SNAREs — engines for membrane fusion

SNAP receptors implicated in vesicle targeting and fusion

Söllner, T. H., Whiteheart, S. W., Brunner, M., Erdjument‐Bromage, H., Geromanos, S. J., Tempst, P., & Rothman, J. E. (1993) · Nature · doi:10.1038/362318a0 · Cited by 3,239 · see citing works

THE SYNAPTIC VESICLE CYCLE

Südhof, T. C. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131412 · Cited by 2,491 · see citing works

SNAREpins: Minimal Machinery for Membrane Fusion

Weber, T., Zemelman, B. V., McNew, J. A., Westermann, B., Gmachl, M., Parlati, F., Söllner, T. H., & Rothman, J. E. (1998) · Cell · doi:10.1016/s0092-8674(00)81404-x · Cited by 2,481 · see citing works

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution

Sutton, R. B., Fasshauer, D., Jahn, R., & Brunger, A. T. (1998) · Nature · doi:10.1038/26412 · Cited by 2,417 · see citing works

Membrane Fusion

Wilschut, J. (1990) · Cited by 2,414 · see citing works

A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion.

Söllner, T. H., Bennett, M., Whiteheart, S., Scheller, R., & Rothman, J. (1993) · Cell · doi:10.1016/0092-8674(93)90376-2 · Cited by 1,922 · see citing works

The Mechanisms of Vesicle Budding and Fusion

Bonifacino, J. S., & Glick, B. S. (2004) · Cell · doi:10.1016/s0092-8674(03)01079-1 · Cited by 1,863 · see citing works

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

Novick, P., Field, C., & Schekman, R. W. (1980) · Cell · doi:10.1016/0092-8674(80)90128-2 · Cited by 1,807 · see citing works

Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin

Schiavo, G., Benfenati, F., Poulain, B., Rossetto, O., de Laureto, P. P., DasGupta, B. R., & Montecucco, C. (1992) · Nature · doi:10.1038/359832a0 · Cited by 1,803 · see citing works

Membrane fusion.

Jahn, R., & Grubmüller, H. (2002) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(02)00356-3 · Cited by 1,533 · see citing works

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

Bennett, M. K., Calakos, N., & Scheller, R. H. (1992) · Science · doi:10.1126/science.1321498 · Cited by 1,263 · see citing works

AAA+ proteins: have engine, will work

Hanson, P., & Whiteheart, S. (2005) · Nature reviews. Molecular cell biology · doi:10.1038/nrm1684 · Cited by 1,237 · see citing works

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

Blasi, J., Chapman, E. R., Link, E., Binz, T., Yamasaki, S., Camilli, P. V. D., Südhof, T. C., Niemann, H., & Jahn, R. (1993) · Nature · doi:10.1038/365160a0 · Cited by 1,221 · see citing works

Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs

Fasshauer, D., Sutton, R. B., Brünger, A. T., & Jahn, R. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.26.15781 · Cited by 1,055 · see citing works

Structure and Conformational Changes in NSF and Its Membrane Receptor Complexes Visualized by Quick-Freeze/Deep-Etch Electron Microscopy

Hanson, P. I., Roth, R. A., Morisaki, H., Jahn, R., & Heuser, J. E. (1997) · Cell · doi:10.1016/s0092-8674(00)80512-7 · Cited by 797 · see citing works

Protein-lipid interplay in fusion and fission of biological membranes.

Chernomordik, L., & Kozlov, M. (2003) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161504 · Cited by 793 · see citing works

Three-dimensional structure of the neuronal-Sec1–syntaxin 1a complex

Misura, K. M. S., Scheller, R. H., & Weis, W. I. (2000) · Nature · doi:10.1038/35006120 · Cited by 786 · see citing works

A conformational switch in syntaxin during exocytosis: role of munc18

Dulubova, I., Sugita, S., Hill, S., Hosaka, M., Fernández, I., Südhof, T., & Rizo, J. (1999) · EMBO Journal · doi:10.1093/emboj/18.16.4372 · Cited by 772 · see citing works

A genomic perspective on membrane compartment organization

Bock, J. B., Matern, H. T., Peden, A. A., & Scheller, R. H. (2001) · Nature · doi:10.1038/35057024 · Cited by 696 · see citing works

Compartmental specificity of cellular membrane fusion encoded in SNARE proteins

McNew, J. A., Parlati, F., Fukuda, R., Johnston, R. J., Paz, K., Paumet, F., Söllner, T. H., & Rothman, J. E. (2000) · Nature · doi:10.1038/35025000 · Cited by 691 · see citing works

SNAREs are concentrated in cholesterol‐dependent clusters that define docking and fusion sites for exocytosis

Lang, T., Bruns, D., Wenzel, D., Riedel, D., Holroyd, P., Thiele, C., & Jahn, R. (2001) · The EMBO Journal · doi:10.1093/emboj/20.9.2202 · Cited by 686 · see citing works

The molecular machinery for secretion is conserved from yeast to neurons.

Bennett, M. K., & Scheller, R. H. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.7.2559 · Cited by 650 · see citing works

SNAREs and traffic

Hong, W. (2005) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2005.03.014 · Cited by 629 · see citing works

SNAPs, a family of NSF attachment proteins involved in intracellular membrane fusion in animals and yeast

Clary, D. O., Griff, I. C., & Rothman, J. E. (1990) · Cell · doi:10.1016/0092-8674(90)90482-t · Cited by 588 · see citing works

Sec18p (NSF)-Driven Release of Sec17p (α-SNAP) Can Precede Docking and Fusion of Yeast Vacuoles

Mayer, A., Wickner, W. T., & Haas, A. (1996) · Cell · doi:10.1016/s0092-8674(00)81084-3 · Cited by 580 · see citing works

VAMP-1: a synaptic vesicle-associated integral membrane protein.

Trimble, W. S., Cowan, D. M., & Scheller, R. H. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.12.4538 · Cited by 575 · see citing works

A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast

Wilson, D. W., Wilcox, C. A., Flynn, G. C., Chen, E., Kuang, W.-J., Henzel, W. J., Block, M. R., Ullrich, A., & Rothman, J. E. (1989) · Nature · doi:10.1038/339355a0 · Cited by 574 · see citing works

Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC‐1/syntaxin.

Blasi, J., Chapman, E. R., Yamasaki, S., Binz, T., Niemann, H., & Jahn, R. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06171.x · Cited by 546 · see citing works

Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain.

Baumert, M., Maycox, P. R., Navone, F., Camilli, P. V. D., & Jahn, R. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb03388.x · Cited by 518 · see citing works

Synaptotagmins: Why So Many?*

Südhof, T. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.r100052200 · Cited by 503 · see citing works

A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles

Søgaard, M., Tani, K., Ye, R. R., Geromanos, S. J., Tempst, P., Kirchhausen, T. L., Rothman, J. E., & Söllner, T. H. (1994) · Cell · doi:10.1016/0092-8674(94)90270-4 · Cited by 503 · see citing works

Trans-complex formation by proteolipid channels in the terminal phase of membrane fusion

Peters, C., Bayer, M. J., Bühler, S., Andersen, J., Mann, M., & Mayer, A. (2001) · Nature · doi:10.1038/35054500 · Cited by 501 · see citing works

Complexins Regulate a Late Step in Ca2+-Dependent Neurotransmitter Release

Reim, K., Mansour, M., Varoqueaux, F., McMahon, H. T., Südhof, T. C., Brose, N., & Rosenmund, C. (2001) · Cell · doi:10.1016/s0092-8674(01)00192-1 · Cited by 500 · see citing works

Synaptotagmin: A Ca2+ sensor that triggers exocytosis?

Chapman, E. (2002) · Nature reviews. Molecular cell biology · doi:10.1038/nrm855 · Cited by 487 · see citing works

Targeting Rab GTPases to distinct membrane compartments

Pfeffer, S. R., & Aivazian, D. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1500 · Cited by 462 · see citing works

Homotypic vacuolar fusion mediated by t- and v-SNAREs

Nichols, B. J., Ungermann, C., Pelham, H. R. B., Wickner, W. T., & Haas, A. (1997) · Nature · doi:10.1038/387199a0 · Cited by 455 · see citing works

Three-Dimensional Structure of the Complexin/SNARE Complex

Chen, X., Tomchick, D. R., Kovrigin, E., Araç, D., Machius, M., Südhof, T. C., & Rizo, J. (2002) · Neuron · doi:10.1016/s0896-6273(02)00583-4 · Cited by 451 · see citing works

SNARE proteins are highly enriched in lipid rafts in PC12 cells: Implications for the spatial control of exocytosis

Chamberlain, L. H., Burgoyne, R. D., & Gould, G. W. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.091502398 · Cited by 432 · see citing works

SNARE Complex Formation Is Triggered by Ca 2+ and Drives Membrane Fusion

Chen, Y. A., Scales, S. J., Patel, S. M., Doung, Y.-C., & Scheller, R. H. (1999) · Cell · doi:10.1016/s0092-8674(00)80727-8 · Cited by 417 · see citing works

Protein-Protein Interactions Contributing to the Specificity of Intracellular Vesicular Trafficking

Calakos, N., Bennett, M. K., Peterson, K. E., & Scheller, R. H. (1994) · Science · doi:10.1126/science.8108733 · Cited by 399 · see citing works

Munc18-1 Promotes Large Dense-Core Vesicle Docking

Voets, T., Toonen, R. F., Brian, E. C., de Wit, H., Moser, T., Rettig, J., Südhof, T. C., Neher, E., & Verhage, M. (2001) · Neuron · doi:10.1016/s0896-6273(01)00391-9 · Cited by 396 · see citing works

Membrane fusion machinery: Insights from synaptic proteins

Südhof, T. C., Camilll, P. D., Niemann, H., & Jahn, R. (1993) · Cell · doi:10.1016/s0092-8674(05)80077-7 · Cited by 388 · see citing works

Rebuilt AAA + motors reveal operating principles for ATP-fuelled machines

Martin, A., Baker, T. A., & Sauer, R. T. (2005) · Nature · doi:10.1038/nature04031 · Cited by 380 · see citing works

Reconstitution of Ca 2+ -Regulated Membrane Fusion by Synaptotagmin and SNAREs

Tucker, W. C., Weber, T., & Chapman, E. R. (2004) · Science · doi:10.1126/science.1097196 · Cited by 374 · see citing works

SNARE Selectivity of the COPII Coat

Mossessova, E., Bickford, L. C., & Goldberg, J. D. (2003) · Cell · doi:10.1016/s0092-8674(03)00608-1 · Cited by 373 · see citing works

Differential Control of the Releasable Vesicle Pools by SNAP-25 Splice Variants and SNAP-23

Sørensen, J. B., Nagy, G., Varoqueaux, F., Nehring, R. B., Brose, N., Wilson, M. C., & Neher, E. (2003) · Cell · doi:10.1016/s0092-8674(03)00477-x · Cited by 364 · see citing works

Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.

Dascher, C., Ossig, R., Gallwitz, D., & Schmitt, H. D. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.2.872 · Cited by 345 · see citing works

Structural Organization of the Synaptic Exocytosis Core Complex

Lin, R. C.-S., & Scheller, R. H. (1997) · Neuron · doi:10.1016/s0896-6273(00)80399-2 · Cited by 344 · see citing works

The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicle recycling.

Walch-Solimena, C., Blasi, J., Edelmann, L., Chapman, E. R., von Mollard, G. F., & Jahn, R. (1995) · The Journal of Cell Biology · doi:10.1083/jcb.128.4.637 · Cited by 331 · see citing works

Mixed and Non-cognate SNARE Complexes

Fasshauer, D., Antonin, W., Margittai, M., Pabst, S., & Jahn, R. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.22.15440 · Cited by 316 · see citing works

SNARE Interactions Are Not Selective

Yang, B., Gonzalez, L. C., Prekeris, R., Steegmaier, M., Advani, R. J., & Scheller, R. H. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.9.5649 · Cited by 315 · see citing works

Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs

Antonin, W., Fasshauer, D., Becker, S., et al. (2002) · Nature Structural Biology · doi:10.1038/nsb746 · Cited by 309 · see citing works

Structure and function of SNARE and SNARE-interacting proteins

Brunger, A. (2005) · Quarterly Reviews of Biophysics (print) · doi:10.1017/s0033583505004051 · Cited by 305 · see citing works

The v-ATPase V 0 Subunit a1 Is Required for a Late Step in Synaptic Vesicle Exocytosis in Drosophila

Hiesinger, P. R., Fayyazuddin, A., Mehta, S., Rosenmund, T., Schulze, K. L., Zhai, R. G., Verstreken, P., Cao, Y., Zhou, Y., Kunz, J., et al. (2005) · Cell · doi:10.1016/j.cell.2005.03.012 · Cited by 295 · see citing works

A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function

Antonin, W., Holroyd, C., Fasshauer, D., Pabst, S., von Mollard, G. F., & Jahn, R. (2000) · The EMBO Journal · doi:10.1093/emboj/19.23.6453 · Cited by 290 · see citing works

Topological restriction of SNARE-dependent membrane fusion

Parlati, F., McNew, J. A., Fukuda, R., Miller, R. B., Söllner, T. H., & Rothman, J. E. (2000) · Nature · doi:10.1038/35025076 · Cited by 287 · see citing works

Vesicle trafficking: pleasure and pain from SM genes

Toonen, R. F. G., & Verhage, M. (2003) · Trends in Cell Biology · doi:10.1016/s0962-8924(03)00031-x · Cited by 281 · see citing works

Folding intermediates of SNARE complex assembly.

Brünger, A. T., Fiebig, K. M., Rice, L. M., et al. (1999) · Nature Structural Biology · doi:10.1038/5803 · Cited by 269 · see citing works

Defects in synaptic vesicle docking in unc-18 mutants

Weimer, R. M., Richmond, J. E., Davis, W. S., Hadwiger, G., Nonet, M. L., & Jørgensen, E. M. (2003) · Nature Neuroscience · doi:10.1038/nn1118 · Cited by 262 · see citing works

Ykt6p, a Prenylated SNARE Essential for Endoplasmic Reticulum-Golgi Transport

McNew, J. A., Søgaard, M., Lampen, N., Machida, S., Ye, R. R., Lacomis, L., Tempst, P., Rothman, J. E., & Söllner, T. H. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.28.17776 · Cited by 248 · see citing works

v‐SNAREs control exocytosis of vesicles from priming to fusion

Borisovska, M., Zhao, Y., Tsytsyura, Y., Glyvuk, N., Takamori, S., Matti, U., Rettig, J., Südhof, T. C., & Bruns, D. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600696 · Cited by 244 · see citing works

Hemifusion in SNARE-mediated membrane fusion

Xu, Y., Zhang, F., Su, Z., et al. (2005) · Nature Structural & Molecular Biology · doi:10.1038/nsmb921 · Cited by 232 · see citing works

A Transient N-terminal Interaction of SNAP-25 and Syntaxin Nucleates SNARE Assembly

Fasshauer, D., & Margittai, M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312064200 · Cited by 219 · see citing works

Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product.

Eakle, K. A., Bernstein, M., & Emr, S. D. (1988) · Molecular and Cellular Biology · doi:10.1128/mcb.8.10.4098 · Cited by 219 · see citing works

Yeast Homotypic Vacuole Fusion: A Window on Organelle Trafficking Mechanisms

Wickner, W. T., & Haas, A. (2000) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.69.1.247 · Cited by 215 · see citing works

Regulation of SNARE complex assembly by an N-terminal domain of the t-SNARE Sso1p

Nicholson, K. L., Munson, M., Miller, R. B., Filip, T. J., Fairman, R., & Hughson, F. M. (1998) · Nature Structural Biology · doi:10.1038/1834 · Cited by 214 · see citing works

Temperature-Sensitive Paralytic Mutations Demonstrate that Synaptic Exocytosis Requires SNARE Complex Assembly and Disassembly

Littleton, J. T., Chapman, E. R., Kreber, R. A., Garment, M. B., Carlson, S. D., & Ganetzky, B. (1998) · Neuron · doi:10.1016/s0896-6273(00)80549-8 · Cited by 211 · see citing works

The N-Ethylmaleimide-sensitive Fusion Protein and α-SNAP Induce a Conformational Change in Syntaxin

Hanson, P. I., Otto, H., Barton, N. R., & Jahn, R. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.28.16955 · Cited by 209 · see citing works

Determinants of liposome fusion mediated by synaptic SNARE proteins

Schuette, C. G., Hatsuzawa, K., Margittai, M., Stein, A., Riedel, D., Küster, P., König, M., Seidel, C. A. M., & Jahn, R. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400044101 · Cited by 208 · see citing works

An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes

Siniossoglou, S., & Pelham, H. R. B. (2001) · The EMBO Journal · doi:10.1093/emboj/20.21.5991 · Cited by 202 · see citing works

Vesicular restriction of synaptobrevin suggests a role for calcium in membrane fusion

Hu, K., Carroll, J., Fedorovich, S. V., et al. (2002) · Nature · doi:10.1038/415646a · Cited by 197 · see citing works

SNAREs Contribute to the Specificity of Membrane Fusion

Scales, S. J., Chen, Y. A., Yoo, B. Y., Patel, S. M., Doung, Y.-C., & Scheller, R. H. (2000) · Neuron · doi:10.1016/s0896-6273(00)81177-0 · Cited by 197 · see citing works

SNARE assembly and disassembly exhibit a pronounced hysteresis

Fasshauer, D., Antonin, W., Subramaniam, V., & Jahn, R. (2002) · Nature Structural Biology · doi:10.1038/nsb750 · Cited by 194 · see citing works

Swf1‐dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation

Taubas, J. V., & Pelham, H. R. B. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600724 · Cited by 194 · see citing works

SNARE complexes and neuroexocytosis: how many, how close?

Montecucco, C., Schiavo, G., & Pantano, S. (2005) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2005.05.002 · Cited by 192 · see citing works

Ordering the Final Events in Yeast Exocytosis

Grote, E., Carr, C. M., & Novick, P. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.2.439 · Cited by 181 · see citing works

Vacuole membrane fusion

Bayer, M. J., Reese, C., Bühler, S., Peters, C., & Mayer, A. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200212004 · Cited by 180 · see citing works

Measuring Distances in Supported Bilayers by Fluorescence Interference-Contrast Microscopy: Polymer Supports and SNARE Proteins

Kiessling, V., & Tamm, L. K. (2003) · Biophysical Journal · doi:10.1016/s0006-3495(03)74861-9 · Cited by 178 · see citing works

Formation, stabilisation and fusion of the readily releasable pool of secretory vesicles

S∅rensen, J. C. (2004) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-004-1247-8 · Cited by 177 · see citing works

Synaptic Core Complex of Synaptobrevin, Syntaxin, and SNAP25 Forms High Affinity -SNAP Binding Site

McMahon, H. T., & Südhof, T. C. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.5.2213 · Cited by 174 · see citing works

The Length of the Flexible SNAREpin Juxtamembrane Region Is a Critical Determinant of SNARE-Dependent Fusion

McNew, J. A., Weber, T., Engelman, D. M., et al. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80343-3 · Cited by 172 · see citing works

A Role of VAMP8/Endobrevin in Regulated Exocytosis of Pancreatic Acinar Cells

Wang, C.-C., Ng, C. P., Lü, L., Atlashkin, V., Zhang, W., Seet, L., & Hong, W. (2004) · Developmental Cell · doi:10.1016/j.devcel.2004.08.002 · Cited by 172 · see citing works

A targeting signal in VAMP regulating transport to synaptic vesicles

Grote, E., Hao, J. C., Bennett, M. K., & Kelly, R. B. (1995) · Cell · doi:10.1016/0092-8674(95)90079-9 · Cited by 168 · see citing works

Sly1 protein bound to Golgi syntaxin Sed5p allows assembly and contributes to specificity of SNARE fusion complexes

Peng, R., & Gallwitz, D. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200202006 · Cited by 165 · see citing works

Longins and their longin domains: regulated SNAREs and multifunctional SNARE regulators

ROSSI, V., Banfield, D. K., Vacca, M., Dietrich, L. E. P., Ungermann, C., D’Esposito, M., Galli, T., & Filippini, F. (2004) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2004.10.002 · Cited by 165 · see citing works

Interactions within the yeast t-SNARE Sso1p that control SNARE complex assembly.

Hughson, F. M., Munson, M., Chen, X., Cocina, A. E., & Schultz, S. M. (2000) · Nature Structural Biology · doi:10.1038/79659 · Cited by 164 · see citing works

Imaging single membrane fusion events mediated by SNARE proteins

Fix, M., Melia, T. J., Jaiswal, J. K., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0401779101 · Cited by 164 · see citing works

Single Molecule Observation of Liposome-Bilayer Fusion Thermally Induced by Soluble N-Ethyl Maleimide Sensitive-Factor Attachment Protein Receptors (SNAREs)

Bowen, M. E., Weninger, K., Brünger, A. T., & Chu, S. (2004) · Biophysical Journal · doi:10.1529/biophysj.104.048637 · Cited by 164 · see citing works

Homotypic fusion of early endosomes: SNAREs do not determine fusion specificity

Brandhorst, D., Zwilling, D., Rizzoli, S. O., Lippert, U., Lang, T., & Jahn, R. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511138103 · Cited by 160 · see citing works

Localization, Dynamics, and Protein Interactions Reveal Distinct Roles for ER and Golgi SNAREs

Hay, J., Klumperman, J., Oorschot, V. M. J., Steegmaier, M., Kuo, C. S., & Scheller, R. H. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.141.7.1489 · Cited by 157 · see citing works

The R-SNARE Endobrevin/VAMP-8 Mediates Homotypic Fusion of Early Endosomes and Late Endosomes

Antonin, W., Holroyd, C., Tikkanen, R., Höning, S., & Jahn, R. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.10.3289 · Cited by 156 · see citing works

TheSaccharomyces cerevisiaev-SNARE Vti1p Is Required for Multiple Membrane Transport Pathways to the Vacuole

von Mollard, G. F., & Stevens, T. H. (1999) · Molecular Biology of the Cell · doi:10.1091/mbc.10.6.1719 · Cited by 154 · see citing works

SNARE-Driven, 25-Millisecond Vesicle Fusion In Vitro

Liu, T., Tucker, W. C., Bhalla, A., et al. (2005) · Biophysical Journal · doi:10.1529/biophysj.105.062539 · Cited by 151 · see citing works

The R-SNARE Motif of Tomosyn Forms SNARE Core Complexes with Syntaxin 1 and SNAP-25 and Down-regulates Exocytosis

Hatsuzawa, K., Lang, T., Fasshauer, D., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305500200 · Cited by 147 · see citing works

Asymmetric Requirements for a Rab Gtpase and Snare Proteins in Fusion of Copii Vesicles with Acceptor Membranes

Cao, X., & Barlowe, C. K. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.149.1.55 · Cited by 146 · see citing works

Homo- and Heterooligomeric SNARE Complexes Studied by Site-directed Spin Labeling

Margittai, M., Fasshauer, D., Pabst, S., Jahn, R., & Langen, R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m010653200 · Cited by 146 · see citing works

Tracking SNARE Complex Formation in Live Endocrine Cells

An, S. J., & Almers, W. (2004) · Science · doi:10.1126/science.1102559 · Cited by 143 · see citing works

Structural insights into the SNARE mechanism

Fasshauer, D. (2003) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(03)00090-9 · Cited by 143 · see citing works

SNARE-Mediated Lipid Mixing Depends on the Physical State of the Vesicles

Chen, X., Araç, D., Wang, T.-M., Gilpin, C. J., Zimmerberg, J. J., & Rizo, J. (2005) · Biophysical Journal · doi:10.1529/biophysj.105.071415 · Cited by 142 · see citing works

Neuronal SNAREs Do Not Trigger Fusion between Synthetic Membranes but Do Promote PEG-Mediated Membrane Fusion

Dennison, S. M., Bowen, M. E., Brünger, A. T., et al. (2005) · Biophysical Journal · doi:10.1529/biophysj.105.069617 · Cited by 142 · see citing works

Analysis of Sec22p in Endoplasmic Reticulum/Golgi Transport Reveals Cellular Redundancy in SNARE Protein Function

Liu, Y., & Barlowe, C. K. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-04-0204 · Cited by 142 · see citing works

Sequential SNARE Assembly Underlies Priming and Triggering of Exocytosis

Chen, Y. A., Scales, S. J., & Scheller, R. H. (2001) · Neuron · doi:10.1016/s0896-6273(01)00270-7 · Cited by 140 · see citing works

An Autoinhibitory Mechanism for Nonsyntaxin SNARE Proteins Revealed by the Structure of Ykt6p

Tochio, H., Tsui, M. M. K., Banfield, D. K., & Zhang, M. (2001) · Science · doi:10.1126/science.1062950 · Cited by 140 · see citing works

Vps45p stabilizes the syntaxin homologue Tlg2p and positively regulates SNARE complex formation

Bryant, N. J., & James, D. E. (2001) · The EMBO Journal · doi:10.1093/emboj/20.13.3380 · Cited by 139 · see citing works

SNAREs can promote complete fusion and hemifusion as alternative outcomes

Giraudo, C. G., Hu, C., You, D., et al. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200501093 · Cited by 138 · see citing works

Trans-SNARE pairing can precede a hemifusion intermediate in intracellular membrane fusion

Reese, C., Heise, F., & Mayer, A. (2005) · Nature · doi:10.1038/nature03722 · Cited by 138 · see citing works

Peptide mimics of SNARE transmembrane segments drive membrane fusion depending on their conformational plasticity

Langosch, D., Crane, J. M., Brosig, B., et al. (2001) · Journal of Molecular Biology · doi:10.1006/jmbi.2001.4889 · Cited by 137 · see citing works

Functions of SNAREs in intracellular membrane fusion and lipid bilayer mixing

Ungermann, C., & Langosch, D. (2005) · Journal of Cell Science · doi:10.1242/jcs.02561 · Cited by 137 · see citing works

A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum

Lewis, M. J., Rayner, J. C., & Pelham, H. R. B. (1997) · The EMBO Journal · doi:10.1093/emboj/16.11.3017 · Cited by 135 · see citing works

A Conserved Membrane-spanning Amino Acid Motif Drives Homomeric and Supports Heteromeric Assembly of Presynaptic SNARE Proteins

Laage, R., Rohde, J., Brosig, B., et al. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m910092199 · Cited by 132 · see citing works

SNC1, a yeast homolog of the synaptic vesicle-associated membrane protein/synaptobrevin gene family: genetic interactions with the RAS and CAP genes.

Gerst, J. E., Rodgers, L., Riggs, M. G., & Wigler, M. H. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.10.4338 · Cited by 131 · see citing works

Single-molecule studies of SNARE complex assembly reveal parallel and antiparallel configurations

Weninger, K., Bowen, M. E., Chu, S., & Brünger, A. T. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2036428100 · Cited by 123 · see citing works

Synaptophysin I Controls the Targeting of VAMP2/Synaptobrevin II to Synaptic Vesicles

Pennuto, M., Bonanomi, D., Benfenati, F., & Valtorta, F. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e03-06-0380 · Cited by 123 · see citing works

SNAREs in native plasma membranes are active and readily form core complexes with endogenous and exogenous SNAREs

Lang, T., Margittai, M., Hölzler, H., & Jahn, R. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200203088 · Cited by 119 · see citing works

Geranylgeranylated Snares Are Dominant Inhibitors of Membrane Fusion

Grote, E., Baba, M., Ohsumi, Y., et al. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.2.453 · Cited by 119 · see citing works

Sec17p and HOPS, in distinct SNARE complexes, mediate SNARE complex disruption or assembly for fusion

Collins, K. M., Thorngren, N., Fratti, R. A., & Wickner, W. T. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600658 · Cited by 116 · see citing works

Structural Analysis of the Neuronal SNARE Protein Syntaxin-1A,

Lerman, J. C., Robblee, J. P., Fairman, R., et al. (2000) · Biochemistry · doi:10.1021/bi0003994 · Cited by 116 · see citing works

Structural Basis for the Inhibitory Role of Tomosyn in Exocytosis

Pobbati, A. V., Razeto, A., Böddener, M., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408767200 · Cited by 116 · see citing works

Membrane Fusion in Eukaryotic Cells

Mayer, A. (2002) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.18.032202.114809 · Cited by 115 · see citing works

Membrane Fusion Mediated by Coiled Coils: A Hypothesis

Bentz, J. (2000) · Biophysical Journal · doi:10.1016/s0006-3495(00)76646-x · Cited by 113 · see citing works

Calcium-independent stimulation of membrane fusion and SNAREpin formation by synaptotagmin I

Mahal, L. K., Sequeira, S. M., Gureasko, J. M., & Söllner, T. H. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200203135 · Cited by 106 · see citing works

Dsl1p, Tip20p, and the Novel Dsl3(Sec39) Protein Are Required for the Stability of the Q/t-SNARE Complex at the Endoplasmic Reticulum in Yeast

Kraynack, B. A., Chan, A., Rosenthal, E. H., Essid, M., Umansky, B., Waters, M. G., & Schmitt, H. D. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-01-0056 · Cited by 106 · see citing works

A SNARE required for retrograde transport to the endoplasmic reticulum

Burri, L., Varlamov, O., Doege, C. A., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1734000100 · Cited by 103 · see citing works

A Direct Interaction between Cdc42 and Vesicle-associated Membrane Protein 2 Regulates SNARE-dependent Insulin Exocytosis*

Nevins, A. K., & Thurmond, D. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m409528200 · Cited by 101 · see citing works

Model organisms lead the way to protein palmitoyltransferases

Linder, M. E., & Deschenes, R. J. (2004) · Journal of Cell Science · doi:10.1242/jcs.00989 · Cited by 101 · see citing works

Amisyn, a Novel Syntaxin-binding Protein That May Regulate SNARE Complex Assembly

Scales, S. J., Hesser, B. A., Masuda, E. S., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204929200 · Cited by 98 · see citing works

Yeast Golgi SNARE interactions are promiscuous

Tsui, M. M. K., & Banfield, D. K. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.1.145 · Cited by 97 · see citing works

The specificity of SNARE-dependent fusion is encoded in the SNARE motif

Paumet, F., Rahimian, V., & Rothman, J. E. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400271101 · Cited by 94 · see citing works

A Novel SNARE N-terminal Domain Revealed by the Crystal Structure of Sec22b

Gonzalez, L. C., Weis, W. I., & Scheller, R. H. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101584200 · Cited by 94 · see citing works

The Di-leucine Motif of Vesicle-associated Membrane Protein 4 Is Required for Its Localization and AP-1 Binding

Peden, A. A., Park, G. Y., & Scheller, R. H. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106646200 · Cited by 93 · see citing works

Cholesterol-dependent Syntaxin-4 and SNAP-23 Clustering Regulates Caveolar Fusion with the Endothelial Plasma Membrane

Predescu, S. A., Predescu, D. N., Shimizu, K., Klein, I., & Malik, A. B. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m505659200 · Cited by 89 · see citing works

Use1p is a yeast SNARE protein required for retrograde traffic to the ER

Dilcher, M., Veith, B., Chidambaram, S., et al. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg339 · Cited by 88 · see citing works

Abl Interactor 1 (Abi-1) Wave-Binding and SNARE Domains Regulate Its Nucleocytoplasmic Shuttling, Lamellipodium Localization, and Wave-1 Levels

Echarri, A., Lai, M. J., Robinson, M. R., & Pendergast, A. M. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.11.4979-4993.2004 · Cited by 88 · see citing works

Regulation of SNAREs by tomosyn and ROCK

Sakisaka, T., Baba, T., Tanaka, S., et al. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200405002 · Cited by 82 · see citing works

A Journey from Mammals to Yeast with Vacuolar H+-ATPase (V-ATPase)

Nelson, N. (2003) · Journal of Bioenergetics and Biomembranes · doi:10.1023/a:1025768529677 · Cited by 81 · see citing works

The SNARE Ykt6 mediates protein palmitoylation during an early stage of homotypic vacuole fusion

Dietrich, L. E. P., Gurezka, R., Veit, M., & Ungermann, C. (2003) · The EMBO Journal · doi:10.1038/sj.emboj.7600015 · Cited by 79 · see citing works

Defining the SNARE Complex Binding Surface of α-SNAP

Marz, K. E., Lauer, J. M., & Hanson, P. I. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m302003200 · Cited by 77 · see citing works

Self-association of the H3 Region of Syntaxin 1A

Misura, K. M. S., Scheller, R. H., & Weis, W. I. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009636200 · Cited by 75 · see citing works

Mechanical Coupling via the Membrane Fusion SNARE Protein Syntaxin 1A: A Molecular Dynamics Study

Knecht, V., & Grubmüller, H. (2003) · Biophysical Journal · doi:10.1016/s0006-3495(03)74965-0 · Cited by 72 · see citing works

Crystal Structure and Biophysical Properties of a Complex between the N-terminal SNARE Region of SNAP25 and Syntaxin 1a

Misura, K. M. S., Gonzalez, L. C., May, A. P., Scheller, R. H., & Weis, W. I. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106853200 · Cited by 69 · see citing works

Cleavage of cellubrevin by tetanus toxin does not affect fusion of early endosomes.

Link, E., McMahon, H. T., von Mollard, G. F., Yamasaki, S., Niemann, H., Südhof, T. C., & Jahn, R. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)46640-3 · Cited by 66 · see citing works

The ionic layer is required for efficient dissociation of the SNARE complex by α-SNAP and NSF

Scales, S. J., Yoo, B. Y., & Scheller, R. H. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.251547598 · Cited by 65 · see citing works

Control of eukaryotic membrane fusion by N-terminal domains of SNARE proteins

Dietrich, L. E. P., Boeddinghaus, C., LaGrassa, T. J., & Ungermann, C. (2003) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(03)00094-6 · Cited by 61 · see citing works

Functional Analysis of Conserved Structural Elements in Yeast Syntaxin Vam3p

Wang, Y., Dulubova, I., Rizo, J., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101644200 · Cited by 58 · see citing works

Targeting of the Synaptic Vesicle Protein Synaptobrevin in the Axon of Cultured Hippocampal Neurons: Evidence for Two Distinct Sorting Steps

West, A. E., Neve, R. L., & Buckley, K. M. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.139.4.917 · Cited by 57 · see citing works

The Cytoplasmic Domain of Vamp4 and Vamp5 Is Responsible for Their Correct Subcellular Targeting

Zeng, Q., Tran, T. T. H., Tan, H.-X., & Hong, W. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303214200 · Cited by 56 · see citing works

Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog

Misura, K. M. S., Bock, J. B., Gonzalez, L. C., Scheller, R. H., & Weis, W. I. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.132274599 · Cited by 54 · see citing works

The Membrane-Dipped Neuronal SNARE Complex: A Site-Directed Spin Labeling Electron Paramagnetic Resonance Study

Kweon, D., Kim, C. S., & Shin, Y. (2002) · Biochemistry · doi:10.1021/bi025934+ · Cited by 43 · see citing works

The Four-helix Bundle of the Neuronal Target Membrane SNARE Complex Is Neither Disordered in the Middle nor Uncoiled at the C-terminal Region

Zhang, F., Chen, Y., Kweon, D., Kim, C. S., & Shin, Y. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201200200 · Cited by 42 · see citing works

Thermal Fluctuations of Red Blood Cell Membrane via a Constant-Area Particle-Dynamics Model

Marcelli, G., Parker, K. H., & Winlove, C. P. (2005) · Biophysical Journal · doi:10.1529/biophysj.104.056168 · Cited by 37 · see citing works

Solution Structure of the Vam7p PX Domain ,

Lu, J., García, J. V., Dulubova, I., et al. (2002) · Biochemistry · doi:10.1021/bi020050b · Cited by 36 · see citing works

Protein–protein interactions in intracellular membrane fusion

Misura, K. M. S., May, A. P., & Weis, W. I. (2000) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(00)00151-2 · Cited by 29 · see citing works

SNAREs Involved in Traffic through the Golgi ComplexPreprint

Pelham, H. R. B., Banfield, D. K., & Lewis, M. J. (1995) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1995.060.01.013 · Cited by 21 · see citing works

IMPLICATIONS FOR INTERMEDIATES IN SNARE COMPLEX ASSEMBLY

Misura, K. M. S., Scheller, R. H., & Weis, W. I. (2001) · Cited by 16 · see citing works

An intramolecular t-SNARE complex functions in vivo without the syntaxin NH2-terminal regulatory domain

Komen, J. S. V., Bai, X., Scott, B. L., & McNew, J. A. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200507138 · Cited by 12 · see citing works

Shedding light on the cell biology of extracellular vesicles

van Niel, G., D'Angelo, G., & Raposo, G. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.125 · Cited by 8,369 · see citing works

Calcium Signaling

Clapham, D. E. (2007) · Cell · doi:10.1016/j.cell.2007.11.028 · Cited by 4,175 · see citing works

The oxytocin receptor: from intracellular signaling to behavior

Jurek, B., & Neumann, I. D. (2018) · Physiological Reviews · doi:10.1152/physrev.00031.2017 · Cited by 999 · see citing works

Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme

White, J. M., Delos, S. E., Brecher, M., & Schornberg, K. (2008) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230802058320 · Cited by 892 · see citing works

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

PSP Genetics Study Group, Höglinger, G. U., Melhem, N. M., Dickson, D. W., Sleiman, P. M. A., Wang, L.-S., Klei, L., Rademakers, R., de Silva, R., Litvan, I., et al. (2011) · Nature Genetics · doi:10.1038/ng.859 · Cited by 603 · see citing works

Computed structures of core eukaryotic protein complexes

Humphreys, I. R., Pei, J., Baek, M., Krishnakumar, A., Anishchenko, I., Ovchinnikov, S., Zhang, J., Ness, T. J., Banjade, S., Bagde, S. R., et al. (2021) · Science · doi:10.1126/science.abm4805 · Cited by 542 · see citing works

Current views on type 2 diabetes

Lin, Y., & Sun, Z. (2010) · Journal of Endocrinology · doi:10.1677/joe-09-0260 · Cited by 457 · see citing works

Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretion

Verkhratsky, A., Matteoli, M., Parpura, V., Mothet, J., & Zorec, R. (2016) · The EMBO Journal · doi:10.15252/embj.201592705 · Cited by 397 · see citing works

The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones

Imig, C., Min, S.-W., Krinner, S., Arancillo, M., Rosenmund, C., Südhof, T. C., Rhee, J., Brose, N., & Cooper, B. H. (2014) · Neuron · doi:10.1016/j.neuron.2014.10.009 · Cited by 389 · see citing works

ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation

Miao, G., Zhao, H., Li, Y., Ji, M., Chen, Y., Shi, Y., Bi, Y., Wang, P., & Zhang, H. (2021) · Developmental Cell · doi:10.1016/j.devcel.2020.12.010 · Cited by 354 · see citing works

Munc13 mediates the transition from the closed syntaxin–Munc18 complex to the SNARE complex

Ma, C., Li, W., Xu, Y., & Rizo, J. (2011) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2047 · Cited by 363 · see citing works

Rab5 is necessary for the biogenesis of the endolysosomal system in vivo

Zeigerer, A., Gilleron, J., Bogorad, R. L., Marsico, G., Nonaka, H., Seifert, S., Epstein-Barash, H., Kuchimanchi, S., Peng, C. G., Ruda, V. M., et al. (2012) · Nature · doi:10.1038/nature11133 · Cited by 362 · see citing works

The Vici Syndrome Protein EPG5 Is a Rab7 Effector that Determines the Fusion Specificity of Autophagosomes with Late Endosomes/Lysosomes

Wang, Z., Miao, G., Xue, X., Guo, X., Yuan, C., Wang, Z., Zhang, G., Chen, Y., Feng, D., Hu, J., et al. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.08.021 · Cited by 321 · see citing works

Synaptic vesicle recycling: steps and principles

Rizzoli, S. O. (2014) · The EMBO Journal · doi:10.1002/embj.201386357 · Cited by 317 · see citing works

Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spines

Kennedy, M. J., Davison, I. G., Robinson, C. G., & Ehlers, M. D. (2010) · Cell · doi:10.1016/j.cell.2010.02.042 · Cited by 294 · see citing works

Conformational switch of syntaxin-1 controls synaptic vesicle fusion

Gerber, S. H., Rah, J.-C., Min, S.-W., Liu, X., de Wit, H., Dulubova, I., Meyer, A. C., Rizo, J., Arancillo, M., Hammer, R. E., et al. (2008) · Science · doi:10.1126/science.1163174 · Cited by 294 · see citing works

SNAREing immunity: the role of SNAREs in the immune system

Stow, J. L., Manderson, A. P., & Murray, R. Z. (2006) · Nature Reviews Immunology · doi:10.1038/nri1980 · Cited by 235 · see citing works

Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders

Fraldi, A., Annunziata, F., Lombardi, A., Kaiser, H., Medina, D. L., Spampanato, C., Fedele, A. O., Polishchuk, R., Sorrentino, N. C., Simons, K., et al. (2010) · The EMBO Journal · doi:10.1038/emboj.2010.237 · Cited by 225 · see citing works

Lysosomal cell death mechanisms in aging

Gómez-Sintes, R., Ledesma, M. D., & Boya, P. (2016) · Ageing Research Reviews · doi:10.1016/j.arr.2016.02.009 · Cited by 216 · see citing works

Astrocyte lipid metabolism is critical for synapse development and function in vivo

van Deijk, A. F., Camargo, N., Timmerman, J., Heistek, T., Brouwers, J. F., Mogavero, F., Mansvelder, H. D., Smit, A. B., & Verheijen, M. H. G. (2017) · Glia · doi:10.1002/glia.23120 · Cited by 201 · see citing works

The Genomic and Cellular Foundations of Animal Origins

Richter, D. J., & King, N. (2013) · Annual Review of Genetics · doi:10.1146/annurev-genet-111212-133456 · Cited by 196 · see citing works

Neuropeptide exocytosis involving synaptotagmin-4 and oxytocin in hypothalamic programming of body weight and energy balance

Zhang, G., Bai, H., Zhang, H., Dean, C., Wu, Q., Li, J., Guariglia, S., Meng, Q., & Cai, D. (2011) · Neuron · doi:10.1016/j.neuron.2010.12.036 · Cited by 208 · see citing works

Endocytosis and Autophagy: Exploitation or Cooperation?

Tooze, S. A., Abada, A., & Elazar, Z. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a018358 · Cited by 202 · see citing works

From the stochasticity of molecular processes to the variability of synaptic transmission

Ribrault, C., Sekimoto, K., & Triller, A. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3025 · Cited by 198 · see citing works

SNAREopathies: Diversity in Mechanisms and Symptoms

Verhage, M., & Sørensen, J. B. (2020) · Neuron · doi:10.1016/j.neuron.2020.05.036 · Cited by 121 · see citing works

Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system

Xue, M., Stradomska, A., Chen, H., Brose, N., Zhang, W., Rosenmund, C., & Reim, K. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803012105 · Cited by 137 · see citing works

SNAP‐25 in Neuropsychiatric Disorders

Corradini, I., Verderio, C., Sala, M., Wilson, M. C., & Matteoli, M. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2008.03995.x · Cited by 128 · see citing works

Genetic interactions reveal the evolutionary trajectories of duplicate genes

VanderSluis, B., Bellay, J., Musso, G., Costanzo, M., Papp, B., Vizeacoumar, F. J., Baryshnikova, A., Andrews, B., Boone, C., & Myers, C. L. (2010) · Molecular Systems Biology · doi:10.1038/msb.2010.82 · Cited by 110 · see citing works

Understanding a protein fold: The physics, chemistry, and biology of α-helical coiled coils

Woolfson, D. N. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.104579 · Cited by 106 · see citing works

Escapement mechanisms and the conversion of disequilibria; the engines of creation

Branscomb, E., Biancalani, T., Goldenfeld, N., & Russell, M. (2017) · Physics Reports · doi:10.1016/j.physrep.2017.02.001 · Cited by 96 · see citing works

Amyloid-β Oligomers May Impair SNARE-Mediated Exocytosis by Direct Binding to Syntaxin 1a

Yang, Y., Kim, J., Kim, H. Y., Ryoo, N., Lee, S., Kim, Y., Rhim, H., & Shin, Y.-K. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.07.044 · Cited by 88 · see citing works

Syntaxin-3 regulates newcomer insulin granule exocytosis and compound fusion in pancreatic beta cells

Zhu, D., Koo, E., Kwan, E., Kang, Y., Park, S., Xie, H., Sugita, S., & Gaisano, H. Y. (2013) · Diabetologia · doi:10.1007/s00125-012-2757-0 · Cited by 81 · see citing works

An Ancient Duplication of Exon 5 in the Snap25 Gene Is Required for Complex Neuronal Development/Function

Johansson, J. U., Ericsson, J., Janson, J., Beraki, S., Stanić, D., Mandic, S. A., Wikström, M. A., Hökfelt, T., Ögren, S. O., Rozell, B., et al. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000278 · Cited by 83 · see citing works

Reduced SNAP‐25 alters short‐term plasticity at developing glutamatergic synapses

Antonucci, F., Corradini, I., Morini, R., Fossati, G., Menna, E., Pozzi, D., Pacioni, S., Verderio, C., Bacci, A., & Matteoli, M. (2013) · The EMBO Reports · doi:10.1038/embor.2013.75 · Cited by 71 · see citing works

Extracellular vesicle PD‐L1 in reshaping tumor immune microenvironment: biological function and potential therapy strategies

Liu, J., Peng, X., Yang, S., Li, X., Huang, M., Wei, S., Zhang, S., He, G., Zheng, H., Fan, Q., et al. (2022) · Cell Communication and Signaling · doi:10.1186/s12964-021-00816-w · Cited by 75 · see citing works

Membrane raft domains and remodeling in aging brain

Colin, J., Gregory-Pauron, L., Lanhers, M.-C., Claudepierre, T., Corbier, C., Yen, F. T., Malaplate-Armand, C., & Oster, T. (2016) · Biochimie · doi:10.1016/j.biochi.2016.08.014 · Cited by 55 · see citing works

Intelligence in Williams Syndrome is related to STX1A, which encodes a component of the presynaptic SNARE complex

Gao, M. C., Bellugi, U., Dai, L., Mills, D. L., Sobel, E. M., Lange, K., & Korenberg, J. R. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010292 · Cited by 42 · see citing works

The protein secretory pathway of <i>Candida albicans</i>

Fonzi, W. A. (2009) · Mycoses · doi:10.1111/j.1439-0507.2008.01673.x · Cited by 25 · see citing works

Atomic-Resolution Simulations Yield New Insight into Vesicle Fusion and Fusion Protein Mechanisms

Kasson, P. M., Lindahl, E. R., & Pande, V. S. (2010) · Biophysical Journal · doi:10.1016/j.bpj.2009.12.3363

Leaky Intermediates and Possible Dead-End Configurations in Membrane Fusion

Molotkovskiy, R. Y., Galimzyanov, T. R., Kuzmin, P., et al. (2018) · Biophysical Journal · doi:10.1016/j.bpj.2017.11.3313

Effect of Phosphatidylserine on Asymmetric Membrane Fusion

Vázquez, G. D., Chakraborty, H., Tarafdar, P. K., et al. (2012) · Biophysical Journal · doi:10.1016/j.bpj.2011.11.2742

Protein Modulation of Liposome Fusion

Hong, K., Düzgüneş, N., Meers, P. R., et al. (1987) · Springer eBooks · doi:10.1007/978-1-4757-9598-1_12 · Cited by 8 · see citing works

Membrane fusion: Kinetics and mechanisms

Bentz, J., & Ellens, H. M. (1987) · Colloids and Surfaces · doi:10.1016/0166-6622(87)80204-4 · Cited by 94 · see citing works