Heap, John T.

The ClosTron: a universal gene knock-out system for the genus Clostridium

Heap, J. T., Pennington, O. J., Cartman, S. T., Carter, G. P., & Minton, N. P. (2007) · Journal of Microbiological Methods

Bacterial Genetics and BiotechnologyCRISPR and Genetic Engineering

Cited by 663

A modular system for Clostridium shuttle plasmids

Heap, J. T., Pennington, O. J., Cartman, S. T., & Minton, N. P. (2009) · Journal of Microbiological Methods

Bacterial Genetics and BiotechnologyMicrobial Metabolic Engineering and Bioproduction

Cited by 489

The ClosTron: mutagenesis in Clostridium refined and streamlined

Heap, J. T., Kuehne, S. A., Ehsaan, M., Cartman, S. T., Cooksley, C. M., Scott, J. C., & Minton, N. P. (2010) · Journal of Microbiological Methods

CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology

Cited by 418

Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker

Heap, J. T., Ehsaan, M., Cooksley, C. M., Ng, Y.-K., Cartman, S. T., Winzer, K., & Minton, N. P. (2012) · Nucleic Acids Research

Microbial Metabolic Engineering and BioproductionBacterial Genetics and Biotechnology

Cited by 201

Start-Stop Assembly: a functionally scarless DNA assembly system optimized for metabolic engineering

Taylor, G. M., Mordaka, P. M., & Heap, J. T. (2019) · Nucleic Acids Research

Microbial Metabolic Engineering and BioproductionCRISPR and Genetic Engineering

Cited by 91

A Rhamnose-Inducible System for Precise and Temporal Control of Gene Expression in Cyanobacteria

Kelly, C. L., Taylor, G. M., Hitchcock, A., Torres-Méndez, A., & Heap, J. T. (2018) · ACS Synthetic Biology

Bacterial Genetics and BiotechnologyMicrobial Metabolic Engineering and Bioproduction

Cited by 80

Combinatorial assembly platform enabling engineering of genetically stable metabolic pathways in cyanobacteria

Taylor, G. M., Hitchcock, A., & Heap, J. T. (2021) · Nucleic Acids Research

Microbial Metabolic Engineering and BioproductionPlant biochemistry and biosynthesis

Cited by 38

Transcriptional terminators allow leak-free chromosomal integration of genetic constructs in cyanobacteria

Kelly, C. L., Taylor, G. M., Satkute, A., Dekker, L., & Heap, J. T. (2019) · Microorganisms

Microbial Metabolic Engineering and BioproductionBacterial Genetics and Biotechnology

Cited by 29