Mitch, William E.

Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

Brenner, B. M., Cooper, M. E., de Zeeuw, D., Keane, W. F., Mitch, W. E., Parving, H.-H., Remuzzi, G., Snapinn, S. M., Zhang, Z., & Shahinfar, S. (2001) · New England Journal of Medicine

Chronic Kidney Disease and DiabetesRenin-Angiotensin System Studies

Cited by 7,493

Diabetes and Cardiovascular Disease: A Statement for Healthcare Professionals From the American Heart Association

Grundy, S. M., Benjamin, I. J., Burke, G. L., Chait, A., Eckel, R. H., Howard, B. V., Mitch, W., Smith, S. C., & Sowers, J. R. (1999) · Circulation

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and Management

Cited by 2,698

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

Landmesser, U., Dikalov, S., Price, S. R., McCann, L., Fukai, T., Holland, S. M., Mitch, W. E., & Harrison, D. G. (2003) · Journal of Clinical Investigation

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 1,660

Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

Lecker, S. H., Jagoe, R. T., Gilbert, A., Gomes, M., Baracos, V., Bailey, J., Price, S. R., Mitch, W. E., & Goldberg, A. L. (2004) · The FASEB Journal

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 1,539

AHA Dietary Guidelines: Revision 2000: A Statement for Healthcare Professionals From the Nutrition Committee of the American Heart Association

Krauss, R. M., Eckel, R. H., Howard, B., Appel, L. J., Daniels, S. R., Deckelbaum, R. J., Erdman, J. W., Kris-Etherton, P., Goldberg, I. J., Kotchen, T. A., et al. (2000) · Circulation

Nutritional Studies and DietCardiovascular Health and Risk Factors

Cited by 1,458

Protein degradation by the ubiquitin-proteasome pathway in normal and disease states

Lecker, S. H., Goldberg, A. L., & Mitch, W. E. (2006) · Journal of the American Society of Nephrology

Ubiquitin and proteasome pathwaysRespiratory Support and Mechanisms

Cited by 1,234

Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling

Wang, X., Hu, Z., Hu, J., Du, J., & Mitch, W. E. (2006) · Endocrinology

Muscle Physiology and DisordersMuscle metabolism and nutrition

Cited by 600

The risk of developing end-stage renal disease in patients with type 2 diabetes and nephropathy: the RENAAL study

Keane, W. F., Brenner, B. M., de Zeeuw, D., Grunfeld, J.-P., McGill, J., Mitch, W. E., Ribeiro, A. B., Shahinfar, S., Simpson, R. L., Snapinn, S. M., et al. (2003) · Kidney International

Chronic Kidney Disease and DiabetesAcute Kidney Injury Research

Cited by 539

Myostatin/activin pathway antagonism: molecular basis and therapeutic potential

Han, H. Q., Zhou, X., Mitch, W. E., & Goldberg, A. L. (2013) · The International Journal of Biochemistry & Cell Biology

Muscle Physiology and DisordersTGF-β signaling in diseases

Cited by 314

Requirement of argininosuccinate lyase for systemic nitric oxide production

Erez, A., Nagamani, S. C. S., Shchelochkov, O. A., Premkumar, M. H., Campeau, P. M., Chen, Y., Garg, H. K., Li, L., Mian, A., Bertin, T. K., et al. (2011) · Nature Medicine

Nitric Oxide and Endothelin EffectsAmino Acid Enzymes and Metabolism

Cited by 233

Inhibition of Stat3 Activation Suppresses Caspase-3 and the Ubiquitin-Proteasome System, Leading to Preservation of Muscle Mass in Cancer Cachexia

Silva, K. A. S., Dong, J., Dong, Y., Dong, Y., Schor, N., Tweardy, D. J., Zhang, L., & Mitch, W. E. (2015) · Journal of Biological Chemistry

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 229

Inhibition of myostatin in mice improves insulin sensitivity via irisin-mediated cross talk between muscle and adipose tissues

Dong, J., Dong, Y., Dong, Y., Chen, F., Mitch, W. E., & Zhang, L. (2016) · International Journal of Obesity

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 212

Caspase-3 cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity

Wang, X. H., Zhang, L., Mitch, W. E., LeDoux, J. M., Hu, J., & Du, J. (2010) · Journal of Biological Chemistry

Ubiquitin and proteasome pathwaysMuscle Physiology and Disorders

Cited by 89

Nutritional Considerations in the Treatment of Patients with Chronic Uremia

Mitch, W. E., & Maroni, B. J. (1998) · Mineral and Electrolyte Metabolism

Dialysis and Renal Disease ManagementClinical Nutrition and Gastroenterology

Cited by 17