Krueger, James G.

Progressive activation of TH2/TH22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis

Gittler, J. K., Shemer, A., Suárez-Fariñas, M., Fuentes-Duculan, J., Gulewicz, K. J., Wang, C. Q. F., Mitsui, H., Cardinale, I., de Guzman Strong, C., Krueger, J. G., et al. (2012) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 981

Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis

Chiricozzi, A., Guttman-Yassky, E., Suárez-Fariñas, M., Nograles, K. E., Tian, S., Cardinale, I., Chimenti, S., & Krueger, J. G. (2011) · Journal of Investigative Dermatology

Psoriasis: Treatment and PathogenesisDermatology and Skin Diseases

Cited by 686

The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization

Noda, S., Suárez-Fariñas, M., Ungar, B., Kim, S. J., de Guzman Strong, C., Xu, H., Peng, X., Estrada, Y. D., Nakajima, S., Honda, T., et al. (2015) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 657

IL-22–producing “T22” T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17–producing TH17 T cells

Nograles, K. E., Zaba, L. C., Shemer, A., Fuentes-Duculan, J., Cardinale, I., Kikuchi, T., Ramon, M., Bergman, R., Krueger, J. G., & Guttman-Yassky, E. (2009) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 627

Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitis

Suárez-Fariñas, M., Dhingra, N., Gittler, J., Shemer, A., Cardinale, I., de Guzman Strong, C., Krueger, J. G., & Guttman-Yassky, E. (2013) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 483

Early-onset pediatric atopic dermatitis is TH2 but also TH17 polarized in skin

Esaki, H., Brunner, P. M., Renert-Yuval, Y., Czarnowicki, T., Huynh, T., Tran, G., Lyon, S., Rodriguez, G., Immaneni, S., Johnson, D. B., et al. (2016) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 428

Efficacy and safety of fezakinumab (an IL-22 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by conventional treatments: A randomized, double-blind, phase 2a trial

Guttman-Yassky, E., Brunner, P. M., Neumann, A. U., Khattri, S., Pavel, A. B., Malik, K., Singer, G. K., Baum, D., Gilleaudeau, P., Sullivan-Whalen, M., et al. (2018) · Journal of the American Academy of Dermatology

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 343

Molecular profiling of contact dermatitis skin identifies allergen-dependent differences in immune response

Dhingra, N., Shemer, A., Correa da Rosa, J., Rozenblit, M., Fuentes-Duculan, J., Gittler, J. K., Finney, R., Czarnowicki, T., Zheng, X., Xu, H., et al. (2014) · Journal of Allergy and Clinical Immunology

Contact Dermatitis and AllergiesDermatology and Skin Diseases

Cited by 305

312-nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions

Ozawa, M., Ferenczi, K., Kikuchi, T., Cardinale, I., Austin, L. M., Coven, T. R., Burack, L. H., & Krueger, J. G. (1999) · The Journal of Experimental Medicine

Psoriasis: Treatment and PathogenesisDermatology and Skin Diseases

Cited by 298

Broad defects in epidermal cornification in atopic dermatitis identified through genomic analysis

Guttman-Yassky, E., Suárez-Fariñas, M., Chiricozzi, A., Nograles, K. E., Shemer, A., Fuentes-Duculan, J., Cardinale, I., Lin, P., Bergman, R., Bowcock, A. M., et al. (2009) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 268

TNF-α Downregulates Filaggrin and Loricrin through c-Jun N-terminal Kinase: Role for TNF-α Antagonists to Improve Skin Barrier

Kim, B. E., Howell, M. D., Guttman, E., Gilleaudeau, P. M., Cardinale, I. R., Boguniewicz, M., Krueger, J. G., & Leung, D. Y. M. (2011) · Journal of Investigative Dermatology

Psoriasis: Treatment and PathogenesisDermatology and Skin Diseases

Cited by 239

The aging skin microenvironment dictates stem cell behavior

Ge, Y., Miao, Y., Gur-Cohen, S., Gomez, N., Yang, H., Nikolova, M., Polak, L., Hu, Y., Verma, A., Elemento, O., et al. (2020) · Proceedings of the National Academy of Sciences

Hair Growth and DisordersHematopoietic Stem Cell Transplantation

Cited by 190

The molecular features of normal and atopic dermatitis skin in infants, children, adolescents, and adults

Renert-Yuval, Y., Del Duca, E., Pavel, A. B., Fang, M., Lefferdink, R., Wu, J., Diaz, A., Estrada, Y. D., Canter, T., Zhang, N., et al. (2021) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 168

Petrolatum: Barrier repair and antimicrobial responses underlying this “inert” moisturizer

Czarnowicki, T., Malajian, D., Khattri, S., Correa da Rosa, J., Dutt, R., Finney, R., Dhingra, N., Xiangyu, P., Xu, H., Estrada, Y. D., et al. (2016) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesContact Dermatitis and Allergies

Cited by 161

Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques

Johnson-Huang, L. M., Suárez-Fariñas, M., Sullivan-Whalen, M., Gilleaudeau, P., Krueger, J. G., & Lowes, M. A. (2010) · Journal of Investigative Dermatology

Psoriasis: Treatment and PathogenesisDermatology and Skin Diseases

Cited by 160

Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections

Crequer, A., Troeger, A., Patin, E., Ma, C. S., Picard, C., Pedergnana, V., Fieschi, C., Lim, A., Abhyankar, A., Gineau, L., et al. (2012) · Journal of Clinical Investigation

Immunodeficiency and Autoimmune DisordersT-cell and B-cell Immunology

Cited by 159

Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis

Zhou, L., Leonard, A., Pavel, A. B., Malik, K., Raja, A., Glickman, J., Estrada, Y. D., Peng, X., del Duca, E., Sanz-Cabanillas, J., et al. (2019) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesAsthma and respiratory diseases

Cited by 146

Evolution of pathologic T-cell subsets in patients with atopic dermatitis from infancy to adulthood

Czarnowicki, T., He, H., Canter, T., Han, J., Lefferdink, R., Erickson, T., Rangel, S., Kameyama, N., Kim, H. J., Pavel, A. B., et al. (2020) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesAsthma and respiratory diseases

Cited by 118

The characterization of varicella zoster virus-specific T cells in skin and blood during aging

Vukmanovic-Stejic, M., Sandhu, D., Seidel, J. A., Patel, N., Sobande, T. O., Agius, E., Jackson, S. E., Fuentes-Duculan, J., Suárez-Fariñas, M., Mabbott, N. A., et al. (2015) · Journal of Investigative Dermatology

Herpesvirus Infections and TreatmentsT-cell and B-cell Immunology

Cited by 117

Atopic dermatitis in Chinese patients shows TH2/TH17 skewing with psoriasiform features

Chan, T. C., Sanyal, R. D., Pavel, A. B., Glickman, J., Zheng, X., Xu, H., Cho, Y.-T., Tsai, T.-F., Wen, H.-C., Peng, X., et al. (2018) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

Cited by 114

The blood proteomic signature of early-onset pediatric atopic dermatitis shows systemic inflammation and is distinct from adult long-standing disease

Brunner, P. M., He, H., Pavel, A. B., Czarnowicki, T., Lefferdink, R., Erickson, T., Canter, T., Puar, N., Rangel, S. M., Malik, K., et al. (2019) · Journal of the American Academy of Dermatology

Dermatology and Skin DiseasesAsthma and respiratory diseases

Cited by 109

Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase-induced inflammation

Vukmanovic-Stejic, M., Chambers, E. S., Suárez-Fariñas, M., Sandhu, D., Fuentes-Duculan, J., Patel, N., Agius, E., Lacy, K. E., Turner, C. T., Larbi, A., et al. (2018) · Journal of Allergy and Clinical Immunology

Herpesvirus Infections and TreatmentsT-cell and B-cell Immunology

Cited by 103

Narrowband (312-nm) UV-B Suppresses Interferon γ and Interleukin (IL) 12 and Increases IL-4 Transcripts: Differential Regulation of Cytokines at the Single-Cell Level

Walters, I. B., Ozawa, M., Cardinale, I., Gilleaudeau, P., Trepicchio, W. L., Bliss, J., & Krueger, J. G. (2003) · Archives of Dermatology

Psoriasis: Treatment and PathogenesisDermatology and Skin Diseases

Cited by 83

Cell-adhesion-disrupting action of interleukin 6 in human ductal breast carcinoma cells.

Tamm, I., Kikuchi, T., Cardinale, I., & Krueger, J. G. (1994) · Proceedings of the National Academy of Sciences

Cytokine Signaling Pathways and InteractionsCell Adhesion Molecules Research

Cited by 47