Thorens, Bernard

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

Zhou, R., Tardivel, A., Thorens, B., Choi, I., & Tschopp, J. (2010) · Nature Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 2,708

The SLC2 (GLUT) family of membrane transporters

Mueckler, M., & Thorens, B. (2013) · Molecular Aspects of Medicine

Metabolism, Diabetes, and CancerDrug Transport and Resistance Mechanisms

Cited by 1,328

Glucose transporters in the 21st Century

Thorens, B., & Mueckler, M. (2010) · American Journal of Physiology-Endocrinology and Metabolism

Metabolism, Diabetes, and CancerIon Transport and Channel Regulation

Cited by 1,013

Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1.

Thorens, B. (1992) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 906

GLUT2, glucose sensing and glucose homeostasis

Thorens, B. (2015) · Diabetologia

Pancreatic function and diabetesMetabolism, Diabetes, and Cancer

Cited by 722

The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members

Joost, H.-G., & Thorens, B. (2001) · Molecular Membrane Biology

Metabolism, Diabetes, and CancerIon Transport and Channel Regulation

Cited by 719

Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase

Duplain, H., Burcelin, R., Sartori, C., Cook, S., Egli, M., Lepori, M., Vollenweider, P., Pedrazzini, T., Nicod, P., Thorens, B., et al. (2001) · Circulation

Nitric Oxide and Endothelin EffectsDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 533

Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy

Preitner, F., Bonny, O., Laverrière, A., Rotman, S., Firsov, D., Da Costa, A., Metref, S., & Thorens, B. (2009) · Proceedings of the National Academy of Sciences

Gout, Hyperuricemia, Uric AcidBiochemical and Molecular Research

Cited by 284

Expression and Functional Activity of Glucagon, Glucagon-Like Peptide I, and Glucose-Dependent Insulinotropic Peptide Receptors in Rat Pancreatic Islet Cells

Moens, K., Heimberg, H., Flamez, D., Huypens, P., Quartier, E., Ling, Z., Pipeleers, D., Gremlich, S., Thorens, B., & Schuit, F. (1996) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 250

VAMP‐2 and cellubrevin are expressed in pancreatic beta‐cells and are essential for Ca(2+)‐but not for GTP gamma S‐induced insulin secretion.

Regazzi, R., Wollheim, C. B., Lang, J., Theler, J. M., Rossetto, O., Montecucco, C., Sadoul, K., Weller, U., Palmer, M., & Thorens, B. (1995) · The EMBO Journal

Pancreatic function and diabetesCellular transport and secretion

Cited by 233

Leptin Inhibits Directly Glucocorticoid Secretion by Normal Human and Rat Adrenal Gland**This work was supported by a grant from the Swiss National Science Foundation (No. 3100–050748.97/1).

Pralong, F. P., Roduit, R., Waeber, G., Castillo, E., Mosimann, F., Thorens, B., & Gaillard, R. C. (1998) · Endocrinology

Regulation of Appetite and ObesityAdrenal Hormones and Disorders

Cited by 202

Brain glucose sensing and neural regulation of insulin and glucagon secretion

Thorens, B. (2011) · Diabetes, Obesity and Metabolism

Pancreatic function and diabetesDiabetes Management and Research

Cited by 198

Expression of the Glucagon‐Like Peptide‐1 Receptor Gene in Rat Brain

Alvarez, E., Roncero, I., Chowen, J. A., Thorens, B., & Blázquez, E. (1996) · Journal of Neurochemistry

Regulation of Appetite and ObesityNeuropeptides and Animal Physiology

Cited by 194

Differences in Glucose Transporter Gene Expression between Rat Pancreatic α- and β-Cells Are Correlated to Differences in Glucose Transport but Not in Glucose Utilization

Heimberg, H., De Vos, A., Pipeleers, D., Thorens, B., & Schuit, F. (1995) · Journal of Biological Chemistry

Pancreatic function and diabetesMetabolism, Diabetes, and Cancer

Cited by 188

Gonadotropin-Releasing Hormone Secretion from Hypothalamic Neurons: Stimulation by Insulin and Potentiation by Leptin

Burcelin, R., Thorens, B., Glauser, M., Gaillard, R. C., & Pralong, F. P. (2003) · Endocrinology

Hypothalamic control of reproductive hormonesRegulation of Appetite and Obesity

Cited by 173

Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

Marquard, J., Otter, S., Welters, A., Stirban, A., Fischer, A., Eglinger, J., Herebian, D., Kletke, O., Klemen, M. S., Stožer, A., et al. (2015) · Nature Medicine

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 161

Chloroquine and ammonium chloride prevent terminal glycosylation of immunoglobulins in plasma cells without affecting secretion

Thorens, B., & Vassalli, P. (1986) · Nature

Cellular transport and secretionGlycosylation and Glycoproteins Research

Cited by 147

Neural regulation of pancreatic islet cell mass and function

Thorens, B. (2014) · Diabetes, Obesity and Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 140

Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization.

Burcelin, R., Dolci, W., & Thorens, B. (2000) · Diabetes

Pancreatic function and diabetesDiabetes Management and Research

Cited by 137

Hypoglycemia-Activated GLUT2 Neurons of the Nucleus Tractus Solitarius Stimulate Vagal Activity and Glucagon Secretion

Lamy, C. M., Sanno, H., Labouèbe, G., Picard, A., Magnan, C., Chatton, J.-Y., & Thorens, B. (2014) · Cell Metabolism

Pancreatic function and diabetesNeuroscience of respiration and sleep

Cited by 130

Carbohydrates and insulin resistance in clinical nutrition: Recommendations from the ESPEN expert group

Barazzoni, R., Deutz, N. E. P., Biolo, G., Bischoff, S., Boirie, Y., Cederholm, T., Cuerda, C., Delzenne, N., Leon Sanz, M., Ljungqvist, O., et al. (2017) · Clinical Nutrition

Hyperglycemia and glycemic control in critically ill and hospitalized patientsClinical Nutrition and Gastroenterology

Cited by 112

Increasing GLP-1–Induced β-Cell Proliferation by Silencing the Negative Regulators of Signaling cAMP Response Element Modulator-α and DUSP14

Klinger, S., Poussin, C., Debril, M.-B., Dolci, W., Halban, P. A., & Thorens, B. (2008) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 86

Glucose sensing and the pathogenesis of obesity and type 2 diabetes

Thorens, B. (2008) · International Journal of Obesity

Regulation of Appetite and ObesityPancreatic function and diabetes

Cited by 78

Gut-derived signaling molecules and vagal afferents in the control of glucose and energy homeostasis

Thorens, B., & Larsen, P. J. (2004) · Current Opinion in Clinical Nutrition and Metabolic Care

Regulation of Appetite and ObesityNeuropeptides and Animal Physiology

Cited by 73