Zipp, Frauke

Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

International Multiple Sclerosis Genetics Consortium, Patsopoulos, N. A., Baranzini, S. E., Santaniello, A., Shoostari, P., Cotsapas, C., Wong, G., Beecham, A. H., James, T., Replogle, J., et al. (2019) · Science

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 1,471

Multiple Sclerosis Severity Score: Using disability and disease duration to rate disease severity

Roxburgh, R. H. S. R., Seaman, S. R., Masterman, T., Hensiek, A. E., Sawcer, S. J., Vukusic, S., Achiti, I., Confavreux, C., Coustans, M., le Page, E., et al. (2005) · Neurology

Multiple Sclerosis Research StudiesHealth Systems, Economic Evaluations, Quality of Life

Cited by 963

Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System

Bruttger, J., Karram, K., Wörtge, S., Regen, T., Marini, F., Hoppmann, N., Klein, M., Blank, T., Yona, S., Wolf, Y., et al. (2015) · Immunity

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 634

Sirt1 contributes critically to the redox-dependent fate of neural progenitors

Prozorovski, T., Schulze-Topphoff, U., Glumm, R., Baumgart, J., Schröter, F., Ninnemann, O., Siegert, E., Bendix, I., Brüstle, O., Nitsch, R., et al. (2008) · Nature Cell Biology

Neurogenesis and neuroplasticity mechanismsSirtuins and Resveratrol in Medicine

Cited by 451

In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis

Siffrin, V., Radbruch, H., Glumm, R., Niesner, R., Paterka, M., Herz, J., Leuenberger, T., Lehmann, S. M., Luenstedt, S., Rinnenthal, J. L., et al. (2010) · Immunity

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 325

Microglia–blood vessel interactions: a double-edged sword in brain pathologies

Dudvarski Stankovic, N., Teodorczyk, M., Ploen, R., Zipp, F., & Schmidt, M. H. H. (2016) · Acta Neuropathologica

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 301

Neuronal damage in brain inflammation

Aktas, O., Ullrich, O., Infante-Duarte, C., Nitsch, R., & Zipp, F. (2007) · Archives of Neurology

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 249

Perivascular spaces—MRI marker of inflammatory activity in the brain?

Wuerfel, J., Haertle, M., Waiczies, H., Tysiak, E., Bechmann, I., Wernecke, K. D., Zipp, F., & Paul, F. (2008) · Brain

Multiple Sclerosis Research StudiesCerebrospinal fluid and hydrocephalus

Cited by 244

Locus for severity implicates CNS resilience in progression of multiple sclerosis

International Multiple Sclerosis Genetics Consortium, Harroud, A., Stridh, P., McCauley, J. L., Saarela, J., van den Bosch, A. M. R., Engelenburg, H. J., Beecham, A. H., Alfredsson, L., Alikhani, K., et al. (2023) · Nature

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 243

Understanding the Role of T Cells in CNS Homeostasis

Ellwardt, E., Walsh, J. T., Kipnis, J., & Zipp, F. (2016) · Trends in Immunology

Neuroinflammation and Neurodegeneration MechanismsT-cell and B-cell Immunology

Cited by 156

Activation of Microglial Poly(ADP-Ribose)-Polymerase-1 by Cholesterol Breakdown Products during Neuroinflammation

Diestel, A., Aktas, O., Hackel, D., Häke, I., Meier, S., Raine, C. S., Nitsch, R., Zipp, F., & Ullrich, O. (2003) · The Journal of Experimental Medicine

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 155

Graph theoretical framework of brain networks in multiple sclerosis: a review of concepts

Fleischer, V., Radetz, A., Ciolac, D., Muthuraman, M., Gonzalez-Escamilla, G., Zipp, F., & Groppa, S. (2019) · Neuroscience

Functional Brain Connectivity StudiesMultiple Sclerosis Research Studies

Cited by 151

Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system

Schulze-Topphoff, U., Prat, A., Prozorovski, T., Siffrin, V., Paterka, M., Herz, J., Bendix, I., Ifergan, I., Schadock, I., Mori, M. A., et al. (2009) · Nature Medicine

Multiple Sclerosis Research StudiesCoagulation, Bradykinin, Polyphosphates, and Angioedema

Cited by 131

BLBP-expression in astrocytes during experimental demyelination and in human multiple sclerosis lesions

Kipp, M., Gingele, S., Pott, F., Clarner, T., van der Valk, P., Denecke, B., Gan, L., Siffrin, V., Zipp, F., Dreher, W., et al. (2011) · Brain, Behavior, and Immunity

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 83

Characterizing Microstructural Tissue Properties in Multiple Sclerosis with Diffusion MRI at 7 T and 3 T: The Impact of the Experimental Design

De Santis, S., Bastiani, M., Droby, A., Kolber, P., Zipp, F., Pracht, E., Stoecker, T., Groppa, S., & Roebroeck, A. (2019) · Neuroscience

Advanced Neuroimaging Techniques and ApplicationsMultiple Sclerosis Research Studies

Cited by 56

Prognostic factors for multiple sclerosis symptoms in radiologically isolated syndrome

Fissolo, N., Schaedelin, S., Villar, L. M., Lünemann, J. D., Correale, J., Rejdak, K., Schwab, N., Vilaseca, A., Held, F., García-Merino, A., et al. (2025) · JAMA Neurology

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 27

Diagnosis of multiple sclerosis: a multicentre study to compare revised McDonald-2010 and Filippi-2010 criteria

Preziosa, P., Rocca, M. A., Mesaros, S., Meani, A., Montalban, X., Drulovic, J., Droby, A., Zipp, F., Calabrese, M., Sastre-Garriga, J., et al. (2018) · Journal of Neurology, Neurosurgery & Psychiatry

Multiple Sclerosis Research StudiesClinical Reasoning and Diagnostic Skills

Cited by 26