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The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration

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Integrated Microprism and Microelectrode Array for Simultaneous Electrophysiology and Two‐Photon Imaging across All Cortical Layers

Yang, Q., Wu, B., Castagnola, E., Pwint, M. Y., Williams, N. P., Vazquez, A. L., & Cui, X. T. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202302362 · Cited by 13 · see citing works

Genetic variation in cis-regulatory domains suggests cell type-specific regulatory mechanisms in immunity

Avalos, D., Rey, G., Ribeiro, D. M., Ramisch, A., Dermitzakis, E. T., & Delaneau, O. (2023) · Communications Biology · doi:10.1038/s42003-023-04688-3 · Cited by 13 · see citing works

Shared genetic aetiology of Alzheimer’s disease and age-related macular degeneration by APOC1 and APOE genes

Zhang, X., Zhu, Z., Huang, Y., Shang, X., O'Brien, T. J., Kwan, P., Ha, J. J., Wang, W., Liu, S., Zhang, X., et al. (2024) · BMJ Neurology Open · doi:10.1136/bmjno-2023-000570 · Cited by 12 · see citing works

Building a Mammalian Retina: An Eye on Chromatin Structure

Daghsni, M., & Aldiri, I. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.775205 · Cited by 11 · see citing works

Machine Learning Prediction of Non-Coding Variant Impact in Human Retinal cis -Regulatory Elements

VandenBosch, L. S., Luu, K., Timms, A. E., Challam, S., Wu, Y., Lee, A., & Cherry, T. J. (2022) · Translational Vision Science & Technology · doi:10.1167/tvst.11.4.16 · Cited by 11 · see citing works

Age- and sex- divergent translatomic responses of the mouse retinal pigmented epithelium

Chucair‐Elliott, A. J., Ocañas, S. R., Pham, K. D., Machalinski, A. H., Plafker, S. M., Stout, M. B., Elliott, M. H., & Freeman, W. M. (2024) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2024.04.012 · Cited by 11 · see citing works

Optimized assay for transposase-accessible chromatin by sequencing (ATAC-seq) library preparation from adult Drosophila melanogaster neurons

Merrill, C. B., Pabon, M. A., Montgomery, A., Rodan, A. R., & Rothenfluh, A. (2022) · Scientific Reports · doi:10.1038/s41598-022-09869-4 · Cited by 10 · see citing works

Genome-wide analysis of genetic pleiotropy and causal genes across three age-related ocular disorders

Yao, X., Yang, H., Han, H., Kou, X., Jiang, Y., Luo, M., Zhou, Y., Wang, J., Fan, X., Wang, X., et al. (2023) · Human Genetics · doi:10.1007/s00439-023-02542-4 · Cited by 11 · see citing works

Novel Epigenetic Clock Biomarkers of Age-Related Macular Degeneration

Mallik, S., Grodstein, F., Bennett, D. A. A., Vavvas, D. G., & Lemos, B. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.856853 · Cited by 10 · see citing works

Assessing transcriptomic reidentification risks using discriminative sequence modelsPreprint

Sadhuka, S., Fridman, D., Berger, B., & Cho, H. (2023) · Genome Research · doi:10.1101/gr.277699.123 · Cited by 10 · see citing works

Disorganized chromatin hierarchy and stem cell aging in a male patient of atypical laminopathy-based progeria mandibuloacral dysplasia type A

Jin, W. Z., Jiang, S., Liu, X., He, Y., Li, T., Ma, J., Chen, Z., Lu, X., Liu, X., Shou, W., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-54338-3 · Cited by 8 · see citing works

Geographical variation in treated psychotic and other mental disorders in Finland by region and urbanicity

Suokas, K., Kurkela, O., Nevalainen, J., Suvisaari, J., Hakulinen, C. A., Kampman, O., & Pirkola, S. P. (2023) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-023-02516-x · Cited by 9 · see citing works

Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model

Luu, J. C., Kallestad, L., Hoang, T. V., Lewandowski, D., Dong, Z., Blackshaw, S., & Palczewski, K. (2020) · Human Molecular Genetics · doi:10.1093/hmg/ddaa158 · Cited by 14 · see citing works

Single-cell multiome and enhancer connectome of human retinal pigment epithelium and choroid nominate pathogenic variants in age-related macular degenerationPreprint

Wang, S. K., Li, J., Nair, S., Korasaju, R., Chen, Y., Zhang, Y., Kundaje, A. B., Liu, Y., Wang, N., & Chang, H. Y. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.21.644670 · Cited by 3 · see citing works

A systems biology approach uncovers novel disease mechanisms in age-related macular degeneration

Orozco, L. D., Owen, L. A., Hofmann, J. W., Stockwell, A., Tao, J., Haller, S., Mukundan, V. T., Clarke, C., Lund, J. M., Sridhar, A., et al. (2023) · Cell Genomics · doi:10.1016/j.xgen.2023.100302 · Cited by 51 · see citing works

Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4, and TNXB genes

Porter, L. F., Saptarshi, N., Fang, Y., Rathi, S., den Hollander, A. I., de Jong, E. K., Clark, S. J., Bishop, P. N., Olsen, T. W., Liloglou, T., et al. (2019) · Clinical Epigenetics · doi:10.1186/s13148-019-0608-2 · Cited by 61 · see citing works

Single-cell multiome and enhancer connectome of human retinal pigment epithelium and choroid nominate causal variants in macular degeneration

Wang, S. K., Li, J., Nair, S., Kosaraju, R., Chen, Y., Zhang, Y., Kundaje, A. B., Liu, Y., Wang, N., & Chang, H. Y. (2026) · Cell Reports · doi:10.1016/j.celrep.2025.116814 · Cited by 7 · see citing works