Zhang, Dong-Er

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice

Zhang, D.-E., Zhang, P., Wang, N.-D., Hetherington, C. J., Darlington, G. J., & Tenen, D. G. (1997) · Proceedings of the National Academy of Sciences

Acute Myeloid Leukemia ResearchBlood disorders and treatments

Cited by 910

Transcription Factors, Normal Myeloid Development, and Leukemia

Tenen, D. G., Hromas, R., Licht, J. D., & Zhang, D.-E. (1997) · Blood

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 735

AML1–ETO downregulates the granulocytic differentiation factor C/EBPα in t(8;21) myeloid leukemia

Pabst, T., Mueller, B. U., Harakawa, N., Schoch, C., Haferlach, T., Behre, G., Hiddemann, W., Zhang, D.-E., & Tenen, D. G. (2001) · Nature Medicine

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 463

The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor

Zhang, D.-E., Hetherington, C. J., Chen, H.-M., & Tenen, D. G. (1994) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsImmune cells in cancer

Cited by 411

CCAAT Enhancer-Binding Protein (C/EBP) and AML1 (CBFα2) Synergistically Activate the Macrophage Colony-Stimulating Factor Receptor Promoter

Zhang, D.-E., Hetherington, C. J., Meyers, S., Rhoades, K. L., Larson, C. J., Chen, H.-M., Hiebert, S. W., & Tenen, D. G. (1996) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 396

Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene

Yergeau, D. A., Hetherington, C. J., Wang, Q., Zhang, P., Sharpe, A. H., Binder, M., Marín-Padilla, M., Tenen, D. G., Speck, N. A., & Zhang, D.-E. (1997) · Nature Genetics

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 346

The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter

Pahl, H. L., Scheibe, R. J., Zhang, D. E., Chen, H. M., Galson, D. L., Maki, R. A., & Tenen, D. G. (1993) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsCell Adhesion Molecules Research

Cited by 301

PU.1 (Spi-1) and C/EBPα Regulate Expression of the Granulocyte-Macrophage Colony-Stimulating Factor Receptor α Gene

Hohaus, S., Petrovick, M. S., Voso, M. T., Sun, Z., Zhang, D.-E., & Tenen, D. G. (1995) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsCytokine Signaling Pathways and Interactions

Cited by 284

A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis.

Yan, M., Kanbe, E., Peterson, L. F., Boyapati, A., Miao, Y., Wang, Y., Chen, I.-M., Chen, Z., Rowley, J. D., Willman, C. L., et al. (2006) · Nature Medicine

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 279

Multiple Functional Domains of AML1: PU.1 and C/EBPα Synergize with Different Regions of AML1

Petrovick, M. S., Hiebert, S. W., Friedman, A. D., Hetherington, C. J., Tenen, D. G., & Zhang, D.-E. (1998) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 218

Identification of a Region Which Directs the Monocytic Activity of the Colony-Stimulating Factor 1 (Macrophage Colony-Stimulating Factor) Receptor Promoter and Binds PEBP2/CBF (AML1)

Zhang, D.-E., Fujioka, K.-I., Hetherington, C. J., Shapiro, L. H., Chen, H.-M., Look, A. T., & Tenen, D. G. (1994) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsCytokine Signaling Pathways and Interactions

Cited by 199

The Sp1 transcription factor binds the CD11b promoter specifically in myeloid cells in vivo and is essential for myeloid-specific promoter activity.

Chen, H. M., Pahl, H. L., Scheibe, R. J., Zhang, D. E., & Tenen, D. G. (1993) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsCell Adhesion Molecules Research

Cited by 199

c-Jun Is a JNK-independent Coactivator of the PU.1 Transcription Factor

Behre, G., Whitmarsh, A. J., Coghlan, M. P., Hoang, T., Carpenter, C. L., Zhang, D.-E., Davis, R. J., & Tenen, D. G. (1999) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsCytokine Signaling Pathways and Interactions

Cited by 180

Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis.

Rhoades, K. L., Hetherington, C. J., Rowley, J. D., Hiebert, S. W., Nucifora, G., Tenen, D. G., & Zhang, D. E. (1996) · Proceedings of the National Academy of Sciences

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 129

Negative regulation of type I IFN signaling

Arimoto, K.-I., Miyauchi, S., Stoner, S. A., Fan, J.-B., & Zhang, D.-E. (2018) · Journal of Leukocyte Biology

interferon and immune responsesImmune Response and Inflammation

Cited by 117

Functional characterization of ETV6 and ETV6/CBFA 2 in the regulation of the MCSFR proximal promoter

Fears, S., Gavin, M., Zhang, D.-E., Hetherington, C., Ben-David, Y., Rowley, J. D., & Nucifora, G. (1997) · Proceedings of the National Academy of Sciences

Acute Lymphoblastic Leukemia researchGenomics and Chromatin Dynamics

Cited by 78

MicroRNA programs in normal and aberrant stem and progenitor cells

Arnold, C. P., Tan, R., Zhou, B., Yue, S.-B., Schaffert, S., Biggs, J. R., Doyonnas, R., Lo, M.-C., Perry, J. M., Renault, V. M., et al. (2011) · Genome Research

MicroRNA in disease regulationHematopoietic Stem Cell Transplantation

Cited by 65

Octamer Binding Factors and Their Coactivator Can Activate the Murine PU.1 (spi-1) Promoter

Chen, H.-M., Zhang, P., Radomska, H. S., Hetherington, C. J., Zhang, D.-E., & Tenen, D. G. (1996) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 59