Patterson, Andrew D.

Bile acids and the gut microbiota: metabolic interactions and impacts on disease

Collins, S. L., Stine, J. G., Bisanz, J. E., Okafor, C. D., & Patterson, A. D. (2023) · Nature Reviews Microbiology

Gut microbiota and healthDrug Transport and Resistance Mechanisms

Cited by 1,214

Gut microbiota and intestinal FXR mediate the clinical benefits of metformin

Sun, L., Xie, C., Wang, G., Wu, Y., Wu, Q., Wang, X., Liu, J., Deng, Y., Xia, J., Chen, B., et al. (2018) · Nature Medicine

Gut microbiota and healthMetabolism, Diabetes, and Cancer

Cited by 1,011

Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity

Li, F., Jiang, C., Krausz, K. W., Li, Y., Albert, I., Hao, H., Fabre, K. M., Mitchell, J. B., Patterson, A. D., & Gonzalez, F. J. (2013) · Nature Communications

Gut microbiota and healthDrug Transport and Resistance Mechanisms

Cited by 705

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

Jiang, C., Xie, C., Li, F., Zhang, L., Nichols, R. G., Krausz, K. W., Cai, J., Qi, Y., Fang, Z.-Z., Takahashi, S., et al. (2015) · Journal of Clinical Investigation

Liver Disease Diagnosis and TreatmentGut microbiota and health

Cited by 693

Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota

Li, G., Xie, C., Lu, S., Nichols, R. G., Tian, Y., Li, L., Patel, D., Ma, Y., Brocker, C. N., Yan, T., et al. (2017) · Cell Metabolism

Adipose Tissue and MetabolismDietary Effects on Health

Cited by 667

Intestine farnesoid X receptor agonist and the gut microbiota activate G‐protein bile acid receptor‐1 signaling to improve metabolism

Pathak, P., Xie, C., Nichols, R. G., Ferrell, J. M., Boehme, S., Krausz, K. W., Patterson, A. D., Gonzalez, F. J., & Chiang, J. Y. L. (2018) · Hepatology

Drug Transport and Resistance MechanismsGut microbiota and health

Cited by 567

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

Jiang, C., Xie, C., Lv, Y., Li, J., Krausz, K. W., Shi, J., Brocker, C. N., Desai, D., Amin, S. G., Bisson, W. H., et al. (2015) · Nature Communications

Drug Transport and Resistance MechanismsCholesterol and Lipid Metabolism

Cited by 559

Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

Singh, V., Yeoh, B. S., Chassaing, B., Xiao, X., Saha, P., Aguilera Olvera, R., Lapek, J. D., Zhang, L., Wang, W.-B., Hao, S., et al. (2018) · Cell

Gut microbiota and healthMicrobial Metabolites in Food Biotechnology

Cited by 532

Profiling the human intestinal environment under physiological conditions

Shalon, D., Culver, R. N., Grembi, J. A., Folz, J., Treit, P. V., Shi, H., Rosenberger, F. A., Dethlefsen, L., Meng, X., Yaffe, E., et al. (2023) · Nature

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 484

Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles

Hubbard, T. D., Murray, I. A., Bisson, W. H., Lahoti, T. S., Gowda, K., Amin, S. G., Patterson, A. D., & Perdew, G. H. (2015) · Scientific Reports

Gut microbiota and healthToxic Organic Pollutants Impact

Cited by 377

The gut microbiome: an orchestrator of xenobiotic metabolism

Collins, S. L., & Patterson, A. D. (2020) · Acta Pharmaceutica Sinica B

Pharmacogenetics and Drug MetabolismGut microbiota and health

Cited by 348

Randomized Controlled-Feeding Study of Dietary Emulsifier Carboxymethylcellulose Reveals Detrimental Impacts on the Gut Microbiota and Metabolome

Chassaing, B., Compher, C., Bonhomme, B., Liu, Q., Tian, Y., Walters, W., Nessel, L., Delaroque, C., Hao, F., Gershuni, V., et al. (2022) · Gastroenterology

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 347

Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis

Das, N. K., Schwartz, A. J., Barthel, G., Inohara, N., Liu, Q., Sankar, A., Hill, D. R., Ma, X., Lamberg, O., Schnizlein, M. K., et al. (2020) · Cell Metabolism

Iron Metabolism and DisordersGut microbiota and health

Cited by 331

Bile Acids Are Substrates for Amine N-Acyl Transferase Activity by Bile Salt Hydrolase

Patterson, A., Rimal, B., Collins, S., Granda, M., Koo, I., Solanka, S., Hoque, N., Gentry, E., Yan, T., Bisanz, J., et al. (2022) · Nature

Gut microbiota and healthDrug Transport and Resistance Mechanisms

Cited by 252

A Synthesis-Based Reverse Metabolomics Approach for the Discovery of Chemical Structures from Humans and Animals.

Dorrestein, P., Gentry, E., Collins, S., Panitchpakdi, M., Belda-Ferre, P., Stewart, A., Wang, M., Jarmusch, A., Avila-Pacheco, J., Plichta, D., et al. (2021) · Nature

Metabolomics and Mass Spectrometry StudiesGut microbiota and health

Cited by 197

Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota

Li, G., Xie, C., Lu, S., Nichols, R. G., Tian, Y., Li, L., Patel, D., Ma, Y., Brocker, C. N., Yan, T., et al. (2017) · Cell Metabolism

Gut microbiota and healthDietary Effects on Health

Cited by 144

Impaired Intestinal Akkermansia muciniphila and Aryl Hydrocarbon Receptor Ligands Contribute to Nonalcoholic Fatty Liver Disease in Mice

Shi, Z., Lei, H., Chen, G., Yuan, P., Cao, Z., Ser, H.-L., Zhu, X., Wu, F., Liu, C., Dong, M., et al. (2021) · mSystems

Gut microbiota and healthLiver Disease Diagnosis and Treatment

Cited by 71

Novel metabolites and roles for α-tocopherol in humans and mice discovered by mass spectrometry–based metabolomics

Johnson, C. H., Slanař, O., Krausz, K. W., Kang, D. W., Patterson, A. D., Kim, J.-H., Luecke, H., Gonzalez, F. J., & Idle, J. R. (2012) · The American Journal of Clinical Nutrition

Antioxidant Activity and Oxidative StressMetabolomics and Mass Spectrometry Studies

Cited by 58

Stable Isotope- and Mass Spectrometry-based Metabolomics as Tools in Drug Metabolism: A Study Expanding Tempol Pharmacology

Li, F., Pang, X., Krausz, K. W., Jiang, C., Chen, C., Cook, J. A., Krishna, M. C., Mitchell, J. B., Gonzalez, F. J., & Patterson, A. D. (2013) · Journal of Proteome Research

Metabolomics and Mass Spectrometry StudiesPharmacogenetics and Drug Metabolism

Cited by 31

In vitro microbiota model recapitulates and predicts individualised sensitivity to dietary emulsifier

Rytter, H., Naimi, S., Wu, G., Lewis, J., Duquesnoy, M., Vigué, L., Tenaillon, O., Belda, E., Vazquez-Gomez, M., Touly, N., et al. (2025) · Gut

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 19

Nonalcoholic steatohepatitis Fitness Intervention in Thrombosis (NASHFit): Study protocol for a randomized controlled trial of a supervised aerobic exercise program to reduce elevated clotting risk in patients with NASH

Stine, J. G., Schreibman, I., Navabi, S., Kang, M., Dahmus, J., Soriano, C., Rivas, G., Hummer, B., Beyer, M., Tressler, H., et al. (2020) · Contemporary Clinical Trials Communications

Liver Disease Diagnosis and TreatmentPhysical Activity and Health

Cited by 19

Modulation of urinary siderophores by the diet, gut microbiota and inflammation in mice

Xiao, X., Yeoh, B. S., Saha, P., Tian, Y., Singh, V., Patterson, A. D., & Vijay-Kumar, M. (2017) · The Journal of Nutritional Biochemistry

Iron Metabolism and DisordersTrace Elements in Health

Cited by 16

Human Intestinal Microbiome Determines Individualized Inflammatory Response to Dietary Emulsifier Carboxymethylcellulose Consumption

Daniel, N., Wu, G. D., Walters, W., Compher, C., Ni, J., Delaroque, C., Albenberg, L., Ley, R. E., Patterson, A. D., Lewis, J. D., et al. (2024) · Cellular and Molecular Gastroenterology and Hepatology

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 14