Replicative and chronological aging in Saccharomyces cerevisiae

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

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Extending Healthy Life Span—From Yeast to Humans

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The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

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Requirement of NAD and <i>SIR2</i> for Life-Span Extension by Calorie Restriction in <i>Saccharomyces cerevisiae</i>

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Induction of autophagy by spermidine promotes longevity

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Extrachromosomal rDNA circles—a cause of aging in yeast

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Recent progress in the biology and physiology of sirtuins

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Regulation of Yeast Replicative Life Span by TOR and Sch9 in Response to Nutrients

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Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

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Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration

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Extension of Chronological Life Span in Yeast by Decreased TOR Pathway Signaling

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Regulation of Longevity and Stress Resistance by Sch9 in Yeast

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A Yeast Mutant Showing Diagnostic Markers of Early and Late Apoptosis

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How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)

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Life Span of Individual Yeast Cells

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Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activityPreprint

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Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans

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The daf‐2 gene network for longevity regulates oxidative stress resistance and Mn‐superoxide dismutase gene expression in Caenorhabditis elegans

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Histone H4 lysine 16 acetylation regulates cellular lifespan

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The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in <i>C. elegans</i>

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Asymmetric Inheritance of Oxidatively Damaged Proteins During Cytokinesis

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A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans

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Sirtuins in aging and age-related disease

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Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

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Chronological aging leads to apoptosis in yeast

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Aging as an event of proteostasis collapse

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Superoxide Dismutase Activity Is Essential for Stationary Phase Survival in Saccharomyces cerevisiae

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The chronological life span of Saccharomyces cerevisiae

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FLP Recombinase-Mediated Induction of Cu/Zn-Superoxide Dismutase Transgene Expression Can Extend the Life Span of Adult Drosophila melanogaster Flies

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Yeast Life Span Extension by Depletion of 60S Ribosomal Subunits Is Mediated by Gcn4

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Life Span Extension by Calorie Restriction Depends on Rim15 and Transcription Factors Downstream of Ras/PKA, Tor, and Sch9

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Elevated histone expression promotes life span extension

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Reduced TOR Signaling Extends Chronological Life Span via Increased Respiration and Upregulation of Mitochondrial Gene Expression

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Lessons on longevity from budding yeast

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Sir2 Blocks Extreme Life-Span Extension

Fabrizio, P., Gattazzo, C., Battistella, L., Wei, M., Cheng, C., McGrew, K., & Longo, V. D. (2005) · Cell · doi:10.1016/j.cell.2005.08.042 · Cited by 390 · see citing works

An intervention resembling caloric restriction prolongs life span and retards aging in yeast

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Induced Overexpression of Mitochondrial Mn-Superoxide Dismutase Extends the Life Span of Adult Drosophila melanogaster

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Accelerated aging and failure to segregate damaged proteins in Sir2 mutants can be suppressed by overproducing the protein aggregation-remodeling factor Hsp104pPreprint

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Superoxide is a mediator of an altruistic aging program in <i>Saccharomyces cerevisiae</i>

Fabrizio, P., Battistella, L., Vardavas, R., Gattazzo, C., Liou, L.-L., Diaspro, A., Dossen, J. W., Gralla, E. B., & Longo, V. D. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200404002 · Cited by 355 · see citing works

Type 5 Adenylyl Cyclase Disruption Increases Longevity and Protects Against Stress

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A molecular mechanism of chronological aging in yeast

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Lifespan extension in Caenorhabditis elegans by complete removal of food

Kaeberlein, T. L., Smith, E. D., Tsuchiya, M., Welton, K. L., Thomas, J. H., Fields, S., Kennedy, B. K., & Kaeberlein, M. R. (2006) · Aging Cell · doi:10.1111/j.1474-9726.2006.00238.x · Cited by 336 · see citing works

SOD2 Functions Downstream of Sch9 to Extend Longevity in Yeast

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Endonuclease G Regulates Budding Yeast Life and Death

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Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae

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Regulation of Yeast Chronological Life Span by TORC1 via Adaptive Mitochondrial ROS Signaling

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TOR and PKA Signaling Pathways Converge on the Protein Kinase Rim15 to Control Entry into G0

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MSN2 and MSN4 Link Calorie Restriction and TOR to Sirtuin-Mediated Lifespan Extension in Saccharomyces cerevisiae

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Protein Acetylation Microarray Reveals that NuA4 Controls Key Metabolic Target Regulating Gluconeogenesis

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Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae

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Dietary deprivation extends lifespan in <i>Caenorhabditis elegans</i>

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Involvement of distinct G‐proteins, Gpa2 and Ras, in glucose‐ and intracellular acidification‐induced cAMP signalling in the yeast Saccharomyces cerevisiae

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A Stress-Responsive System for Mitochondrial Protein Degradation

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Acute glucose starvation activates the nuclear localization signal of a stress‐specific yeast transcription factor

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Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H 2 O 2 and superoxide dismutase activity

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Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae

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Dietary Restriction and Aging

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Stationary phase in Saccharomyces cerevisiae

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Simultaneous Overexpression of Copper- and Zinc-containing Superoxide Dismutase and Catalase Retards Age-related Oxidative Damage and Increases Metabolic Potential in Drosophila melanogaster

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Protein Kinase A and Sch9 Cooperatively Regulate Induction of Autophagy inSaccharomyces cerevisiae

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The Chronological Life Span of Saccharomyces cerevisiae

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The essence of yeast quiescence

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Autophagy and amino acid homeostasis are required for chronological longevity in Saccharomyces cerevisiae

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HST2 Mediates SIR2 -Independent Life-Span Extension by Calorie Restriction

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The TOR signalling network from yeast to man

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Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins

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Saccharomyces cerevisiae cAMP-dependent protein kinase controls entry into stationary phase through the Rim15p protein kinasePreprint

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Mitochondrial Superoxide Decreases Yeast Survival in Stationary Phase

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Saccharomyces cerevisiae Ras/cAMP pathway controls post‐diauxic shift element‐dependent transcription through the zinc finger protein Gis1

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Life in the midst of scarcity: adaptations to nutrient availability in Saccharomyces cerevisiae

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Quantitative evidence for conserved longevity pathways between divergent eukaryotic speciesPreprint

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The Mother Enrichment Program: A Genetic System for Facile Replicative Life Span Analysis in Saccharomyces cerevisiae

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Tor1/Sch9-Regulated Carbon Source Substitution Is as Effective as Calorie Restriction in Life Span Extension

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Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes

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Chronological aging‐independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae

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Increased Life Span due to Calorie Restriction in Respiratory-Deficient Yeast

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Genome-Wide Screen in Saccharomyces cerevisiae Identifies Vacuolar Protein Sorting, Autophagy, Biosynthetic, and tRNA Methylation Genes Involved in Life Span Regulation

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The Novel Yeast PAS Kinase Rim15 Orchestrates G0-Associated Antioxidant Defense Mechanisms

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Effects of Cu-Zn Superoxide Dismutase Overexpression on Life Span and Resistance to Oxidative Stress in Transgenic Drosophila melanogaster

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Measuring Replicative Life Span in the Budding Yeast

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Gametogenesis Eliminates Age-Induced Cellular Damage and Resets Life Span in Yeast

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Acetylation of Yeast AMPK Controls Intrinsic Aging Independently of Caloric Restriction

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Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density

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Increased transsulfuration mediates longevity and dietary restriction in Drosophila

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The caloric restriction paradigm: Implications for healthy human aging

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Defective Mitochondrial Gene Expression Results in Reactive Oxygen Species-Mediated Inhibition of Respiration and Reduction of Yeast Life Span

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A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis

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Effect of calorie restriction on the metabolic history of chronologically aging yeast

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