Turner, Jerrold R.

Intestinal mucosal barrier function in health and disease

Turner, J. R. (2009) · Nature reviews. Immunology

Gastrointestinal motility and disordersGut microbiota and health

Cited by 3,952

The intestinal epithelial barrier: a therapeutic target?

Odenwald, M. A., & Turner, J. R. (2017) · Nature Reviews Gastroenterology & Hepatology

Gastrointestinal motility and disordersBarrier Structure and Function Studies

Cited by 1,288

Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure

Shen, L., Black, E. D., Witkowski, E. D., Lencer, W. I., Guerriero, V., Schneeberger, E. E., & Turner, J. R. (2006) · Journal of Cell Science

Barrier Structure and Function StudiesIon Transport and Channel Regulation

Cited by 467

Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis

Su, L., Shen, L., Clayburgh, D. R., Nalle, S. C., Sullivan, E. A., Meddings, J. B., Abraham, C., & Turner, J. R. (2009) · Gastroenterology

Inflammatory Bowel DiseaseGut microbiota and health

Cited by 455

Hypoxia-Inducible Factor 1–Dependent Induction of Intestinal Trefoil Factor Protects Barrier Function during Hypoxia

Furuta, G. T., Turner, J. R., Taylor, C. T., Hershberg, R. M., Comerford, K., Narravula, S., Podolsky, D. K., & Colgan, S. P. (2001) · The Journal of Experimental Medicine

Barrier Structure and Function StudiesDigestive system and related health

Cited by 449

Intestinal Permeability Defects: Is It Time to Treat?

Odenwald, M. A., & Turner, J. R. (2013) · Clinical Gastroenterology and Hepatology

Gastrointestinal motility and disordersBarrier Structure and Function Studies

Cited by 366

Loss of intestinal core 1–derived O-glycans causes spontaneous colitis in mice

Fu, J., Wei, B., Wen, T., Johansson, M. E. V., Liu, X., Bradford, E., Thomsson, K. A., McGee, S., Mansour, L., Tong, M., et al. (2011) · Journal of Clinical Investigation

Glycosylation and Glycoproteins ResearchInflammatory Bowel Disease

Cited by 366

Myosin light chain kinase: pulling the strings of epithelial tight junction function

Cunningham, K. E., & Turner, J. R. (2012) · Annals of the New York Academy of Sciences

Barrier Structure and Function StudiesGastrointestinal motility and disorders

Cited by 345

Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: Summary of a symposium

Purohit, V., Bode, J. C., Bode, C., Brenner, D. A., Choudhry, M. A., Hamilton, F., Kang, Y. J., Keshavarzian, A., Rao, R., Sartor, R. B., et al. (2008) · Alcohol

Alcohol Consumption and Health EffectsGut microbiota and health

Cited by 325

Dysbiosis‐induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice

Chen, P., Stärkel, P., Turner, J. R., Ho, S. B., & Schnabl, B. (2015) · Hepatology

Alcohol Consumption and Health EffectsGut microbiota and health

Cited by 312

Hepatic Injury in Nonalcoholic Steatohepatitis Contributes to Altered Intestinal Permeability

Luther, J., Garber, J. J., Khalili, H., Dave, M., Bale, S. S., Jindal, R., Motola, D. L., Luther, S., Bohr, S., Jeoung, S. W., et al. (2015) · Cellular and Molecular Gastroenterology and Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 286

Dynorphin activates quorum sensing quinolone signaling in Pseudomonas aeruginosa

Zaborina, O., Lepine, F., Xiao, G., Valuckaite, V., Chen, Y., Li, T., Ciancio, M., Zaborin, A., Petroff, E., Turner, J. R., et al. (2007) · PLoS Pathogens

Bacterial biofilms and quorum sensingVibrio bacteria research studies

Cited by 207

The role of molecular remodeling in differential regulation of tight junction permeability

Turner, J. R., Buschmann, M. M., Romero-Calvo, I., Sailer, A., & Shen, L. (2014) · Seminars in Cell & Developmental Biology

Barrier Structure and Function StudiesGastrointestinal motility and disorders

Cited by 200

Helicobacter pylori Dysregulation of Gastric Epithelial Tight Junctions by Urease-Mediated Myosin II Activation

Wroblewski, L. E., Shen, L., Ogden, S., Romero–Gallo, J., Lapierre, L. A., Israel, D. A., Turner, J. R., & Peek, R. M. (2009) · Gastroenterology

Helicobacter pylori-related gastroenterology studiesGastrointestinal motility and disorders

Cited by 193

Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux

Buschmann, M. M., Shen, L., Rajapakse, H., Raleigh, D. R., Wang, Y., Wang, Y., Lingaraju, A., Zha, J., Abbott, E., McAuley, E. M., et al. (2013) · Molecular Biology of the Cell

Barrier Structure and Function StudiesCell Adhesion Molecules Research

Cited by 192

Tight junctions as targets and effectors of mucosal immune homeostasis

Zuo, L., Kuo, W.-T., & Turner, J. R. (2020) · Cellular and Molecular Gastroenterology and Hepatology

Barrier Structure and Function StudiesGastrointestinal motility and disorders

Cited by 191

Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis

Graham, W. V., He, W., Marchiando, A. M., Zha, J., Singh, G., Li, H.-S., Biswas, A., Ong, M. L. D. M., Jiang, Z.-H., Choi, W., et al. (2019) · Nature Medicine

Inflammatory Bowel DiseaseGastrointestinal motility and disorders

Cited by 176

Distinct and Synergistic Contributions of Epithelial Stress and Adaptive Immunity to Functions of Intraepithelial Killer Cells and Active Celiac Disease

Setty, M., Discepolo, V., Abadie, V., Kamhawi, S., Mayassi, T., Kent, A., Ciszewski, C., Maglio, M., Kistner, E., Bhagat, G., et al. (2015) · Gastroenterology

Celiac Disease Research and ManagementWheat and Barley Genetics and Pathology

Cited by 119

The epithelial-specific ER stress sensor ERN2/IRE1β enables host-microbiota crosstalk to affect colon goblet cell development

Grey, M. J., De Luca, H., Ward, D. V., Kreulen, I. A. M., Bugda Gwilt, K., Foley, S. E., Thiagarajah, J. R., McCormick, B. A., Turner, J. R., & Lencer, W. I. (2022) · Journal of Clinical Investigation

Endoplasmic Reticulum Stress and DiseaseGut microbiota and health

Cited by 65

Retinoic Acid-induced Gene-1 (RIG-I) Associates with the Actin Cytoskeleton via Caspase Activation and Recruitment Domain-dependent Interactions

Mukherjee, A., Morosky, S. A., Shen, L., Weber, C. R., Turner, J. R., Kim, K. S., Wang, T., & Coyne, C. B. (2009) · Journal of Biological Chemistry

interferon and immune responsesImmune Response and Inflammation

Cited by 62

cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity

Tse, C.-M., Yin, J., Singh, V., Sarker, R., Lin, R., Verkman, A. S., Turner, J. R., & Donowitz, M. (2019) · Cellular and Molecular Gastroenterology and Hepatology

Ion Transport and Channel RegulationCystic Fibrosis Research Advances

Cited by 53

Constipation-Predominant Irritable Bowel Syndrome Females Have Normal Colonic Barrier and Secretory Function

Peters, S. A., Edogawa, S., Sundt, W. J., Dyer, R. B., Dalenberg, D. A., Mazzone, A., Singh, R. J., Moses, N., Smyrk, T. C., Weber, C., et al. (2017) · American Journal of Gastroenterology

Gastrointestinal motility and disordersGut microbiota and health

Cited by 48