Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

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Cannabinoids as Key Regulators of Inflammasome Signaling: A Current Perspective

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Silencing of KCNQ1OT1 Decreases Oxidative Stress and Pyroptosis of Renal Tubular Epithelial Cells

Zhu, B. L., Cheng, X., Yilan, J., Cheng, M. Y., Chen, L., Bao, J., & Tang, X. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s225791 · Cited by 81 · see citing works

Inhibiting the NLRP3 inflammasome with MCC950 ameliorates retinal neovascularization and leakage by reversing the IL-1β/IL-18 activation pattern in an oxygen-induced ischemic retinopathy mouse model

Sui, A., Chen, X., Shen, J., Demetriades, A. M., Yao, Y., Yao, Y., Zhu, Y., Shen, X. P., & Xie, B. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-03076-7 · Cited by 80 · see citing works

Cannabidiol protects livers against nonalcoholic steatohepatitis induced by high‐fat high cholesterol diet via regulating NF‐κB and NLRP3 inflammasome pathway

Huang, Y., Wan, T., Pang, N., Zhou, Y., Jiang, X., Li, B., Gu, Y., Huang, Y., Ye, X., Lian, H., et al. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28728 · Cited by 79 · see citing works

Macrophages mediate β-cell loss in T2DM

Kugelberg, E. (2013) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2013.177 · Cited by 5 · see citing works

Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type 2 Diabetes

Jourdan, T., Szanda, G., Çınar, R., Godlewski, G., Holovac, D. J., Park, J. K., Nicoloro, S. M. C., Shen, Y., Liu, J., Rosenberg, A. Z., et al. (2017) · Diabetes · doi:10.2337/db16-1199 · Cited by 44 · see citing works

Evidence against a role for NLRP3-driven islet inflammation in db/db mice

Kammoun, H. L., Allen, T. L., Henstridge, D. C., Barre, S., Coll, R. C., Lancaster, G. I., Cron, L., Reibe, S., Chan, J. Y., Bensellam, M., et al. (2018) · Molecular Metabolism · doi:10.1016/j.molmet.2018.02.001 · Cited by 41 · see citing works

Toll‐like receptors and NLRP3 as central regulators of pancreatic islet inflammation in type 2 diabetes

Westwell-Roper, C. Y., Nąckiewicz, D., Dan, M., & Ehses, J. A. (2014) · Immunology and Cell Biology · doi:10.1038/icb.2014.4 · Cited by 73 · see citing works

Deactivation of the NLRP3 inflammasome in infiltrating macrophages by duodenal-jejunal bypass surgery mediates improvement of beta cell function in type 2 diabetes.

Wu, D., Yan, Z.-B., Cheng, Y.-G., Zhong, M.-W., Liu, S.-Z., Zhang, G.-Y., & Hu, S.-Y. (2018) · Metabolism: Clinical and Experimental · doi:10.1016/j.metabol.2017.10.015 · Cited by 35 · see citing works