Frautschy, Sally A.

Neuroinflammation in Alzheimer's disease

Heneka, M. T., Carson, M. J., Khoury, J. E., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., et al. (2015) · The Lancet Neurology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 6,226

Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo

Yang, F., Lim, G. P., Begum, A. N., Ubeda, O. J., Simmons, M. R., Ambegaokar, S. S., Chen, P. P., Kayed, R., Glabe, C. G., Frautschy, S. A., et al. (2005) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsCurcumin's Biomedical Applications

Cited by 2,336

The Curry Spice Curcumin Reduces Oxidative Damage and Amyloid Pathology in an Alzheimer Transgenic Mouse

Lim, G. P., Chu, T., Yang, F., Beech, W., Frautschy, S. A., & Cole, G. M. (2001) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsCurcumin's Biomedical Applications

Cited by 1,530

Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model

Calon, F., Lim, G. P., Yang, F., Morihara, T., Teter, B., Ubeda, O., Rostaing, P., Triller, A., Salem, N., Ashe, K. H., et al. (2004) · Neuron

Fatty Acid Research and HealthAlzheimer's disease research and treatments

Cited by 707

Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer’s Disease

Begum, A. N., Jones, M. R., Lim, G. P., Morihara, T., Kim, P., Heath, D. D., Rock, C. L., Pruitt, M. A., Yang, F., Hudspeth, B., et al. (2008) · The Journal of Pharmacology and Experimental Therapeutics

Curcumin's Biomedical ApplicationsAlzheimer's disease research and treatments

Cited by 604

-Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin

Ma, Q.-L., Yang, F., Rosario, E. R., Ubeda, O. J., Beech, W., Gant, D. J., Chen, P. P., Hudspeth, B., Chen, C., Zhao, Y., et al. (2009) · Journal of Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 536

Neuroprotective effects of curcumin

Cole, G. M., Teter, B., & Frautschy, S. A. (2007) · ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY

Curcumin's Biomedical ApplicationsAlzheimer's disease research and treatments

Cited by 516

Phenolic anti-inflammatory antioxidant reversal of Aβ-induced cognitive deficits and neuropathology

Frautschy, S. (2001) · Neurobiology of Aging

Curcumin's Biomedical ApplicationsAlzheimer's disease research and treatments

Cited by 514

Insulin-degrading Enzyme as a Downstream Target of Insulin Receptor Signaling cascade: Implications for Alzheimer's Disease Intervention

Zhao, L., Teter, B., Morihara, T., Lim, G. P., Ambegaokar, S. S., Ubeda, O. J., Frautschy, S. A., & Cole, G. M. (2004) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 329

Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease

Zhao, L., Ma, Q.-L., Calon, F., Harris-White, M. E., Yang, F., Lim, G. P., Morihara, T., Ubeda, O. J., Ambegaokar, S., Hansen, J. E., et al. (2006) · Nature Neuroscience

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 317

Effects of injected Alzheimer beta-amyloid cores in rat brain.

Frautschy, S. A., Baird, A., & Cole, G. M. (1991) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 254

Clinical development of curcumin in neurodegenerative disease

Hu, S., Maiti, P., Ma, Q., Zuo, X., Jones, M. R., Cole, G. M., & Frautschy, S. A. (2015) · Expert Review of Neurotherapeutics

Curcumin's Biomedical ApplicationsAlzheimer's disease research and treatments

Cited by 179

NSAID and Antioxidant Prevention of Alzheimer's Disease: Lessons from In Vitro and Animal Models

COLE, G. M., MORIHARA, T., LIM, G. P., YANG, F., BEGUM, A., & FRAUTSCHY, S. A. (2004) · Annals of the New York Academy of Sciences

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 129

Antibodies against β‐amyloid reduce aβ oligomers, glycogen synthase kinase‐3β activation and τ phosphorylation in vivo and in vitro

Ma, Q., Lim, G. P., Harris‐White, M. E., Yang, F., Ambegaokar, S. S., Ubeda, O. J., Glabe, C. G., Teter, B., Frautschy, S. A., & Cole, G. M. (2006) · Journal of Neuroscience Research

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 126

Curcumin Ameliorates Neuroinflammation, Neurodegeneration, and Memory Deficits in p25 Transgenic Mouse Model that Bears Hallmarks of Alzheimer’s Disease

Sundaram, J. R., Poore, C. P., Sulaimee, N. H. B., Pareek, T., Cheong, W. F., Wenk, M. R., Pant, H. C., Frautschy, S. A., Low, C.-M., & Kesavapany, S. (2017) · Journal of Alzheimer s Disease

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 105

Exercise can increase small heat shock proteins (sHSP) and pre- and post-synaptic proteins in the hippocampus

Hu, S., Ying, Z., Gomez-Pinilla, F., & Frautschy, S. A. (2009) · Brain Research

Heat shock proteins researchNeuroscience and Neuropharmacology Research

Cited by 79

Protease inhibitor coinfusion with amyloid β-protein results in enhanced deposition and toxicity in rat brain

Frautschy, S. A., Horn, D. L., Sigel, J. J., Harris-White, M. E., Mendoza, J. J., Yang, F., Saido, T. C., & Cole, G. M. (1998) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 65

Apolipoprotein J (clusterin) activates rodent microglia in vivo and in vitro

Xie, Z., Harris‐White, M. E., Wals, P. A., Frautschy, S. A., Finch, C. E., & Morgan, T. E. (2005) · Journal of Neurochemistry

Neuroinflammation and Neurodegeneration MechanismsClusterin in disease pathology

Cited by 53