Therapy for Fibrotic Diseases: Nearing the Starting Line

Exploring the full spectrum of macrophage activation

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An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

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Alternative activation of macrophages

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Cellular and molecular mechanisms of fibrosis

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The unfolded protein response: controlling cell fate decisions under ER stress and beyond

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Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

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Mechanisms of fibrosis: therapeutic translation for fibrotic disease

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Mechanisms of Hepatic Fibrogenesis

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Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

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TRANSFORMING GROWTH FACTOR-β REGULATION OF IMMUNE RESPONSES

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A Mechanism for Regulating Pulmonary Inflammation and Fibrosis: The Integrin αvβ6 Binds and Activates Latent TGF β1

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Endothelial/Pericyte Interactions

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Evidence that fibroblasts derive from epithelium during tissue fibrosis

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Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

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Evidence that fibroblasts derive from epithelium during tissue fibrosis

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Lebrikizumab Treatment in Adults with Asthma

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Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases

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Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

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Macrophages: master regulators of inflammation and fibrosis

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Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix

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Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

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TGFβ: the molecular Jekyll and Hyde of cancer

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Macrophage Polarization Comes of Age

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Alveolar epithelial cell mesenchymal transition develops <i>in vivo</i> during pulmonary fibrosis and is regulated by the extracellular matrix

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Endoplasmic reticulum stress in liver disease

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Efficacy of a Tyrosine Kinase Inhibitor in Idiopathic Pulmonary Fibrosis

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Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

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Latent TGF-β structure and activation

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Long-Term Entecavir Therapy Results in the Reversal of Fibrosis/Cirrhosis and Continued Histological Improvement in Patients with Chronic Hepatitis B†,‡

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EMT: When epithelial cells decide to become mesenchymal-like cells

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Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition

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Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

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A Pericyte Origin of Spinal Cord Scar Tissue

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NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

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Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

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The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling

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Fibroblasts Derive from Hepatocytes in Liver Fibrosis via Epithelial to Mesenchymal Transition

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Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney

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The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak

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Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis

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Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

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NAD(P)H Oxidase 4 Mediates Transforming Growth Factor-β1–Induced Differentiation of Cardiac Fibroblasts Into Myofibroblasts

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Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis

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Regulation of PDGF and its receptors in fibrotic diseases

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MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways

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