Blackshaw, Seth

RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention

Donnelly, C. J., Zhang, P.-W., Pham, J. T., Haeusler, A. R., Mistry, N. A., Vidensky, S., Daley, E. L., Poth, E. M., Hoover, B., Fines, D. M., et al. (2013) · Neuron

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative Diseases

Cited by 877

Serine racemase: A glial enzyme synthesizing d -serine to regulate glutamate- N -methyl- d -aspartate neurotransmission

Wolosker, H., Blackshaw, S., & Snyder, S. H. (1999) · Proceedings of the National Academy of Sciences

Amino Acid Enzymes and MetabolismNeuroscience and Neuropharmacology Research

Cited by 811

Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche

Lee, D. A., Bedont, J. L., Pak, T., Wang, H., Song, J., Miranda-Angulo, A., Takiar, V., Charubhumi, V., Balordi, F., Takebayashi, H., et al. (2012) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsRegulation of Appetite and Obesity

Cited by 502

A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1

Wang, Y., An, R., Umanah, G. K., Park, H., Nambiar, K., Eacker, S. M., Kim, B., Bao, L., Harraz, M. M., Chang, C., et al. (2016) · Science

Cell death mechanisms and regulationMacrophage Migration Inhibitory Factor

Cited by 421

The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing

Barry, G., Briggs, J. A., Vanichkina, D. P., Poth, E. M., Beveridge, N. J., Ratnu, V. S., Nayler, S. P., Nones, K., Hu, J., Bredy, T. W., et al. (2014) · Molecular Psychiatry

Cancer-related molecular mechanisms researchRNA Research and Splicing

Cited by 394

A genomic atlas of mouse hypothalamic development

Shimogori, T., Lee, D. A., Miranda-Angulo, A., Yang, Y., Wang, H., Jiang, L., Yoshida, A. C., Kataoka, A., Mashiko, H., Avetisyan, M., et al. (2010) · Nature Neuroscience

Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms

Cited by 382

Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy

Watkins, C. C., Sawa, A., Jaffrey, S., Blackshaw, S., Barrow, R. K., Snyder, S. H., & Ferris, C. D. (2000) · Journal of Clinical Investigation

Gastrointestinal motility and disordersNitric Oxide and Endothelin Effects

Cited by 268

ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration

Wang, J., Zibetti, C., Shang, P., Sripathi, S. R., Zhang, P., Cano, M., Hoang, T., Xia, S., Ji, H., Merbs, S. L., et al. (2018) · Nature Communications

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 185

ASCOT identifies key regulators of neuronal subtype-specific splicing

Ling, J. P., Wilks, C., Charles, R., Leavey, P. J., Ghosh, D., Jiang, L., Santiago, C. P., Pang, B., Venkataraman, A., Clark, B. S., et al. (2020) · Nature Communications

RNA Research and SplicingRNA regulation and disease

Cited by 107

Three-dimensional diffusion tensor microimaging for anatomical characterization of the mouse brain

Aggarwal, M., Mori, S., Shimogori, T., Blackshaw, S., & Zhang, J. (2010) · Magnetic Resonance in Medicine

Advanced Neuroimaging Techniques and ApplicationsAdvanced MRI Techniques and Applications

Cited by 90

Dual midbrain and forebrain origins of thalamic inhibitory interneurons

Jager, P., Moore, G., Calpin, P., Durmishi, X., Salgarella, I., Menage, L., Kita, Y., Wang, Y., Kim, D. W., Blackshaw, S., et al. (2021) · eLife

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 61

Ptbp1 deletion does not induce astrocyte-to-neuron conversion

Hoang, T., Kim, D. W., Appel, H., Ozawa, M., Zheng, S., Kim, J., & Blackshaw, S. (2023) · Nature

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 60

An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks

Bedont, J. L., LeGates, T. A., Buhr, E., Bathini, A., Ling, J. P., Bell, B., Wu, M. N., Wong, P. C., Van Gelder, R. N., Mongrain, V., et al. (2017) · Current Biology

Circadian rhythm and melatoninSleep and Wakefulness Research

Cited by 41

Elevated nuclear TDP-43 induces constitutive exon skipping

Carmen-Orozco, R. P., Tsao, W., Ye, Y., Sinha, I. R., Chang, K., Trinh, V., Chung, W., Bowden, K., Troncoso, J. C., Blackshaw, S., et al. (2023) · Molecular Neurodegeneration

Amyotrophic Lateral Sclerosis ResearchRNA Research and Splicing

Cited by 27

Elevated nuclear TDP-43 induces constitutive exon skipping

Carmen-Orozco, R. P., Tsao, W., Ye, Y., Sinha, I. R., Chang, K., Trinh, V. T., Chung, W., Bowden, K., Troncoso, J. C., Blackshaw, S., et al. (2024) · Molecular Neurodegeneration

Amyotrophic Lateral Sclerosis ResearchRNA Research and Splicing

Cited by 27