Freedman, Robert

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 2,964

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Lee, P. H., Anttila, V., Won, H., Feng, Y.-C. A., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., et al. (2019) · Cell

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 1,381

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Genovese, G., Loh, P.-R., Bhatia, G., Do, R., et al. (2015) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,303

Preventive strategies for mental health

Arango, C., Díaz-Caneja, C. M., McGorry, P. D., Rapoport, J., Sommer, I. E., Vorstman, J. A., McDaid, D., Marín, O., Serrano-Drozdowskyj, E., Freedman, R., et al. (2018) · The Lancet Psychiatry

Mental Health Treatment and AccessChild and Adolescent Psychosocial and Emotional Development

Cited by 1,271

Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

Freedman, R., Coon, H., Myles-Worsley, M., Orr-Urtreger, A., Olincy, A., Davis, A., Polymeropoulos, M., Holik, J., Hopkins, J., Hoff, M., et al. (1997) · Proceedings of the National Academy of Sciences

Schizophrenia research and treatmentNicotinic Acetylcholine Receptors Study

Cited by 1,141

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Marshall, C. R., Howrigan, D. P., Merico, D., Thiruvahindrapuram, B., Wu, W., Greer, D. S., Antaki, D., Shetty, A., Holmans, P. A., Pinto, D., et al. (2017) · Nature Genetics

Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment

Cited by 1,058

Schizophrenia, sensory gating, and nicotinic receptors

Adler, L. E., Olincy, A., Waldo, M., Harris, J. G., Griffith, J., Stevens, K., Flach, K., Nagamoto, H., Bickford, P., Leonard, S., et al. (1998) · Schizophrenia Bulletin

Nicotinic Acetylcholine Receptors StudySchizophrenia research and treatment

Cited by 690

Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia

Freedman, R., Hall, M., Adler, L. E., & Leonard, S. (1995) · Biological Psychiatry

Nicotinic Acetylcholine Receptors StudySchizophrenia research and treatment

Cited by 678

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

Gusev, A., Lee, S. H., Trynka, G., Finucane, H., Vilhjálmsson, B. J., Xu, H., Zang, C., Ripke, S., Bulik-Sullivan, B., Stahl, E., et al. (2014) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 544

Spatial and Temporal Mapping of De Novo Mutations in Schizophrenia to a Fetal Prefrontal Cortical Network

Gulsuner, S., Walsh, T., Watts, A. C., Lee, M. K., Thornton, A. M., Casadei, S., Rippey, C., Shahin, H., Braff, D., Cadenhead, K. S., et al. (2013) · Cell

Schizophrenia research and treatmentGenomic variations and chromosomal abnormalities

Cited by 536

Effects of putative neurotransmitters on neuronal activity in monkey auditory cortex

Foote, S. L., Freedman, R., & Oliver, A. P. (1975) · Brain Research

Neuroscience and Music PerceptionNeuroscience and Neuropharmacology Research

Cited by 458

Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications

Levinson, D. F., Duan, J., Oh, S., Wang, K., Sanders, A. R., Shi, J., Zhang, N., Mowry, B. J., Olincy, A., Amin, F., et al. (2011) · American Journal of Psychiatry

Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment

Cited by 434

Neurobiological studies of sensory gating in schizophrenia

Freedman, R., Adler, L. E., Gerhardt, G. A., Waldo, M., Baker, N., Rose, G. M., Drebing, C., Nagamoto, H., Bickford-Wimer, P., & Franks, R. (1987) · Schizophrenia Bulletin

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 430

Initial phase 2 trial of a nicotinic agonist in schizophrenia

Freedman, R., Olincy, A., Buchanan, R. W., Harris, J. G., Gold, J. M., Johnson, L., Allensworth, D., Guzman-Bonilla, A., Clement, B., Ball, M. P., et al. (2008) · American Journal of Psychiatry

Nicotinic Acetylcholine Receptors StudySchizophrenia research and treatment

Cited by 426

Sensory Processing Dysfunction in the Personal Experience and Neuronal Machinery of Schizophrenia

Javitt, D. C., & Freedman, R. (2015) · American Journal of Psychiatry

Schizophrenia research and treatmentMental Health and Psychiatry

Cited by 403

Acetylcholine Activates an α-Bungarotoxin-Sensitive Nicotinic Current in Rat Hippocampal Interneurons, But Not Pyramidal Cells

Frazier, C. J., Rollins, Y. D., Breese, C. R., Leonard, S., Freedman, R., & Dunwiddie, T. V. (1998) · The Journal of Neuroscience

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

Cited by 374

No Significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics

Sanders, A. R., Duan, J., Levinson, D. F., Shi, J., He, D., Hou, C., Burrell, G. J., Rice, J. P., Nertney, D. A., Olincy, A., et al. (2008) · American Journal of Psychiatry

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 349

The Initial Field Trials of DSM-5: New Blooms and Old Thorns

Freedman, R., Lewis, D. A., Michels, R., Pine, D. S., Schultz, S. K., Tamminga, C. A., Gabbard, G. O., Gau, S. S.-F., Javitt, D. C., Oquendo, M. A., et al. (2013) · American Journal of Psychiatry

Personality Disorders and PsychopathologyMental Health Research Topics

Cited by 295

Analysis of 94 Candidate Genes and 12 Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia

Greenwood, T. A., Lazzeroni, L. C., Murray, S. S., Cadenhead, K. S., Calkins, M. E., Dobie, D. J., Green, M. F., Gur, R. E., Gur, R. C., Hardiman, G., et al. (2011) · American Journal of Psychiatry

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 257

Schizophrenia and the α7 Nicotinic Acetylcholine Receptor

Martin, L. F., & Freedman, R. (2007) · International Review of Neurobiology

Nicotinic Acetylcholine Receptors StudySchizophrenia research and treatment

Cited by 213

Neurophysiological and neuropsychological evidence for attentional dysfunction in schizophrenia

Cullum, C. M., Harris, J. G., Waldo, M. C., Smernoff, E., Madison, A., Nagamoto, H. T., Griffith, J., Adler, L. E., & Freedman, R. (1993) · Schizophrenia Research

Schizophrenia research and treatmentNeural and Behavioral Psychology Studies

Cited by 212

Neural Systems Governed by Nicotinic Acetylcholine Receptors: Emerging Hypotheses

Miwa, J. M., Freedman, R., & Lester, H. A. (2011) · Neuron

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

Cited by 205

Smoking and schizophrenia: abnormal nicotinic receptor expression

Leonard, S., Breese, C., Adams, C., Benhammou, K., Gault, J., Stevens, K., Lee, M., Adler, L., Olincy, A., Ross, R., et al. (2000) · European Journal of Pharmacology

Nicotinic Acetylcholine Receptors StudySchizophrenia research and treatment

Cited by 177

Perinatal Choline Effects on Neonatal Pathophysiology Related to Later Schizophrenia Risk

Ross, R. G., Hunter, S. K., McCarthy, L., Beuler, J., Hutchison, A. K., Wagner, B. D., Leonard, S., Stevens, K. E., & Freedman, R. (2013) · American Journal of Psychiatry

Schizophrenia research and treatmentNicotinic Acetylcholine Receptors Study

Cited by 165