Kornhuber, Johannes

Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression

Steinacker, P., Verde, F., Fang, L., Feneberg, E., Oeckl, P., Roeber, S., Anderl-Straub, S., Danek, A., Diehl-Schmid, J., Fassbender, K., et al. (2018) · Journal of Neurology, Neurosurgery & Psychiatry

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

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Amyloidogenic amyloid-β-peptide variants induce microbial agglutination and exert antimicrobial activity

Spitzer, P., Condic, M., Herrmann, M., Oberstein, T. J., Scharin-Mehlmann, M., Gilbert, D. F., Friedrich, O., Grömer, T., Kornhuber, J., Lang, R., et al. (2016) · Scientific Reports

Antimicrobial Peptides and ActivitiesAlzheimer's disease research and treatments

Cited by 128

A combined miRNA-piRNA signature to detect Alzheimer’s disease

Jain, G., Stuendl, A., Rao, P., Berulava, T., Pena Centeno, T., Kaurani, L., Burkhardt, S., Delalle, I., Kornhuber, J., Hüll, M., et al. (2019) · Translational Psychiatry

Extracellular vesicles in diseaseDementia and Cognitive Impairment Research

Cited by 121

Poly‐GP in cerebrospinal fluid links C9orf72‐associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD

Lehmer, C., Oeckl, P., Weishaupt, J. H., Volk, A. E., Diehl‐Schmid, J., Schroeter, M. L., Lauer, M., Kornhuber, J., Levin, J., Fassbender, K., et al. (2017) · EMBO Molecular Medicine

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative Diseases

Cited by 118

Serum neurofilament light chain in behavioral variant frontotemporal dementia

Steinacker, P., Anderl-Straub, S., Diehl-Schmid, J., Semler, E., Uttner, I., von Arnim, C. A. F., Barthel, H., Danek, A., Fassbender, K., Fliessbach, K., et al. (2018) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 116

Cerebrospinal Fluid Biomarkers and Clinical Progression in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment

Wolfsgruber, S., Polcher, A., Koppara, A., Kleineidam, L., Frölich, L., Peters, O., Hüll, M., Rüther, E., Wiltfang, J., Maier, W., et al. (2017) · Journal of Alzheimer's Disease

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 114

LDL cholesterol relates to depression, its severity, and the prospective course

Wagner, C. J., Musenbichler, C., Böhm, L., Färber, K., Fischer, A.-I., von Nippold, F., Winkelmann, M., Richter-Schmidinger, T., Mühle, C., Kornhuber, J., et al. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry

Treatment of Major DepressionTryptophan and brain disorders

Cited by 106

Neurofilament ELISA validation

Petzold, A., Altintas, A., Andreoni, L., Bartos, A., Berthele, A., Blankenstein, M. A., Buee, L., Castellazzi, M., Cepok, S., Comabella, M., et al. (2010) · Journal of Immunological Methods

Clinical Laboratory Practices and Quality ControlReliability and Agreement in Measurement

Cited by 105

Genome-wide significant risk factors for Alzheimer’s disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment

Lacour, A., Espinosa, A., Louwersheimer, E., Heilmann, S., Hernández, I., Wolfsgruber, S., Fernández, V, Wagner, H., Rosende-Roca, M., Mauleón, A., et al. (2017) · Molecular Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 101

Effect of Minocycline on Depressive Symptoms in Patients With Treatment-Resistant Depression: A Randomized Clinical Trial

Hellmann-Regen, J., Clemens, V., Grözinger, M., Kornhuber, J., Reif, A., Prvulovic, D., Goya-Maldonado, R., Wiltfang, J., Gruber, O., Schüle, C., et al. (2022) · JAMA Network Open

Treatment of Major DepressionTryptophan and brain disorders

Cited by 100

TNF-α and IL-6 serum levels: neurobiological markers of alcohol consumption in alcohol-dependent patients?

Heberlein, A., Käser, M., Lichtinghagen, R., Rhein, M., Lenz, B., Kornhuber, J., Bleich, S., & Hillemacher, T. (2014) · Alcohol

Alcohol Consumption and Health EffectsSubstance Abuse Treatment and Outcomes

Cited by 98

Cellular Receptors of Amyloid β Oligomers (AβOs) in Alzheimer’s Disease

Mroczko, B., Groblewska, M., Litman-Zawadzka, A., Kornhuber, J., & Lewczuk, P. (2018) · International Journal of Molecular Sciences

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 97

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

Mattsson, N., Groot, C., Jansen, W. J., Landau, S. M., Villemagne, V. L., Engelborghs, S., Mintun, M. M., Lleo, A., Molinuevo, J. L., Jagust, W. J., et al. (2018) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 88

Plasma neurofilament light and phosphorylated tau 181 as biomarkers of Alzheimer’s disease pathology and clinical disease progression

Clark, C., Lewczuk, P., Kornhuber, J., Richiardi, J., Maréchal, B., Karikari, T. K., Blennow, K., Zetterberg, H., & Popp, J. (2021) · Alzheimer's Research & Therapy

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

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Predicting behavioral variant frontotemporal dementia with pattern classification in multi-center structural MRI data

Meyer, S., Mueller, K., Stuke, K., Bisenius, S., Diehl-Schmid, J., Jessen, F., Kassubek, J., Kornhuber, J., Ludolph, A. C., Prudlo, J., et al. (2017) · NeuroImage: Clinical

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

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Microstructural abnormalities of the posterior thalamic radiation and the mediodorsal thalamic nuclei in females with anorexia nervosa–a voxel based diffusion tensor imaging (DTI) study

Frieling, H., Fischer, J., Wilhelm, J., Engelhorn, T., Bleich, S., Hillemacher, T., Dörfler, A., Kornhuber, J., de Zwaan, M., & Peschel, T. (2012) · Journal of Psychiatric Research

Eating Disorders and BehaviorsAdvanced Neuroimaging Techniques and Applications

Cited by 79

BDNF serum levels and promoter methylation of BDNF exon I, IV and VI in depressed patients receiving electroconvulsive therapy

Kleimann, A., Kotsiari, A., Sperling, W., Gröschl, M., Heberlein, A., Kahl, K. G., Hillemacher, T., Bleich, S., Kornhuber, J., & Frieling, H. (2015) · Journal of Neural Transmission

Electroconvulsive Therapy StudiesTreatment of Major Depression

Cited by 70

Cortical activity associated with auditory hallucinations

Ropohl, A., Sperling, W., Elstner, S., Tomandl, B., Reulbach, U., Kaltenhäuser, M., Kornhuber, J., & Maihöfner, C. (2004) · NeuroReport

Hallucinations in medical conditionsSchizophrenia research and treatment

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PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment

(ADNI), A. D. N. I., Kleineidam, L., Chouraki, V., Próchnicki, T., van der Lee, S. J., Madrid-Márquez, L., Wagner-Thelen, H., Karaca, I., Weinhold, L., Wolfsgruber, S., et al. (2020) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Genome-wide association study of vascular dementia

Schrijvers, E. M. C., Schürmann, B., Koudstaal, P. J., van den Bussche, H., Van Duijn, C. M., Hentschel, F., Heun, R., Hofman, A., Jessen, F., Kölsch, H., et al. (2012) · Stroke

Dementia and Cognitive Impairment ResearchGenetic Associations and Epidemiology

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Sphingolipids in Psychiatric Disorders and Pain Syndromes

Mühle, C., Reichel, M., Gulbins, E., & Kornhuber, J. (2013) · Handbook of Experimental Pharmacology

Sphingolipid Metabolism and SignalingLysosomal Storage Disorders Research

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Predicting primary progressive aphasias with support vector machine approaches in structural MRI data

Bisenius, S., Mueller, K., Diehl-Schmid, J., Fassbender, K., Grimmer, T., Jessen, F., Kassubek, J., Kornhuber, J., Landwehrmeyer, B., Ludolph, A., et al. (2017) · NeuroImage: Clinical

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

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SUCLG2 identified as both a determinator of CSF Aβ1–42 levels and an attenuator of cognitive decline in Alzheimer's disease

Ramirez, A., van der Flier, W. M., Herold, C., Ramonet, D., Heilmann, S., Lewczuk, P., Popp, J., Lacour, A., Drichel, D., Louwersheimer, E., et al. (2014) · Human Molecular Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Potential genetic markers of sporadic Alzheimerʼs dementia

Retz, W., Thome, J., Durany, N., Harsányi, A., Retz-Junginger, P., Kornhuber, J., Riederer, P., & Rösler, M. (2001) · Psychiatric Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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