. (2016) · New England Journal of Medicine

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 189

Measures of Insulin Resistance Add Incremental Value to the Clinical Diagnosis of Metabolic Syndrome in Association With Coronary Atherosclerosis

Reilly, M. P., Wolfe, M. L., Rhodes, T., Girman, C., Mehta, N., & Rader, D. J. (2004) · Circulation

Diabetes, Cardiovascular Risks, and LipoproteinsCardiac Imaging and Diagnostics

Cited by 185

Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India

Saxena, R., Saleheen, D., Been, L. F., Garavito, M. L., Braun, T., Bjonnes, A., Young, R., Ho, W. K., Rasheed, A., Frossard, P., et al. (2013) · Diabetes

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 185

Genomics and phenomics of body mass index reveals a complex disease network

Huang, J., Huffman, J. E., Huang, Y., Do Valle, Í., Assimes, T. L., Raghavan, S., Voight, B. F., Liu, C., Barabási, A.-L., Huang, R. D. L., et al. (2022) · Nature Communications

Genetic Associations and EpidemiologyGenetics and Physical Performance

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A randomized study comparing the effects of a low-carbohydrate diet and a conventional diet on lipoprotein subfractions and C-reactive protein levels in patients with severe obesity

Seshadri, P., Iqbal, N., Stern, L., Williams, M., Chicano, K. L., Daily, D. A., McGrory, J., Gracely, E. J., Rader, D. J., & Samaha, F. F. (2004) · The American Journal of Medicine

Diet and metabolism studiesDietary Effects on Health

Cited by 169

Tolerability of Red Yeast Rice (2,400 mg Twice Daily) Versus Pravastatin (20 mg Twice Daily) in Patients With Previous Statin Intolerance

Halbert, S. C., French, B., Gordon, R. Y., Farrar, J. T., Schmitz, K., Morris, P. B., Thompson, P. D., Rader, D. J., & Becker, D. J. (2010) · The American Journal of Cardiology

Lipoproteins and Cardiovascular HealthNatural Products and Biological Research

Cited by 154

Novel HDL-directed pharmacotherapeutic strategies

deGoma, E. M., & Rader, D. J. (2011) · Nature Reviews Cardiology

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 149

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Voight, B. F., Peloso, G. M., Orho-Melander, M., Frikke-Schmidt, R., Barbalic, M., Jensen, M. K., Hindy, G., Hólm, H., Ding, E. L., Johnson, T., et al. (2012) · The Lancet

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 148

Evinacumab in severe hypertriglyceridemia with or without lipoprotein lipase pathway mutations: a phase 2 randomized trial

Rosenson, R. S., Gaudet, D., Ballantyne, C. M., Baum, S. J., Bergeron, J., Kershaw, E. E., Moriarty, P. M., Rubba, P., Whitcomb, D. C., Banerjee, P., et al. (2023) · Nature Medicine

Lipid metabolism and disordersPancreatitis Pathology and Treatment

Cited by 140

Germline Mutations in CIDEB and Protection against Liver Disease

Verweij, N., Haas, M. E., Nielsen, J. B., Sosina, O. A., Kim, M., Akbari, P., De, T., Hindy, G., Bovijn, J., Persaud, T., et al. (2022) · New England Journal of Medicine

Liver Disease Diagnosis and TreatmentGenetic Associations and Epidemiology

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A deep catalogue of protein-coding variation in 983,578 individuals

Sun, K. Y., Bai, X., Chen, S., Bao, S., Zhang, C., Kapoor, M., Backman, J., Joseph, T., Maxwell, E., Mitra, G., et al. (2024) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

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Functional Analysis and Transcriptomic Profiling of iPSC-Derived Macrophages and Their Application in Modeling Mendelian Disease

Zhang, H., Xue, C., Shah, R., Bermingham, K., Hinkle, C. C., Li, W., Rodrigues, A., Tabita-Martinez, J., Millar, J. S., Cuchel, M., et al. (2015) · Circulation Research

Pluripotent Stem Cells ResearchImmune cells in cancer

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SARS-CoV-2 seroprevalence among parturient women in Philadelphia

Flannery, D. D., Gouma, S., Dhudasia, M. B., Mukhopadhyay, S., Pfeifer, M. R., Woodford, E. C., Gerber, J. S., Arevalo, C. P., Bolton, M. J., Weirick, M. E., et al. (2020) · Science Immunology

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Impact on Reproduction

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Finding missed cases of familial hypercholesterolemia in health systems using machine learning

Banda, J. M., Sarraju, A., Abbasi, F., Parizo, J., Pariani, M., Ison, H., Briskin, E., Wand, H., Dubois, S., Jung, K., et al. (2019) · npj Digital Medicine

Machine Learning in HealthcareArtificial Intelligence in Healthcare

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Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study

Yu Chen, H., Dina, C., Small, A. M., Shaffer, C. M., Levinson, R. T., Helgadóttir, A., Capoulade, R., Munter, H. M., Martinsson, A., Cairns, B. J., et al. (2023) · European Heart Journal

Cardiac Valve Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 116

ANGPTL3 Inhibition With Evinacumab Results in Faster Clearance of IDL and LDL apoB in Patients With Homozygous Familial Hypercholesterolemia—Brief Report

Reeskamp, L. F., Millar, J. S., Wu, L., Jansen, H., van Harskamp, D., Schierbeek, H., Gipe, D. A., Rader, D. J., Dallinga-Thie, G. M., Hovingh, G. K., et al. (2021) · Arteriosclerosis, Thrombosis, and Vascular Biology

Lipoproteins and Cardiovascular HealthLipid metabolism and disorders

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Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection

Painter, M. M., Johnston, T. S., Lundgreen, K. A., Santos, J. J. S., Qin, J. S., Goel, R. R., Apostolidis, S. A., Mathew, D., Fulmer, B., Williams, J. C., et al. (2023) · Nature Immunology

SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations

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CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects

Thomas, T., Zhou, H., Karmally, W., Ramakrishnan, R., Holleran, S., Liu, Y., Jumes, P., Wagner, J. A., Hubbard, B., Previs, S. F., et al. (2017) · Arteriosclerosis, Thrombosis, and Vascular Biology

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

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Genetic Regulatory Mechanisms of Smooth Muscle Cells Map to Coronary Artery Disease Risk Loci

Liu, B., Pjanic, M., Wang, T., Nguyen, T., Gloudemans, M., Rao, A., Castano, V. G., Nurnberg, S., Rader, D. J., Elwyn, S., et al. (2018) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

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Insulin resistance and chronic kidney disease progression, cardiovascular events, and death: findings from the chronic renal insufficiency cohort study

Schrauben, S. J., Jepson, C., Hsu, J. Y., Wilson, F. P., Zhang, X., Lash, J. P., Robinson, B. M., Townsend, R. R., Chen, J., Fogelfeld, L., et al. (2019) · BMC Nephrology

Chronic Kidney Disease and DiabetesDiabetes, Cardiovascular Risks, and Lipoproteins

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