Larkum, Matthew E.

A new cellular mechanism for coupling inputs arriving at different cortical layers

Larkum, M. E., Zhu, J. J., & Sakmann, B. (1999) · Nature

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 1,180

A cellular mechanism for cortical associations: an organizing principle for the cerebral cortex

Larkum, M. (2013) · Trends in Neurosciences

Neural dynamics and brain functionNeuroscience and Neuropharmacology Research

Cited by 755

Synaptic integration in tuft dendrites of layer 5 pyramidal neurons: a new unifying principle

Larkum, M. E., Nevian, T., Sandler, M., Polsky, A., & Schiller, J. (2009) · Science

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 677

Active properties of neocortical pyramidal neuron dendrites

Major, G., Larkum, M. E., & Schiller, J. (2013) · Annual Review of Neuroscience

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 443

Active cortical dendrites modulate perception

Takahashi, N., Oertner, T. G., Hegemann, P., & Larkum, M. E. (2016) · Science

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 419

Properties of basal dendrites of layer 5 pyramidal neurons: a direct patch-clamp recording study.

Nevian, T., Larkum, M. E., Polsky, A., & Schiller, J. (2007) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 406

Dendritic encoding of sensory stimuli controlled by deep cortical interneurons

Murayama, M., Pérez-Garci, E., Nevian, T., Bock, T., Senn, W., & Larkum, M. E. (2009) · Nature

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 369

Top-down Dendritic Input Increases the Gain of Layer 5 Pyramidal Neurons

Larkum, M. E. (2004) · Cerebral Cortex

Neural dynamics and brain functionNeuroscience and Neuropharmacology Research

Cited by 366

A Top-Down Cortical Circuit for Accurate Sensory Perception

Manita, S., Suzuki, T., Homma, C., Matsumoto, T., Odagawa, M., Yamada, K., Ota, K., Matsubara, C., Inutsuka, A., Sato, M., et al. (2015) · Neuron

Neural dynamics and brain functionTactile and Sensory Interactions

Cited by 365

General anesthesia decouples cortical pyramidal neurons

Suzuki, M., & Larkum, M. E. (2020) · Cell

Neural dynamics and brain functionNeuroscience and Neuropharmacology Research

Cited by 348

Calcium electrogenesis in distal apical dendrites of layer 5 pyramidal cells at a critical frequency of back-propagating action potentials

Larkum, M. E., Kaiser, K. M. M., & Sakmann, B. (1999) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchIon channel regulation and function

Cited by 342

Cellular Mechanisms of Conscious Processing

Aru, J., Suzuki, M., & Larkum, M. E. (2020) · Trends in Cognitive Sciences

Neural dynamics and brain functionPhilosophy and Theoretical Science

Cited by 321

The Cellular Basis of GABA B -Mediated Interhemispheric Inhibition

Palmer, L. M., Schulz, J. M., Murphy, S. C., Ledergerber, D., Murayama, M., & Larkum, M. E. (2012) · Science

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 284

Dendritic spikes in apical dendrites of neocortical layer 2/3 pyramidal neurons

Larkum, M. E., Waters, J., Sakmann, B., & Helmchen, F. (2007) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 274

Active dendritic currents gate descending cortical outputs in perception

Takahashi, N., Ebner, C., Sigl-Glöckner, J., Moberg, S., Nierwetberg, S., & Larkum, M. E. (2020) · Nature Neuroscience

Neural dynamics and brain functionNeuroscience and Neuropharmacology Research

Cited by 231

Cortical dendritic activity correlates with spindle-rich oscillations during sleep in rodents

Seibt, J., Richard, C. J., Sigl-Glöckner, J., Takahashi, N., Kaplan, D. I., Doron, G., de Limoges, D., Bocklisch, C., & Larkum, M. E. (2017) · Nature Communications

Sleep and Wakefulness ResearchNeural dynamics and brain function

Cited by 165

Coupling the State and Contents of Consciousness

Aru, J., Suzuki, M., Rutiku, R., Larkum, M. E., & Bachmann, T. (2019) · Frontiers in Systems Neuroscience

Philosophy and Theoretical ScienceNeural dynamics and brain function

Cited by 164

Perirhinal input to neocortical layer 1 controls learning

Doron, G., Shin, J. N., Takahashi, N., Drüke, M., Bocklisch, C., Skenderi, S., de Mont, L., Toumazou, M., Ledderose, J., Brecht, M., et al. (2020) · Science

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 160

An integrative, multiscale view on neural theories of consciousness

Storm, J. F., Klink, P. C., Aru, J., Senn, W., Goebel, R., Pigorini, A., Avanzini, P., Vanduffel, W., Roelfsema, P. R., Massimini, M., et al. (2024) · Neuron

Philosophy and Theoretical ScienceNeural dynamics and brain function

Cited by 114

A perspective on cortical layering and layer-spanning neuronal elements

Larkum, M. E., Petro, L. S., Sachdev, R. N. S., & Muckli, L. (2018) · Frontiers in Neuroanatomy

Neural dynamics and brain functionNeuroscience and Neuropharmacology Research

Cited by 102

The feasibility of artificial consciousness through the lens of neuroscience

Aru, J., Larkum, M. E., & Shine, J. M. (2023) · Trends in Neurosciences

Philosophy and Theoretical ScienceEmbodied and Extended Cognition

Cited by 98

The effects of arousal on apical amplification and conscious state

Phillips, W. A., Larkum, M. E., Harley, C. W., & Silverstein, S. M. (2016) · Neuroscience of Consciousness

Neural dynamics and brain functionNeuroscience and Neuropharmacology Research

Cited by 75

Dendritic calcium spikes are clearly detectable at the cortical surface

Suzuki, M., & Larkum, M. E. (2017) · Nature Communications

Neural dynamics and brain functionNeuroscience and Neuropharmacology Research

Cited by 70

Memories off the top of your head

Shin, J. N., Doron, G., & Larkum, M. E. (2021) · Science

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 40