Hampe, Jochen

Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease

Ott, S. J., Musfeldt, M., Wenderoth, D. F., Hampe, J., Brant, O., Fölsch, U. R., Timmis, K. N., & Schreiber, S. (2004) · Gut

Gut microbiota and healthInflammatory Bowel Disease

Cited by 1,311

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

Wahl, S., Drong, A., Lehne, B., Loh, M., Scott, W. R., Kunze, S., Tsai, P.-C., Ried, J. S., Zhang, W., Yang, Y., et al. (2017) · Nature

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 945

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

Buch, S., Stickel, F., Trépo, E., Way, M., Herrmann, A., Nischalke, H. D., Brosch, M., Rosendahl, J., Berg, T., Ridinger, M., et al. (2015) · Nature Genetics

Alcohol Consumption and Health EffectsGenetic Associations and Epidemiology

Cited by 565

Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease – novel insights into cellular communication circuits

Peiseler, M., Schwabe, R., Hampe, J., Kubes, P., Heikenwälder, M., & Tacke, F. (2022) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 564

Detection of Diverse Bacterial Signatures in Atherosclerotic Lesions of Patients With Coronary Heart Disease

Ott, S. J., El Mokhtari, N. E., Musfeldt, M., Hellmig, S., Freitag, S., Rehman, A., Kühbacher, T., Nikolaus, S., Namsolleck, P., Blaut, M., et al. (2006) · Circulation

Atherosclerosis and Cardiovascular DiseasesOral microbiology and periodontitis research

Cited by 391

Non-invasive stratification of hepatocellular carcinoma risk in non-alcoholic fatty liver using polygenic risk scores

Bianco, C., Jamialahmadi, O., Pelusi, S., Baselli, G., Dongiovanni, P., Zanoni, I., Santoro, L., Maier, S., Liguori, A., Meroni, M., et al. (2021) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentGenetic Associations and Epidemiology

Cited by 385

The ascending pathophysiology of cholestatic liver disease

Jansen, P. L. M., Ghallab, A., Vartak, N., Reif, R., Schaap, F. G., Hampe, J., & Hengstler, J. G. (2017) · Hepatology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 301

Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients

Teufel, A., Itzel, T., Erhart, W., Brosch, M., Wang, X. Y., Kim, Y. O., von Schönfels, W., Herrmann, A., Brückner, S., Stickel, F., et al. (2016) · Gastroenterology

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 229

Probiotic bacteria reduced duration and severity but not the incidence of common cold episodes in a double blind, randomized, controlled trial

de Vrese, M., Winkler, P., Rautenberg, P., Harder, T., Noah, C., Laue, C., Ott, S., Hampe, J., Schreiber, S., Heller, K., et al. (2006) · Vaccine

Probiotics and Fermented FoodsRespiratory viral infections research

Cited by 201

Hepatic stellate cells control liver zonation, size and functions via R-spondin 3

Sugimoto, A., Saito, Y., Wang, G., Sun, Q., Yin, C., Lee, K. H., Geng, Y., Rajbhandari, P., Hernandez, C., Steffani, M., et al. (2025) · Nature

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 133

Loss of hepatic Mboat7 leads to liver fibrosis

Thangapandi, V. R., Knittelfelder, O., Brosch, M., Patsenker, E., Vvedenskaya, O., Buch, S., Hinz, S., Hendricks, A., Nati, M., Herrmann, A., et al. (2021) · Gut

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 125

Three-Dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression

Segovia-Miranda, F., Morales-Navarrete, H., Kücken, M., Moser, V., Seifert, S., Repnik, U., Rost, F., Brosch, M., Hendricks, A., Hinz, S., et al. (2019) · Nature Medicine

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 109

Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control

Brosch, M., Kattler, K., Herrmann, A., von Schönfels, W., Nordström, K., Seehofer, D., Damm, G., Becker, T., Zeissig, S., Nehring, S., et al. (2018) · Nature Communications

Epigenetics and DNA MethylationLiver physiology and pathology

Cited by 98

Adipocyte-specific hypoxia-inducible factor 2α deficiency exacerbates obesity-induced brown adipose tissue dysfunction and metabolic dysregulation

García-Martín, R., Alexaki, V. I., Qin, N., Rubín de Celis, M. F., Economopoulou, M., Ziogas, A., Gercken, B., Kotlabova, K., Phieler, J., Ehrhart-Bornstein, M., et al. (2016) · Molecular and Cellular Biology

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 86

Anti-TNF-α antibodies improve intestinal barrier function in Crohn's disease

Noth, R., Stüber, E., Häsler, R., Nikolaus, S., Kühbacher, T., Hampe, J., Bewig, B., Schreiber, S., & Arlt, A. (2012) · Journal of Crohn s and Colitis

Inflammatory Bowel DiseaseRheumatoid Arthritis Research and Therapies

Cited by 68

Single-nucleotide polymorphisms in NAGNAG acceptors are highly predictive for variations of alternative splicing

Hiller, M., Huse, K., Szafranski, K., Jahn, N., Hampe, J., Schreiber, S., Backofen, R., & Platzer, M. (2006) · The American Journal of Human Genetics

RNA Research and SplicingGenetic Associations and Epidemiology

Cited by 54

A Mechanistic, Model‐Based Approach to Safety Assessment in Clinical Development

Lippert, J., Brosch, M., von Kampen, O., Meyer, M., Siegmund, H. ‐., Schafmayer, C., Becker, T., Laffert, B., Görlitz, L., Schreiber, S., et al. (2012) · CPT: Pharmacometrics & Systems Pharmacology

Statistical Methods in Clinical TrialsPharmaceutical studies and practices

Cited by 43

Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human

Kolbe, E., Aleithe, S., Rennert, C., Spormann, L., Ott, F., Meierhofer, D., Gajowski, R., Stöpel, C., Hoehme, S., Kücken, M., et al. (2019) · Cell Reports

Wnt/β-catenin signaling in development and cancerHedgehog Signaling Pathway Studies

Cited by 22