Mattson, Mark P.

Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession

Liu, D., Pitta, M., Jiang, H., Lee, J.-H., Zhang, G., Chen, X., Kawamoto, E. M., & Mattson, M. P. (2013) · Neurobiology of Aging

Alzheimer's disease research and treatmentsAutophagy in Disease and Therapy

Cited by 238

Central Mechanisms of HPA Axis Regulation by Voluntary Exercise

Stranahan, A. M., Lee, K., & Mattson, M. P. (2008) · NeuroMolecular Medicine

Stress Responses and CortisolRegulation of Appetite and Obesity

Cited by 235

Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal

Tang, S.-C., Lathia, J. D., Selvaraj, P. K., Jo, D.-G., Mughal, M. R., Cheng, A., Siler, D. A., Markesbery, W. R., Arumugam, T. V., & Mattson, M. P. (2008) · Experimental Neurology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 232

Roles of lipid peroxidation in modulation of cellular signaling pathways, cell dysfunction, and death in the nervous system

Keller, J. N., & Mattson, M. P. (1998) · Reviews in the Neurosciences

Antioxidant Activity and Oxidative StressRedox biology and oxidative stress

Cited by 217

Posteromedial cortex glutamate and GABA predict intrinsic functional connectivity of the default mode network

Kapogiannis, D., Reiter, D. A., Willette, A. A., & Mattson, M. P. (2013) · NeuroImage

Functional Brain Connectivity StudiesAdvanced MRI Techniques and Applications

Cited by 211

Intermittent fasting attenuates lipopolysaccharide-induced neuroinflammation and memory impairment.

Vasconcelos, A. R., Yshii, L. M., Viel, T. A., Buck, H. S., Mattson, M. P., Scavone, C., & Kawamoto, E. M. (2014) · Journal of Neuroinflammation

Dietary Effects on HealthNeuroinflammation and Neurodegeneration Mechanisms

Cited by 210

NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer’s models

Bahn, G., Park, J.-S., Yun, U. J., Lee, Y. J., Choi, Y., Park, J. S., Baek, S. H., Choi, B. Y., Cho, Y. S., Kim, H. K., et al. (2019) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsGenomics, phytochemicals, and oxidative stress

Cited by 210

Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess

Martin, B., Pearson, M., Kebejian, L., Golden, E., Keselman, A., Bender, M., Carlson, O., Egan, J., Ladenheim, B., Cadet, J.-L., et al. (2007) · Endocrinology

Regulation of Appetite and ObesityDietary Effects on Health

Cited by 199

Selective Vulnerability of Neurons in Layer II of the Entorhinal Cortex during Aging and Alzheimer's Disease

Stranahan, A. M., & Mattson, M. P. (2010) · Neural Plasticity

Alzheimer's disease research and treatmentsMemory and Neural Mechanisms

Cited by 198

Increased Vulnerability of Hippocampal Neurons from Presenilin‐1 Mutant Knock‐In Mice to Amyloid β‐Peptide Tox: Central Roles of Superoxide Production and Caspase Activation

Guo, Q., Sebastian, L., Sopher, B. L., Miller, M. W., Ware, C. B., Martin, G. M., & Mattson, M. P. (1999) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 197

Secreted β-Amyloid Precursor Protein Counteracts the Proapoptotic Action of Mutant Presenilin-1 by Activation of NF-κB and Stabilization of Calcium Homeostasis

Guo, Q., Robinson, N., & Mattson, M. P. (1998) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsNF-κB Signaling Pathways

Cited by 196

Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation

Obregon, D., Hou, H., Deng, J., Giunta, B., Tian, J., Darlington, D., Shahaduzzaman, M., Zhu, Y., Mori, T., Mattson, M. P., et al. (2012) · Nature Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 192

Tomatidine Enhances Lifespan and Healthspan in C. elegans through Mitophagy Induction Via the SKN-1/Nrf2 Pathway

Fang, E. F., Waltz, T. B., Kassahun, H., Lu, Q., Kerr, J. S., Morevati, M., Fivenson, E. M., Wollman, B. N., Marosi, K., Wilson, M. A., et al. (2017) · Scientific Reports

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 187

Brain‐derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health

Rothman, S. M., Griffioen, K. J., Wan, R., & Mattson, M. P. (2012) · Annals of the New York Academy of Sciences

Regulation of Appetite and ObesityNerve injury and regeneration

Cited by 185

Dietary Restriction Stimulates BDNF Production in the Brain and Thereby Protects Neurons Against Excitotoxic Injury

Duan, W., Lee, J., Guo, Z., & Mattson, M. P. (2001) · Journal of Molecular Neuroscience

Nerve injury and regenerationGenetics, Aging, and Longevity in Model Organisms

Cited by 183

4-Hydroxynonenal, a product of lipid peroxidation, inhibits dephosphorylation of the microtubule-associated protein tau

Mattson, M. P., Fu, W., Waeg, G., & Uchida, K. (1997) · NeuroReport

Alzheimer's disease research and treatmentsAldose Reductase and Taurine

Cited by 176

SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice

Liu, Y., Cheng, A., Li, Y.-J., Yang, Y., Kishimoto, Y., Zhang, S., Wang, Y., Wan, R., Raefsky, S. M., Lu, D., et al. (2019) · Nature Communications

Dietary Effects on HealthSirtuins and Resveratrol in Medicine

Cited by 176

The Catalytic Subunit of Telomerase Protects Neurons Against Amyloid β‐Peptide‐Induced Apoptosis

Zhu, H., Fu, W., & Mattson, M. P. (2000) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsTelomeres, Telomerase, and Senescence

Cited by 175

Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Aβ and pTau in a mouse model of Alzheimer's disease

Rothman, S. M., Herdener, N., Frankola, K. A., Mughal, M. R., & Mattson, M. P. (2013) · Brain Research

Alzheimer's disease research and treatmentsSleep and Wakefulness Research

Cited by 172

Basic FGF attenuates amyloid β-peptide-induced oxidative stress, mitochondrial dysfunction, and impairment of Na+/K+-ATPase activity in hippocampal neurons

Mark, R. J., Keller, J. N., Kruman, I., & Mattson, M. P. (1997) · Brain Research

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 167

Calcium and Neuronal Injury in Alzheimer's Disease: Contributions of β‐Amyloid Precursor Protein Mismetabolism, Free Radicals, and Metabolic Compromisea

MATTSON, M. P. (1994) · Annals of the New York Academy of Sciences

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 166

BDNF and exercise enhance neuronal DNA repair by stimulating CREB-mediated production of apurinic/apyrimidinic endonuclease 1

Yang, J.-L., Lin, Y.-T., Chuang, P.-C., Bohr, V. A., & Mattson, M. P. (2014) · NeuroMolecular Medicine

Nerve injury and regenerationDNA Repair Mechanisms

Cited by 159

Molecular mechanisms of brain aging and neurodegenerative disorders: Lessons from dietary restriction

Prolla, T. A., & Mattson, M. P. (2001) · Trends in Neurosciences

Genetics, Aging, and Longevity in Model OrganismsAntioxidants, Aging, Portulaca oleracea

Cited by 159

Telomere shortening in neurological disorders: an abundance of unanswered questions

Eitan, E., Hutchison, E. R., & Mattson, M. P. (2014) · Trends in Neurosciences

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 158