Czech, Michael P.

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes.

Guilherme, A., Virbasius, J. V., Puri, V., & Czech, M. P. (2008) · Nature Reviews Molecular Cell Biology

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 2,292

Insulin action and resistance in obesity and type 2 diabetes

Czech, M. P. (2017) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 1,258

Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone.

Wilson-Fritch, L., Nicoloro, S., Chouinard, M., Lazar, M. A., Chui, P. C., Leszyk, J., Straubhaar, J., Czech, M. P., & Corvera, S. (2004) · Journal of Clinical Investigation

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 616

What causes the insulin resistance underlying obesity?

Hardy, O. T., Czech, M. P., & Corvera, S. (2012) · Current Opinion in Endocrinology, Diabetes & Obesity

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 563

Mitochondrial biogenesis and remodeling during adipogenesis and in response to the insulin sensitizer rosiglitazone.

Wilson-Fritch, L., Burkart, A., Bell, G., Mendelson, K., Leszyk, J., Nicoloro, S., Czech, M., & Corvera, S. (2003) · Molecular and Cellular Biology

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 459

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

Jourdan, T., Godlewski, G., Cinar, R., Bertola, A., Szanda, G., Liu, J., Tam, J., Han, T., Mukhopadhyay, B., Skarulis, M. C., et al. (2013) · Nature Medicine

Pancreatic function and diabetesInflammasome and immune disorders

Cited by 388

Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing

Jiang, Z. Y., Zhou, Q. L., Coleman, K. A., Chouinard, M., Boese, Q., & Czech, M. P. (2003) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 378

Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction

Sun, K., Park, J., Gupta, O. T., Holland, W. L., Auerbach, P., Zhang, N., Goncalves Marangoni, R., Nicoloro, S. M., Czech, M. P., Varga, J., et al. (2014) · Nature Communications

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 364

Depot-Specific Differences and Insufficient Subcutaneous Adipose Tissue Angiogenesis in Human Obesity

Gealekman, O., Guseva, N., Hartigan, C., Apotheker, S., Gorgoglione, M., Gurav, K., Tran, K.-V., Straubhaar, J., Nicoloro, S., Czech, M. P., et al. (2011) · Circulation

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 346

Epicardial and perivascular adipose tissues and their influence on cardiovascular disease: Basic mechanisms and clinical associations

Fitzgibbons, T. P., & Czech, M. P. (2014) · Journal of the American Heart Association

Cardiovascular Disease and AdiposityAdipokines, Inflammation, and Metabolic Diseases

Cited by 331

An essential role of the JIP1 scaffold protein for JNK activation in adipose tissue

Jaeschke, A., Czech, M. P., & Davis, R. J. (2004) · Genes & Development

Adipokines, Inflammation, and Metabolic DiseasesProtein Tyrosine Phosphatases

Cited by 121

Paradoxical effect of mitochondrial respiratory chain impairment on insulin signaling and glucose transport in adipose cells.

Shi, X., Burkart, A., Nicoloro, S. M., Czech, M. P., Straubhaar, J., & Corvera, S. (2008) · Journal of Biological Chemistry

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 70

An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis

Yenilmez, B., Wetoska, N., Kelly, M., Echeverria, D., Min, K., Lifshitz, L., Alterman, J. F., Hassler, M. R., Hildebrand, S., DiMarzio, C., et al. (2022) · Molecular Therapy

Liver Disease Diagnosis and TreatmentRNA Interference and Gene Delivery

Cited by 46