Jahn, Reinhard

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 2,964

SNAREs — engines for membrane fusion

Jahn, R., & Scheller, R. H. (2006) · Nature Reviews Molecular Cell Biology

Cellular transport and secretionLipid Membrane Structure and Behavior

Cited by 2,635

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution

Sutton, R. B., Fasshauer, D., Jahn, R., & Brunger, A. T. (1998) · Nature

Cellular transport and secretionLipid Membrane Structure and Behavior

Cited by 2,417

Molecular anatomy of a trafficking organelle

Takamori, S., Holt, M., Stenius, K., Lemke, E. A., Grønborg, M., Riedel, D., Urlaub, H., Schenck, S., Brügger, B., Ringler, P., et al. (2006) · Cell

Cellular transport and secretionExtracellular vesicles in disease

Cited by 2,373

Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface

Brose, N., Petrenko, A. G., Südhof, T. C., & Jahn, R. (1992) · Science

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 979

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

Koopmans, F., van Nierop, P., Andres-Alonso, M., Byrnes, A., Cijsouw, T., Coba, M. P., Cornelisse, L. N., Farrell, R. J., Goldschmidt, H. L., Howrigan, D. P., et al. (2019) · Neuron

Biomedical Text Mining and OntologiesBioinformatics and Genomic Networks

Cited by 938

Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons

Takamori, S., Rhee, J. S., Rosenmund, C., & Jahn, R. (2000) · Nature

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 862

Membrane protein sequestering by ionic protein–lipid interactions

van den Bogaart, G., Meyenberg, K., Risselada, H. J., Amin, H., Willig, K. I., Hubrich, B. E., Dier, M., Hell, S. W., Grubmüller, H., Diederichsen, U., et al. (2011) · Nature

Cellular transport and secretionLipid Membrane Structure and Behavior

Cited by 617

Structural Changes Are Associated with Soluble N-Ethylmaleimide-sensitive Fusion Protein Attachment Protein Receptor Complex Formation

Fasshauer, D., Otto, H., Eliason, W. K., Jahn, R., & Brünger, A. T. (1997) · Journal of Biological Chemistry

Cellular transport and secretionLipid Membrane Structure and Behavior

Cited by 378

SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils.

Chapman, E. R., An, S., Barton, N., & Jahn, R. (1994) · Journal of Biological Chemistry

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 295

Single-molecule fluorescence resonance energy transfer reveals a dynamic equilibrium between closed and open conformations of syntaxin 1

Margittai, M., Widengren, J., Schweinberger, E., Schröder, G. F., Felekyan, S., Haustein, E., König, M., Fasshauer, D., Grubmüller, H., Jahn, R., et al. (2003) · Proceedings of the National Academy of Sciences

Cellular transport and secretionAdvanced Fluorescence Microscopy Techniques

Cited by 290

CASK Functions as a Mg2+-independent neurexin kinase

Mukherjee, K., Sharma, M., Urlaub, H., Bourenkov, G. P., Jahn, R., Südhof, T. C., & Wahl, M. C. (2008) · Cell

Protein Kinase Regulation and GTPase SignalingNeuroscience and Neuropharmacology Research

Cited by 271

Mechanisms of SNARE proteins in membrane fusion

Jahn, R., Cafiso, D. C., & Tamm, L. K. (2024) · Nature Reviews Molecular Cell Biology

Cellular transport and secretionLipid Membrane Structure and Behavior

Cited by 248

The R-SNARE Endobrevin/VAMP-8 Mediates Homotypic Fusion of Early Endosomes and Late Endosomes

Antonin, W., Holroyd, C., Tikkanen, R., Höning, S., & Jahn, R. (2000) · Molecular Biology of the Cell

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 156

Single-vesicle imaging reveals different transport mechanisms between glutamatergic and GABAergic vesicles

Farsi, Z., Preobraschenski, J., van den Bogaart, G., Riedel, D., Jahn, R., & Woehler, A. (2016) · Science

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 96

Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3

Upmanyu, N., Jin, J., Emde, H. V. D., Ganzella, M., Bösche, L., Malviya, V. N., Zhuleku, E., Politi, A. Z., Ninov, M., Silbern, I., et al. (2022) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 69

Intrinsic Disorder of the Neuronal SNARE Protein SNAP25a in its Pre-fusion Conformation

Stief, T., Gremer, L., Pribicevic, S., Espinueva, D. F., Vormann, K., Biehl, R., Jahn, R., Pérez-Lara, Á., & Lakomek, N.-A. (2023) · Journal of Molecular Biology

Cellular transport and secretionProtein Structure and Dynamics

Cited by 6