Hingorani, Aroon D.

Selecting instruments for Mendelian randomization in the wake of genome-wide association studies.

Swerdlow, D. I., Kuchenbaecker, K. B., Shah, S., Sofat, R., Holmes, M. V., White, J., Mindell, J. S., Kivimaki, M., Brunner, E. J., Whittaker, J. C., et al. (2016) · International Journal of Epidemiology

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 387

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

Schmidt, A. F., Swerdlow, D. I., Holmes, M. V., Patel, R. S., Fairhurst-Hunter, Z., Lyall, D. M., Hartwig, F. P., Horta, B. L., Hyppönen, E., Power, C., et al. (2017) · The Lancet Diabetes & Endocrinology

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 380

Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis

Dale, C. E., Fatemifar, G., Palmer, T. M., White, J., Prieto-Merino, D., Zabaneh, D., Engmann, J. E. L., Shah, T., Wong, A., Warren, H. R., et al. (2017) · Circulation

Genetic Associations and EpidemiologyCardiovascular Disease and Adiposity

Cited by 345

Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose

Reynolds, C. J., Pade, C., Gibbons, J. M., Butler, D. K., Otter, A. D., Menacho, K., Fontana, M., Smit, A., Sackville-West, J. E., Cutino-Moguel, T., et al. (2021) · Science

SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations

Cited by 338

Genetic evidence of assortative mating in humans

Robinson, M. R., Kleinman, A., Graff, M., Vinkhuyzen, A. A. E., Couper, D., Miller, M. B., Peyrot, W. J., Abdellaoui, A., Zietsch, B. P., Nolte, I. M., et al. (2017) · Nature Human Behaviour

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 326

A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service

Kuan, V., Denaxas, S., Gonzalez-Izquierdo, A., Direk, K., Bhatti, O., Husain, S., Sutaria, S., Hingorani, M., Nitsch, D., Parisinos, C. A., et al. (2019) · The Lancet Digital Health

Chronic Disease Management StrategiesMedical Coding and Health Information

Cited by 305

Association of Lipid Fractions With Risks for Coronary Artery Disease and Diabetes

White, J., Swerdlow, D. I., Preiss, D., Fairhurst-Hunter, Z., Keating, B. J., Asselbergs, F. W., Sattar, N., Humphries, S. E., Hingorani, A. D., & Holmes, M. V. (2016) · JAMA Cardiology

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 293

Synergistic insights into human health from aptamer- and antibody-based proteomic profiling

Pietzner, M., Wheeler, E., Carrasco-Zanini, J., Kerrison, N. D., Oerton, E., Koprulu, M., Luan, J., Hingorani, A. D., Williams, S. A., Wareham, N. J., et al. (2021) · Nature Communications

Genetic Associations and EpidemiologyAdvanced Biosensing Techniques and Applications

Cited by 234

Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis

Holmes, M. V., Lange, L. A., Palmer, T., Lanktree, M. B., North, K. E., Almoguera, B., Buxbaum, S., Chandrupatla, H. R., Elbers, C. C., Guo, Y., et al. (2014) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 216

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase

Würtz, P., Wang, Q., Soininen, P., Kangas, A. J., Fatemifar, G., Tynkkynen, T., Tiainen, M., Perola, M., Tillin, T., Hughes, A. D., et al. (2016) · Journal of the American College of Cardiology

Lipoproteins and Cardiovascular HealthMetabolomics and Mass Spectrometry Studies

Cited by 188

Association between periodontal disease and its treatment, flow-mediated dilatation and carotid intima-media thickness: a systematic review and meta-analysis

Orlandi, M., Suvan, J., Petrie, A., Donos, N., Masi, S., Hingorani, A., Deanfield, J., & D’Aiuto, F. (2014) · Atherosclerosis

Oral microbiology and periodontitis researchCardiovascular Health and Disease Prevention

Cited by 164

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., et al. (2017) · Nature Communications

Genetic Associations and EpidemiologyGenetics, Aging, and Longevity in Model Organisms

Cited by 161

Lipid lowering and Alzheimer disease risk: A mendelian randomization study

Williams, D. M., Finan, C., Schmidt, A. F., Burgess, S., & Hingorani, A. D. (2020) · Annals of Neurology

Lipoproteins and Cardiovascular HealthAlzheimer's disease research and treatments

Cited by 157

Evidence of association of APOE with age-related macular degeneration - a pooled analysis of 15 studies

McKay, G. J., Patterson, C. C., Chakravarthy, U., Dasari, S., Klaver, C. C., Vingerling, J. R., Ho, L., de Jong, P. T. V. M., Fletcher, A. E., Young, I. S., et al. (2011) · Human Mutation

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 151

Unraveling the directional link between adiposity and inflammation: A bidirectional Mendelian randomization approach

Welsh, P., Polisecki, E., Robertson, M., Jahn, S., Buckley, B. M., de Craen, A. J. M., Ford, I., Jukema, J. W., Macfarlane, P. W., Packard, C. J., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism

Adipokines, Inflammation, and Metabolic DiseasesGenetic Associations and Epidemiology

Cited by 140

Is periodontal inflammation associated with raised blood pressure? Evidence from a National US survey

Tsakos, G., Sabbah, W., Hingorani, A. D., Netuveli, G., Donos, N., Watt, R. G., & D'Aiuto, F. (2010) · Journal of Hypertension

Oral microbiology and periodontitis researchBlood Pressure and Hypertension Studies

Cited by 134

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.

White, J., Sofat, R., Hemani, G., Shah, T., Engmann, J., Dale, C., Shah, S., Kruger, F. A., Giambartolomei, C., Swerdlow, D. I., et al. (2016) · The Lancet Diabetes & Endocrinology

Gout, Hyperuricemia, Uric AcidGenetic Associations and Epidemiology

Cited by 132

PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease

Schmidt, A. F., Carter, J.-P. L., Pearce, L. S., Wilkins, J. T., Overington, J. P., Hingorani, A. D., & Casas, J. (2020) · Cochrane Database of Systematic Reviews

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 123

Adjustment for index event bias in genome-wide association studies of subsequent events.

Dudbridge, F., Allen, R. J., Sheehan, N. A., Schmidt, A. F., Lee, J. C., Jenkins, R. G., Wain, L. V., Hingorani, A. D., & Patel, R. S. (2019) · Nature Communications

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 115

Variations in Apolipoprotein E Frequency With Age in a Pooled Analysis of a Large Group of Older People

McKay, G. J., Silvestri, G., Chakravarthy, U., Dasari, S., Fritsche, L. G., Weber, B. H., Keilhauer, C. N., Klein, M. L., Francis, P. J., Klaver, C. C., et al. (2011) · American Journal of Epidemiology

Lipoproteins and Cardiovascular HealthRetinal Diseases and Treatments

Cited by 105

Separating the Mechanism-Based and Off-Target Actions of Cholesteryl Ester Transfer Protein Inhibitors With CETP Gene Polymorphisms

Sofat, R., Hingorani, A. D., Smeeth, L., Humphries, S. E., Talmud, P. J., Cooper, J., Shah, T., Sandhu, M. S., Ricketts, S. L., Boekholdt, S. M., et al. (2010) · Circulation

Lipoproteins and Cardiovascular HealthParaoxonase enzyme and polymorphisms

Cited by 104

Adipose and Height Growth Through Childhood and Blood Pressure Status in a Large Prospective Cohort Study

Jones, A., Charakida, M., Falaschetti, E., Hingorani, A. D., Finer, N., Masi, S., Donald, A. E., Lawlor, D. A., Davey Smith, G., & Deanfield, J. E. (2012) · Hypertension

Birth, Development, and HealthBlood Pressure and Hypertension Studies

Cited by 93

Plasma proteins, cognitive decline, and 20-year risk of dementia in the Whitehall II and Atherosclerosis Risk in Communities studies

Lindbohm, J. V., Mars, N., Walker, K. A., Singh‐Manoux, A., Livingston, G., Brunner, E. J., Sipilä, P. N., Saksela, K., Ferrie, J. E., Lovering, R. C., et al. (2022) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 70

Joint Genetic Inhibition of PCSK9 and CETP and the Association With Coronary Artery Disease: A Factorial Mendelian Randomization Study

Cupido, A. J., Reeskamp, L. F., Hingorani, A. D., Finan, C., Asselbergs, F. W., Hovingh, G. K., & Schmidt, A. F. (2022) · JAMA Cardiology

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 68